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PBA decreases ER stress induced apoptosis.
Published 2010“…All three ER stress inducing agents elicited a two-three fold increase in pycnotic nuclei. The fraction of cells with pycnotic nuclei decreased with PBA treatment—in the thapsigargin treated cells, the number of pycnotic nuclei was identical to the untreated cells by 1 mM PBA, and by 5 mM PBA the fraction of cells with pycnotic nuclei reached basal levels in all three treatment groups (B).…”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”
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SGK1 expression is significantly decreased in the prefrontal cortex of PTSD patients.
Published 2015“…Data are expressed as a mean fold change ± standard error of the mean (SEM) (<i>n</i> = 6), compared to healthy controls (<i>n</i> = 6). …”
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Model performance according to number of variables by 5-fold cross-validation.
Published 2023Subjects: -
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WNT3 decreases GCP proliferation by inhibiting SHH dependent gene transcription.
Published 2013“…<p>(<i>A</i>) WNT3 decreased proliferation of GCPs by 40.3± 5.0% of the control (Con) (n=3) as measured by [<sup>3</sup>H]-Thymidine incorporation assay. …”
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The proportional decrease in chamber area with depth of nests is similar no matter what the colony size
Published 2011“…</p> Every 10-fold increase in depth is associated with a 75% decrease in summed chamber area in the decile (note log-log scale). …”
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