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wt decrease » we decrease (Expand Search), nn decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decreased (Expand Search), _ decreases (Expand Search)
m decrease » _ decreased (Expand Search), _ decreases (Expand Search), a decreased (Expand Search)
12 m » 12 mm (Expand Search), 12 mg (Expand Search), 12 _ (Expand Search)
wt decrease » we decrease (Expand Search), nn decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decreased (Expand Search), _ decreases (Expand Search)
m decrease » _ decreased (Expand Search), _ decreases (Expand Search), a decreased (Expand Search)
12 m » 12 mm (Expand Search), 12 mg (Expand Search), 12 _ (Expand Search)
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Acer3 knockout decreases alkaline ceramidase activity on ULCC in the brain.
Published 2015“…Reduction of alkaline ceramidase activity on NBD-C<sub>12</sub>-PHC in Acer3<sup>-/-</sup> mice. Note that Acer3<sup>-/-</sup> mice at either 6W or 8M of age show significant declines in ceramidase activity in both the cerebellar and cerebral brains compared to their WT littermates. …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…[NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Deletion of TXNIP decreases thioredoxin levels under hyperoxic conditions.
Published 2014“…Exposure of TKO pups to hyperoxia significantly decreased the anti-apoptotic thioredoxin on both mRNA as well as protein level compared to WT. …”
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