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Isotonic Glycerol and Sodium Hyaluronate Containing Artificial Tear Decreases Conjunctivochalasis after One and Three Months: A Self-Controlled, Unmasked Study
Published 2015“…Conjunctivochalasis decreased from a mean LIPCOF degree of 2.9±0.4 on both eyes to 1.4±0.6 on the right (median decrease of -2 points, 95% CI from -2.0 to -1.0), and to 1.4±0.7 on the left eye (median decrease of -1 points, 95% CI from -2.0 to -1.0) (p<0.001 for both sides). …”
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PBA decreases ER stress induced apoptosis.
Published 2010“…All three ER stress inducing agents elicited a two-three fold increase in pycnotic nuclei. The fraction of cells with pycnotic nuclei decreased with PBA treatment—in the thapsigargin treated cells, the number of pycnotic nuclei was identical to the untreated cells by 1 mM PBA, and by 5 mM PBA the fraction of cells with pycnotic nuclei reached basal levels in all three treatment groups (B).…”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…[NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].</p>…”
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The combination of LPS and PFC caused faster clot initiation and decreased clot strength.
Published 2022“…Comparing groups, there is a significant decline in TEG MA in LPS-PFC3 group compared to LPS-SAL group at T72 and T96 time points (p<0.05). By RM ANOVA, the time effects were obscured by interaction with group: SAL-SAL, p = NS; LPS-SAL, MA increases with time; T0 v T72 and T96, p≤0.05; SAL-PFC: MA drops @ T96, p≤0.05; LPS-PFC: T0 v all others, p≤0.05 with a recovery at T96, (p≤0.05 compared to T72); SAL-PFC: no significant change, p = NS. …”
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Decreased hyper-resection in a NuA4 acetylation defective mutant in G1 and defect in DNA break repair by SSA.
Published 2021“…(F) The <i>esa1-ts</i> mutation leads to a decrease of DSB repair by resection-based single-strand annealing. …”
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