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_ 12 » _ 2 (Expand Search), _ 1 (Expand Search), _ 10 (Expand Search)
_ decrease » _ decreased (Expand Search), _ decreases (Expand Search), _ decreasing (Expand Search)
h decrease » _ decreased (Expand Search), _ decreases (Expand Search)
_ 12 » _ 2 (Expand Search), _ 1 (Expand Search), _ 10 (Expand Search)
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Adaptive thermal comfort in the different buildings of Darjeeling Hills in eastern India – Effect of difference in elevation
Published 2018“…Whereas, the mean comfort temperature decreased with the elevation of the location and this difference was also statistically significant, t = −92.34 (df = 2607, p < 0.001). …”
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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
Published 2014“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Published 2013“…VEGF-R2 inhibitor reduced the permeability effect of 12-HETE. Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. …”
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Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives
Published 2023“…Introduction: The anticancer and anti-inflammatory activities of a novel series of eleven pyrimido[1,2-b]pyridazin-2-one analogues substituted at position 7 were assessed in the current study. …”
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Chemical characterization and therapeutic properties of Achillea biebersteinii leaf aqueous extract synthesized copper nanoparticles against methamphetamine-induced cell death in P...
Published 2020“…In particular, both doses of CuNPs significantly (p ≤ 0.01) increased cell viability and NO production, and decreased cell cytotoxicity, cell death index, and caspase-3 activity near the normal. …”
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The Effect of Visual Impairment and Its Severity on Vision-Related and Health-Related Quality of Life in Jordan: A Comparative Cross-Sectional Study
Published 2023“…An interviewer administered the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and the Medical Outcomes Study 12-Item Short Form Health Survey (SF-12) to all participants. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …”
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Dose of Bicarbonate to Maintain Plasma pH During Maximal Ergometer Rowing and Consequence for Plasma Volume
Published 2022“…This study evaluated the dose of BIC needed to eliminate the decrease in plasma pH during maximal ergometer rowing and assessed the consequence for change in plasma volume. …”
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Microbial electrosynthesis feasibility evaluation at high bicarbonate concentrations with enriched homoacetogenic biocathode
Published 2020“…The production of acetate induced a change in the catholyte pH, from neutral conditions towards acidic conditions.…”
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Urology Residents' Perspectives on the In-House On-Call Systems: A Study in an Accredited Academic Center
Published 2022“…However, the total number of duty hours violations decreased in the 12-hour on-call system. Conclusion: The 12-hour system is a better alternative to the 24-hour system in terms of the resident's quality of life, education, surgical case volume, and compliance with duty hour rules.…”
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