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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
Published 2015“…The exposure of adipocytes to 1% hypoxia significantly alters the transcript of hypoxia genes, and other genes involved in glucose (GLUT1, GLUT4) and lipid (PPAR-γ) metabolism, and is also linked to anaerobic metabolism with apoptosis and increased oxidative stress. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …”
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
Published 2022“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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Credit bureaus and financial constraints do corruption matter?
Published 2022“…Our findings suggest that curbing corruption creates more efficient credit bureaus that, in turn, decrease financial constraints for firms. The subsample estimations confirm these findings and show that the higher and longer-term corruption in MENA countries than in Eastern European countries make credit bureaus' less effective, imposing more financial constraints. …”
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.
Published 2021“…No significant differences were observed for MYD88 gene expression (FC = 1.20; p = 0.294) between patients and controls analyzed. …”
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model
Published 2018“…Hearts were then isolated and subjected to two different I/R injury protocols: 10 min perfusion, 45 min regional ischemia, and 120 min reperfusion for infarct size (IS) measurement, or: 10 min perfusion, 45 min regional ischemia and 10 min reperfusion for biochemical analysis: nitric oxide synthases (NOSs) and DPP-4 activity, glucagon-like peptide-1 (GLP-1), Calcium, transient receptor potential vanilloid (TRPV)-1 and calcitonin gene-related peptide (CGRP) levels, transient receptor potential canonical (TRPC)-1 and e-NOS protein expression. …”
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Swimming exercise improves short- and long-term memories: Time-course changes
Published 2021“…Young adult Wistar rats were tested for both short-term and long-term memories using the radial arm water maize (RAWM) paradigm following 0, 1, 7, 14, and 28 days of swimming exercise training (60 min per day, 5 days/week)s. …”
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Long-term performance analysis and power prediction of PV technology in the State of Qatar
Published 2017“…Solar photovoltaic (PV) energy in GCC?- the term seems convincing to many solar PV industries due to high solar exposure in GCC region. …”
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Long – Term Soaking Effect On Strength And Deformation Characteristics Of A Gypsiferous Subgrade Soil
Published 2003“…The behaviour during long-term soaking of the California Bearing Ratio (CBR), the resilient modulus and the deformation of compacted Iraqi gypsiferous soil containing about 34% gypsum was studied. …”
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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center
Published 2018“…Conclusions: Our program and its findings in terms of much improved blood delivery TAT after implementing this quality improvement approach represent an appropriate and effective solution to the challenge of making blood available fast enough to meet true hemorrhagic emergencies.…”
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Rheological evaluation of shortand long-term performance for warm mix asphalt (WMA) binders
Published 2016“…Different ageing processes were performed in this study; half and full short-term ageing using the Rolling Thin Film Oven (RTFO) procedure, and long-term ageing using the Pressurized Ageing Vessel (PAV) procedure. …”
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PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT
Published 2021“…Aim: This study explores the impact of SNF on OS in diet induced obese (DIO) mice via profiling of OS genes and pathways in skeletal muscles related to the anti-obesity effect. …”
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Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey.
Published 2020“…We aimed to examine the association between long-term egg consumption and its trajectory with diabetes in Chinese adults. …”
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Short-term effects of warming treatment and precipitation manipulation on the ecophysiological responses of pinus densiflora seedlings
Published 2016“…The aim of this study was to investigate the short-term effects of warming treatment and precipitation manipulation on the growth, photosynthetic rate, and chlorophyll content of Pinus densiflora seedlings based on a climate change scenario in Korea. …”
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