يعرض 1 - 20 نتائج من 274 نتيجة بحث عن '(( 59 ((a decrease) OR (_ decrease)) ) OR ((( a step decrease ) OR ( _ akt decrease ))))*', وقت الاستعلام: 0.16s تنقيح النتائج
  1. 1
  2. 2
  3. 3
  4. 4

    Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines حسب Prabhu K.S.

    منشور في 2018
    "…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. …"
    احصل على النص الكامل
    احصل على النص الكامل
  5. 5
  6. 6

    Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway حسب Anwar, M. Akhtar

    منشور في 2017
    "…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. …"
    احصل على النص الكامل
    احصل على النص الكامل
  7. 7

    Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling حسب Chung, Jihyun

    منشور في 2019
    "…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
    احصل على النص الكامل
    احصل على النص الكامل
  8. 8

    Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

    منشور في 2018
    "…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …"
    احصل على النص الكامل
    احصل على النص الكامل
  9. 9

    Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway حسب Hadrich, F.

    منشور في 2023
    "…Moreover, the cotreatment of EE 1/1000 or oleuropein with insulin increased considerably the expression of p-IRS, p85-pI3K, and p-AKT. In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. …"
    احصل على النص الكامل
    احصل على النص الكامل
  10. 10

    A Reverse MultipleChoice Based mLearning System حسب Karkar, AbdelGhani

    منشور في 2018
    "…Using a knowledge base, a set of answer choices will be created for a multiple-choice question. …"
    احصل على النص الكامل
    احصل على النص الكامل
  11. 11

    Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions حسب Salih, Isam M.

    منشور في 2013
    "…The mechanism of the title reaction is consistent with an inner sphere mechanism in which a pre-equilibrium step precedes the electron transfer step. …"
    احصل على النص الكامل
    احصل على النص الكامل
  12. 12

    Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach حسب P., Sneha

    منشور في 2017
    "…Missense mutations of the HNF1A were retrieved from public databases and subjected to a three-step computational mutational analysis to identify the underlying mechanism. …"
    احصل على النص الكامل
    احصل على النص الكامل
  13. 13
  14. 14
  15. 15

    A new insight into the separation of oil from oil/water emulsion by Fe3O4?SiO2 nanoparticles حسب Elmobarak W.F.

    منشور في 2021
    "…Moreover, the results exhibited that the reservoir conditions are a crucial function for increasing the oil recovery rates, improving the emulsion stability, and acts as a substantial step for the oil recovery method that applies this particular technique.…"
    احصل على النص الكامل
    احصل على النص الكامل
  16. 16
  17. 17
  18. 18

    A process for CO2 capture and brine salinity reduction through reaction with potassium hydroxide: A multi-stage evaluation حسب Mourad, Aya A-H.

    منشور في 2022
    "…Solvay and modified Solvay processes are facing a major challenge in reducing brine salinity to a level suitable for agriculture and industry. …"
    احصل على النص الكامل
    احصل على النص الكامل
  19. 19

    Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Al-Sulaiti, Fatima Khalifa

    منشور في 2024
    "…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …"
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
  20. 20

    On the application of arabian gulf water in irrigation: A future possibility حسب Abu Sharar, Taleb [طالب ابو شرار]

    منشور في 1987
    "…Barley can tolerate 12 dS m water salinity without any apparent yeild decrement. Yield would decrease by 5% per each additional increment in water salinity beyond 12 dS m Thus, if Gulf water salinity was treated according to the model of plant response to time weighted salinity, then barley could alternatively be irrigated with fresh/Gulf water in a way that would save a minimum of 16% of the applied water. …"
    احصل على النص الكامل