Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells حسب Posadino, Anna Maria

"…Failure of PE to induce PC3 damage in cells overexpressing Akt further confirms its implication in the PE-elicited cell death. …"
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Credit bureaus and financial constraints do corruption matter? حسب Ben Ali, Mohamed Sami

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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines حسب Prabhu K.S.

"…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. …"
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway حسب Anwar, M. Akhtar

"…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. …"
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling حسب Chung, Jihyun

"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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Mechanical characteristics of ultra-high performance steel FRC made with recycled concrete aggregates حسب Alnahhal, W.

"…However, the flowability was decreased by 12% to 15% with steel fibers. The results also revealed that at a steel fiber volume fraction of 0%, RCA had little influence on the compressive strength, while they noticeably influenced the flexural tensile strength. …"
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Simulation and experimental study of underwater dissimilar friction-stir welding between aluminium and steel حسب Eyvazian, Arameh

"…The average grainsize in the aluminum and steel sides of SZ is refined down to ?4 and 12-m, respectively. …"
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

"…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …"
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Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride حسب Radwan A.B.

"…In conclusion, this new inhibitor shows high corrosion inhibition efficiencies under different aggressive conditions and can be used in concrete to reduce the corrosion rate of reinforcing steel without decreasing the mechanical properties of the concrete. - 2019, The Author(s).…"
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Mechanical Properties of Concrete Made with Electric Wires, Steel Fibers, Basalt Fibers and Polypropylene Fibers حسب Murad, Yasmin Zuhair

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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…An extensive two-step molecular dynamics (simple and complex) simulation (MDS) using GROMACS (GROningen MAchine for Chemical Simulations) was then initiated to analyze and understand the structural impact of the E17K mutation on the function of AKT1. The simple MDS analysis revealed that the E17K mutation decreases the compactness and intramolecular hydrogen bonds of the protein. …"
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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway حسب Hadrich, F.

"…Moreover, the cotreatment of EE 1/1000 or oleuropein with insulin increased considerably the expression of p-IRS, p85-pI3K, and p-AKT. In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. …"
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Corrosion inhibition of Mild Steel at Elevated temperature in highly Acidic Brines using a green corrosion inhibitor حسب Elhaddad, Muhsen A.M.

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Electrochemical Investigation of C-Steel Corrosion Inhibition, In Silico, and Sulfate-Reducing Bacteria Investigations Using Pyrazole Derivatives حسب Shaban, Mahmoud M.

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Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution حسب Shahzad, Khuram

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Local supersaturation and the growth of protective scales during CO2 corrosion of steel: Effect of pH and solution flow حسب Sk, Mobbassar Hassan

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An efficient green ionic liquid for the corrosion inhibition of reinforcement steel in neutral and alkaline highly saline simulated concrete pore solutions حسب Sliem, Mostafa H.

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An Eco-Friendly Quaternary Ammonium Salt as a Corrosion Inhibitor for Carbon Steel in 5 M HCl Solution: Theoretical and Experimental Investigation حسب Jalab, Rem

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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events حسب Raj, K. Diraviya

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