Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects by Alsaad A.M.

“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes by Younes, Noura B.

“…The exposure of adipocytes to 1% hypoxia significantly alters the transcript of hypoxia genes, and other genes involved in glucose (GLUT1, GLUT4) and lipid (PPAR-γ) metabolism, and is also linked to anaerobic metabolism with apoptosis and increased oxidative stress. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …”
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Sorption of benzene and naphthalene on (semi)-arid coastal soil as a function of salinity and temperature by NgueleuS.K.

“…To quantify the sorption rates of PHCs in (semi)-arid coastal soil environments, we conducted a series of controlled-laboratory batch experiments under variable temperature and salinity conditions. …”
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Al-Amleh, Esraa K.

“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. by Gomes da Silva, Isaura Isabelle Fonseca

“…No significant differences were observed for MYD88 gene expression (FC = 1.20; p = 0.294) between patients and controls analyzed. …”
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Credit bureaus and financial constraints do corruption matter? by Ben Ali, Mohamed Sami

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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... by Anwar-Mohamed, Anwar

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Semi-continuous anaerobic digestion of the organic fraction of municipal solid waste: digester performance and microbial population dynamics by Najoua, Mlaik

“…Anaerobic digestion is an attractive approach for the management of organic fraction of municipal solid waste (OFMSW) and for the recovery of energy from this waste. A semi-continuous digestion of OFMSW was conducted on stirred reactor under mesophilic condition. …”
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MHD effects on nanofluid with energy and hydrothermal behavior between two collateral plates application of new semi analytical technique by Sheikholeslami, Mohsen

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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model by Al-Awar A.

“…Hearts were then isolated and subjected to two different I/R injury protocols: 10 min perfusion, 45 min regional ischemia, and 120 min reperfusion for infarct size (IS) measurement, or: 10 min perfusion, 45 min regional ischemia and 10 min reperfusion for biochemical analysis: nitric oxide synthases (NOSs) and DPP-4 activity, glucagon-like peptide-1 (GLP-1), Calcium, transient receptor potential vanilloid (TRPV)-1 and calcitonin gene-related peptide (CGRP) levels, transient receptor potential canonical (TRPC)-1 and e-NOS protein expression. …”
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PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT by AHMED, AMIRA

“…Aim: This study explores the impact of SNF on OS in diet induced obese (DIO) mice via profiling of OS genes and pathways in skeletal muscles related to the anti-obesity effect. …”
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Organic materials amendments can improve NPK availability and maize growth by reducing heavy metals stress in calcareous soil by Saleem, A.

“…The deficiency of nitrogen (N) and phosphorus (P) in calcareous soils of semi-arid climates is well recognized, and various green-based strategies have been employed to enhance their availability. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR by ABDULKADER, HADIL

“…Women showed a strong association with obesity compared to men (OR: 1.51, 95% CL: 1.32-1.73), while smokers and ex-smokers had a decreased odds of having obesity by 21% and 12% respectively in comparison to nonsmokers. …”
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway by Kuttikrishnan, Shilpa

“…Moreover, NSP-B suppressed FOXM1-regulated genes, such as Aurora Kinases A and B, CDKs 4 and 6, and PLK1. …”
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Identification of key genes regulating macronutrient accumulation and final yield in wheat under potassium deficiency by Thabet, Samar G.

“…Interestingly, the TraesCS1B02G359800 gene was located on chromosome 3B and annotated as protein kinases that harbor the variation of NGS, P, Mg_K2, and Mg_K1. …”
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The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets by Cenciarelli, Carlo

“…In the current study, we assessed the effects of Hes1-targeted shRNA, a Notch1 gene target, specifically on GBM CSC refractory to GSI-X. …”
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS by AL-SADEQ, DUAA WALID

“…This reduced activity is consistent with both in vitro and in silico evidence, which indicates that the studied CBS mutations, except p.K72I, significantly decrease the overall protein's stability, which may represent the underlying cause of their pathogenicity. …”
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