Search alternatives:
wt decrease » we decrease (Expand Search), nn decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decreased (Expand Search), _ decreases (Expand Search)
_ decrease » _ decreased (Expand Search)
g decrease » gy decreased (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 g » 5 mg (Expand Search)
wt decrease » we decrease (Expand Search), nn decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decreased (Expand Search), _ decreases (Expand Search)
_ decrease » _ decreased (Expand Search)
g decrease » gy decreased (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 g » 5 mg (Expand Search)
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The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties.
Published 2020“…<i>n</i> = 73 oocytes for WT (5.70 ± 0.61 μA) and 59 oocytes for C456Y (0.039 ± 0.004 μA), ***<i>P</i> < 0.001, Mann-Whitney. …”
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Decreased hyper-resection in a NuA4 acetylation defective mutant in G1 and defect in DNA break repair by SSA.
Published 2021“…<p>(A-B) ChIP-qPCR of Rad52 around the HO-induced DSB in G1 blocked cells. <i>rad9</i>Δy<i>ku80</i>Δ, y<i>ku80</i>Δ (A) and <i>nej1</i>Δ (B) show higher recruitment of Rad52 compared to wild type conditions. …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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