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Inhibition of MRP1 significantly decreases basal and apoptotic GSH efflux.
Published 2012“…A significant decrease (P<0.001 vs scrambled control) in GSH release was observed in 5 h. …”
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Characterization of the optimized nanoparticles (These values are means of a minimum of 5 batches).
Published 2015Subjects: -
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WNT3 decreases GCP proliferation by inhibiting SHH dependent gene transcription.
Published 2013“…<p>(<i>A</i>) WNT3 decreased proliferation of GCPs by 40.3± 5.0% of the control (Con) (n=3) as measured by [<sup>3</sup>H]-Thymidine incorporation assay. …”
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Exposure to low CO<sub>2</sub> levels decreases ER cholesterol levels.
Published 2023“…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO<sub>2</sub> for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …”
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Transcriptional repression of synapse-related genes and a decrease in spine density by AAV-hGATA1 and AAV-hGATA2 in DG of the rat hippocampus.
Published 2014“…<sup>*</sup><i>P</i><0.05, <sup>**</sup><i>P</i><0.01, <sup>***</sup><i>P</i><0.001 compared to control vector. Values represent mean ± s.e.m. of 5–7 cells from three animals per group. …”
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CC-1<sup>+</sup> immunostained cell numbers decrease by 2 days after TBI and return to control levels by 5 weeks.
Published 2015“…Panels show contralateral (Contra) and ipsilateral (Ipsi) external capsule (EC) at (A,B) 2 days (2d), (C,D) 2 weeks (2w) and (E,F) 5 weeks (5w) (G) In the external capsule numbers of CC-1<sup>+</sup> oligodendrocytes were decreased by 2d after injury, remained decreased at 2 weeks and returned to normal levels by 5 weeks. …”