Treatment adoption and diffusion pattern. by Frédéric Galacteros (11105678)

“…In clinical studies, voxelotor has been shown to increase hemoglobin (Hb) and decrease hemolytic markers in patients with SCD. The objective of this study was to estimate the impact of voxelotor on the burden of SCD in France using a modeling approach, accounting for its anticipated adoption and diffusion over the next 5 years. …”

Data_Sheet_5_Exploring the active ingredients and pharmacological mechanisms of the oral intake formula Huoxiang Suling Shuanghua Decoction on influenza virus type A based on netwo... by Ruying Tang (14036640)

Image3_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Image1_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Table1_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.DOCX by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Image2_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Combustion Characteristics of C₅ Alcohols and a Skeletal Mechanism for Homogeneous Charge Compression Ignition Combustion Simulation by Sungwoo Park (1234614)

“…C₅ alcohol blending in PRF75 in HCCI combustion leads to a significant decrease of low-temperature heat release (LTHR) and a delay of the main combustion. …”

Combustion Characteristics of C₅ Alcohols and a Skeletal Mechanism for Homogeneous Charge Compression Ignition Combustion Simulation by Sungwoo Park (1234614)

“…C₅ alcohol blending in PRF75 in HCCI combustion leads to a significant decrease of low-temperature heat release (LTHR) and a delay of the main combustion. …”

Combustion Characteristics of C₅ Alcohols and a Skeletal Mechanism for Homogeneous Charge Compression Ignition Combustion Simulation by Sungwoo Park (1234614)

“…C₅ alcohol blending in PRF75 in HCCI combustion leads to a significant decrease of low-temperature heat release (LTHR) and a delay of the main combustion. …”

COVID19 effect on essential services. by Admas Abera (11821659)

“…The present study found that the mean number of patients treated for TB declined by 35 patients (β: -34.62; 95%CI: -50.29, -18.95) compared to the pre-COVID-19 era while the number of new patients enrolled for ART decreased by 71 patients (β: -70.62; 95%CI: -107.19, -34.05). …”

General laboratory tests and specific coagulation test in PCR SARS-CoV-2 positive patients with and without thrombosis. by B. de Laat (12475632)

Pre-treatment with GnRHa or <i>ulipristal acetate</i> prior to laparoscopic and laparotomic myomectomy: A systematic review and meta-analysis by Inge de Milliano (4515127)

“…Pre-treatment with GnRHa before laparoscopic myomectomies also shows a reduction in intra-operative blood loss by 23.03ml (95% CI -40.79 to -5.27) and in the frequency of blood transfusions (OR 0.17, 95% CI 0.05 to 0.55) compared to no pre-treatment.…”

Map of Isla Natividad off the coast of North America. by Adam J. Schlenger (10687093)

cART up-regulated iNOS and TNF-α in HIV-Tg rats—Blockade by Mg. by Lama ElZohary (6250859)

pH Dependence of Succinimide-Ester-Based Protein Cross-Linking for Structural Mass Spectrometry Applications by Esben Trabjerg (1540687)

“…DSS was able to cross-link proteins even at pH 4.0, but a clear decrease in the cross-linking efficiency was observed when the pH was lowered. …”

KO of <i>Garin3</i> led to the loss of ADAMs and aberrant ZP-binding ability. by Haoting Wang (16952764)

DataSheet1_MircroRNA Let-7a-5p in Airway Smooth Muscle Cells is Most Responsive to High Stretch in Association With Cell Mechanics Modulation.zip by Kang Wen (7186409)

“…Direct binding between let-7a-5p and ItgαV was also verified in classical model cell line by using dual-luciferase assays.…”

Data of GO analysis. by Haoting Wang (16952764)

“…Here, we generated KO mice of other <i>Garins</i>, namely <i>Garin2</i>, <i>Garin3</i>, <i>Garin4</i>, <i>Garin5a</i>, and <i>Garin5b</i> (<i>Garin2-5b</i>). …”

Sequences used for phylogenetic analyses. by Haoting Wang (16952764)

“…Here, we generated KO mice of other <i>Garins</i>, namely <i>Garin2</i>, <i>Garin3</i>, <i>Garin4</i>, <i>Garin5a</i>, and <i>Garin5b</i> (<i>Garin2-5b</i>). …”

Comparison of sensitivity and specificity of three diagnostic tests to detect <i>Schistosoma mansoni</i> infections in school children in Mwanza region, Tanzania by Antje Fuss (5675879)

“…The POC-CCA test had the highest sensitivity (99.5%) and a specificity of 63.4% by LCA and the real-time PCR test had a sensitivity of 98.7% and the highest specificity (81.2%).…”