Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Al-Amleh, Esraa K.

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
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Evidence of two mechanisms involved in Bacillus thuringiensis israelensis decreased toxicity against mosquito larvae: Genome dynamic and toxins stability حسب Elleuch, Jihen

"…This bacterium is characterized by a dynamic genome able to win or lose genetic materials which leads to a decrease in its effectiveness. …"
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

"…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …"
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Credit bureaus and financial constraints do corruption matter? حسب Ben Ali, Mohamed Sami

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Bordetella pertussis risA, but not risS, is required for maximal expression of Bvg-repressed genes حسب Stenson, Trevor H.

"…However, decreased invasion could not be attributed to the decreased expression of Bvg-repressed products, suggesting that mutation of risA may affect the expression of a variety of genes. …"
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PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT حسب AHMED, AMIRA

"…Conclusion: This study demonstrated that SFN had lowered body weight in WT-DIO mice by decreasing OS damage in skeletal muscles through the NrF2 pathway and can be a potential anti-obesity drug.…"
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Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia حسب Ibrahim, Ali Zaki

"…Propionic Acidemia (PA) is an inborn error of metabolism caused by variants in the or genes, leading to mitochondrial accumulation of propionyl-CoA and its by-products. …"
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Growth performance, intestinal histomorphology, gut microflora and ghrelin gene expression analysis of broiler by supplementing natural growth promoters: A nutrigenomics approach حسب Gilani, S.M.H.

"…Addition of phytobiotics significantly improved (p < 0.05) villus height and ratio of villus height/crypt depth in ileum, jejunum, and duodenum and down-regulated ghrelin gene expression levels. Total coliform and Escherichia coli in cecal and ileal digesta were decreased significantly (p < 0.05) in organic acids group. …"
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…The exposure of adipocytes to 1% hypoxia significantly alters the transcript of hypoxia genes, and other genes involved in glucose (GLUT1, GLUT4) and lipid (PPAR-γ) metabolism, and is also linked to anaerobic metabolism with apoptosis and increased oxidative stress. …"
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INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR حسب ABDULKADER, HADIL

"…Circadian rhythms are maintained by a transcriptional auto-regulatory feedback loop including core clock genes. …"
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Identification of key genes regulating macronutrient accumulation and final yield in wheat under potassium deficiency حسب Thabet, Samar G.

"…The wheat grains were analyzed for four macronutrients, mainly magnesium (Mg), calcium (Ca), potassium (K), and phosphorus (P), as well as yield attributes, under both treatments. A statistically significant decrease was observed for all assessed minerals and yield traits in wheat accessions under low potassium. …"
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS حسب AL-SADEQ, DUAA WALID

"…Homocystinuria, a rare disorder stemming from mutations in the CBS gene, results in cystathionine β-synthase (CBS) deficiency. …"
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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria حسب Al-Sadeq, Duaa W.

"…Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). …"
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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

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Green Revolution dwarfing Rht genes negatively affected wheat floral traits related to cross-pollination efficiency حسب Schierenbeck, Matías

"…Hybrid breeding is a promising strategy to quickly improve wheat yield and stability. …"
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Transcriptome assembly, profiling and differential gene expression analysis of the halophyte Suaeda fruticosa provides insights into salt tolerance حسب Diray-Arce, Joann

"…However, little is known about the genes involved in salt tolerance. We have characterized the transcriptome of Suaeda fruticosa, a halophyte that has the ability to sequester salts in its leaves. …"
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Cardiac Myosin Binding Protein-C in Sprague Dawley (SD) Rats exposed to Sub-Chronic oral dose of Cadmium Chloride حسب Al-Borshaid, Enjoud Khalifa

"…The data demonstrated that cadmium decreased cMyBP-C at the protein level and downregulated its expression at the gene level. …"
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

"…Sitg oral treatment of different doses (25, 50, 100, and 150 mg/kg/day), or saline as a Control. Hearts were then isolated and subjected to two different I/R injury protocols: 10 min perfusion, 45 min regional ischemia, and 120 min reperfusion for infarct size (IS) measurement, or: 10 min perfusion, 45 min regional ischemia and 10 min reperfusion for biochemical analysis: nitric oxide synthases (NOSs) and DPP-4 activity, glucagon-like peptide-1 (GLP-1), Calcium, transient receptor potential vanilloid (TRPV)-1 and calcitonin gene-related peptide (CGRP) levels, transient receptor potential canonical (TRPC)-1 and e-NOS protein expression. …"
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…We suggested that IRAK3 gene expression in CD14 + monocytes appears to be relevant to the RA etiology and clinical activity, whereas, in this study, MYD88 does not play a role in RA onset and development.…"
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