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Decrease of myopia progression with 0.025% atropine
Published 2018“…<p></p><p>Abstract Purpose: To demonstrate the efficacy of 0.025% atropine eyedrops in myopic children in Brazil for decreasing myopia progression Methods: This was a prospective study with 60 children from Hospital Geral Universitário and Oftalmocenter Santa Rosa in Cuiabá, MT, Brazil, aged between 6 to 12 years, with spherical equivalent refractive error of -1.00 to -6.00 diopters (D) and astigmatism of -1.00 D or smaller. …”
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WNT3 decreases GCP proliferation by inhibiting SHH dependent gene transcription.
Published 2013“…(<i>F</i>) After 24 h of GLI1 overexpression in GCPs, <i>Gli2</i>, and <i>Ptch1</i> mRNA levels increase in the control condition (Gli1=464±119, Gli2=2.04±0.25, <i>Ptch1</i>=1.59±0.14) and this effect is inhibited in the presence of WNT3 (Gli1=314±166, Gli2=1.14±0.3, <i>Ptch1</i>=0.71±0.12). …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…<p><b>A,B:</b> Gene knockdown of EZH2 and SUZ12 was confirmed by qPCR. …”
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MK-STYX decreases RhoA activation.
Published 2014“…<p>(<b>A</b>) PC12 cells were transfected with pMT2 or pMT2-FLAG-MK-STYX-FLAG. 24 hr post-transfection cells were stimulated with 100 ng/ml NGF, and lysed at the indicated time points. …”
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Characterization of the optimized nanoparticles (These values are means of a minimum of 5 batches).
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Translocation of EHEC-Hly to mitochondria results in cytosolic cytochrome c release and ΔΨ<sub>m</sub> decrease.
Published 2013“…Mitochondrial cytochrome c signals in control cells (control mito) were almost identical after 8 h, 16 h and 24 h and are therefore shown as means ± standard deviations from all times. …”
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