Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK by Patel, Shivalee

“…Stakeholder interrelations, regulatory and socio-economic aspects are discussed in relation to their influence on decreasing avoidable food waste. The main output from this work is a diagrammatic depiction of where challenges and trade-offs occur along the food supply chain, and how policy and socio-economic reforms are needed to maximise avoidable food waste prevention, and the surplus avoidable food redistribution in the food supply chain for social benefit.…”
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A new family of boost active neutral point clamped inverter topology with reduced switch count by Siddique, Marif Daula

“…A new family of inverter topology for active neutral point clamped (ANPC) is proposed. …”
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Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar by Chemaitelly, Hiam

“…Conclusion The conclusion of the first omicron wave was a turning point in the severity of the pandemic. …”
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Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells by Posadino, Anna Maria

“…Failure of PE to induce PC3 damage in cells overexpressing Akt further confirms its implication in the PE-elicited cell death. …”
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Impact of magnetic dipole on a thermally stratified ferrofluid past a stretchable surface by Muhammad N.

“…This article focuses on the characteristics of a magnetic dipole in a viscous ferrofluid induced by linear stretched surface. …”
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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines by Prabhu K.S.

“…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. …”
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Credit bureaus and financial constraints do corruption matter? by Ben Ali, Mohamed Sami

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Understanding the False Positive of Modified Martensitic Steels in Sweet & Sour Service Conditions Using a Point Defect Model Perspective by Martinez, Alan

“…These results indicate a critical point in temperature in the tests with only CO2, where resistance to pitting susceptibility is maximized due to a decrease in the cation vacancy diffusivity.…”
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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact by Gowid, Samer

“…This paper aims to develop a robust and practical photovoltaic (PV) Maximum Power Point (MPP) identification tool developed using reliable experimental data sets. …”
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway by Anwar, M. Akhtar

“…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem

“…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …”
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Adaptive thermal comfort in the different buildings of Darjeeling Hills in eastern India – Effect of difference in elevation by Thapa, Samar

“…Whereas, the mean comfort temperature decreased with the elevation of the location and this difference was also statistically significant, t = −92.34 (df = 2607, p < 0.001). …”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…An extensive two-step molecular dynamics (simple and complex) simulation (MDS) using GROMACS (GROningen MAchine for Chemical Simulations) was then initiated to analyze and understand the structural impact of the E17K mutation on the function of AKT1. The simple MDS analysis revealed that the E17K mutation decreases the compactness and intramolecular hydrogen bonds of the protein. …”
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Ganji, Vijay

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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway by Hadrich, F.

“…Moreover, the cotreatment of EE 1/1000 or oleuropein with insulin increased considerably the expression of p-IRS, p85-pI3K, and p-AKT. In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. …”
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Locations of Temporary Distribution Facilities for Emergency Response Planning by Pradhananga, Rojee

“…We assume that the individual demands in close vicinity are grouped at so-called aggregated demand points (ADPs). The distribution process initiates from a central supply point (CSP) which is a collection point that continuously acquires the resources and prepares them for distribution. …”
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Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending by MacLean M.

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Generation, performance evaluation and control design of single-phase differential-mode buck-boost current-source inverters by Darwish, Ahmed

“…Yet, the investigation, operation and implementation of these types of inverters have not been extensively discussed. As a drawback, the total dc side input current of a single-phase inverter consists of a dc component and an undesirable ac component. …”
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A Model For A Narrow-Cut Fractionating Column by Farag, Hassan A.

“…A mathematical model was developed to simulate the operation of a narrow-cut fractionating column. …”
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