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Maximum Likelihood Estimation in the Inverse Weibull Distribution with Type II Censored Data
Published 2022“…We consider maximum likelihood estimation for the parameters and certain functions of the parameters in the Inverse Weibull (IW) distribution based on type II censored data. The functions under consideration are the Mean Residual Life (MRL), which is very important in reliability studies, and Tail Value at Risk (TVaR), which is an important measure of risk in actuarial studies. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…As the next step, comparative physicochemical changes of the native and the mutant proteins were carried out using essential dynamics. …”
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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…It is classified into three categories: D-2-HGA, L-2-HGA, and combined D,L-2-HGA. The D-2-HGA includes two subtypes: type I and type II caused by the mutations in D2HGDH and IDH2 proteins, respectively. …”
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Correlated decay of triplet excitations in the shastry-sutherland compound SrCu2 (BO3)2
Published 2014“…The temperature dependence of the gapped triplet excitations (triplons) in the 2D Shastry-Sutherland quantum magnet SrCu2(BO3)2 is studied by means of inelastic neutron scattering. …”
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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions
Published 2013“…The value of the observed rate constant, k obs, increases with decreasing pH. At constant reaction conditions, the dependence of the observed rate constants, k obs, is described by Eq. (1). kobs = ko + k1 [H+] The dependence of both kand k 1 on [SBr] is not linear. …”
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
Published 2023“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
Published 2021“…Random coefficient models determined relationships between Tc and COX/PGE2. Tc [mean (range)] increased in hot [+ 0.8 (0.4–1.2) °C; p < 0.0001; effect size (ES): 2.9], decreased in cold [− 0.5 (− 0.8 to − 0.2) °C; p < 0.0001; ES 2.6] and was unchanged in thermoneutral [+ 0.1 (− 0.2 to 0.4) °C; p = 0.3502]. …”
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Molecular dynamics of CH4/CO2 on calcite for enhancing gas recovery
Published 2022“…Radial distribution function (RDF) analysis reveals two distinct peaks for CO2 (0.36 and 0.47 nm) and two for methane (0.87 and 0.57 nm) and the intensities of these peaks tend to decrease with increasing temperature. …”
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Impact of SARS-CoV-2 on Ambient Air Quality in Northwest China (NWC)
Published 2021“…The PM2.5 failed to comply in SN and XJ; PM10 failed to comply in SN, XJ, and NX with CAAQS Grade II standards (35 µg/m3, 70 µg/m3, annual mean). …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Missense mutations of the HNF1A were retrieved from public databases and subjected to a three-step computational mutational analysis to identify the underlying mechanism. …”
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Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…The sensing mechanism of the graphene-based sensors can be summarized as follows: exposure of the graphene sensor to Hg2+ ions decreases electron concentration in the n-type graphene, thus, the conductance of the sensor decreases. …”
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Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population
Published 2019“…The effectiveness of dapagliflozin in the management of type-2 diabetes mellitus (T2-DM) is an essential issue for establishing a basis for prescribing dapagliflozin. …”
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Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
Published 2016“…Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …”
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Epidemiology of herpes simplex virus type 2 in Europe: systematic review, meta-analyses, and meta-regressions
Published 2023“…Seroprevalence decreased by 1% per calendar year. Pooled mean proportions of HSV-2 detection in GUD and in genital herpes were 22.0% (95% CI: 15.3–29.6%) and 66.0% (95% CI: 62.9–69.1%), respectively. …”
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