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Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring
Published 2016“…Of 2,146 SNPs tested, a rare missense variant in the <i>PTPN5</i> gene (rs56234898; minor allele frequency 1.5%) was significantly associated with decreased severity of post-burn HTS (<i>P</i> = 1.3×10<sup>−6</sup>). …”
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Dexamethasone decreases PGC-1α protein expression and transcription.
Published 2016“…<p>(A) Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased PGC-1α protein expression (p = 0.01). n = 3/treatment from 3 experiments. …”
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Dexamethasone decreases CRTC1 and CRTC2 nuclear localization.
Published 2016“…<p>Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased (A) total CRTC1 (p = 0.004 and CRTC2 protein (p = 0.0007). n = 9/treatment from 3 experiments. …”
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Decreased innervation and decreased epidermal thickness in STZ diabetic rats.
Published 2015“…<p>Decreased density PGP9.5-IR nerve fibers (<b>A</b>) and average epidermal thickness (<b>F</b>) was demonstrated in the plantar skin of diabetic animals 4, 6, and 8 weeks after induction of diabetes (black bars) when compared to control (white bar). …”
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Panel (a) shows ensemble mean global mean near-surface air temperature in historical and RCP simulations from CanESM2
Published 2013“…Shaded bands show estimates of the 5–95% uncertainty ranges in the ensemble mean ratios, derived by taking the standard deviation of the ratio from each of the five independent pairs of simulations with and without aerosol changes, dividing by the square root of five (the ensemble size), and multiplying by a Student-<em>t</em> statistic with a cutoff value of 0.05 and four degrees of freedom (one less than the ensemble size). …”
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Claudin V is decreased following infection with Mtb.
Published 2024“…<p>Immunofluorescent staining of guinea pig brain tissue for DAPI (blue) and claudin V (cyan) in vessels was performed. Representative images of the frontal cortex (A–D), cerebral nuclei (F–I), brain stem (K–N), thalamus (P–S), and hippocampus (U–X) 15 days post-infection are shown. …”
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Decreased expression of adipogenesis-related genes by baicalein in early stage of adipogenesis.
Published 2016“…<p>A, Expression levels of the adipogenic and lipogenic genes. 3T3-L1 cells (undifferentiated cells: U; <i>white columns</i>) were differentiated into adipocytes (differentiated cells: D) for 6 days in DMEM in the absence (<i>gray columns</i>) or presence (50 μM; <i>black columns</i>) of baicalein during days 0–2 or 0–6. …”
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