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Pan-JAK inhibitor P6 decreased ISG expression and increased susceptibility of BEAS-2B cells to H1N1 influenza virus infection.
Published 2014“…BEAS-2B cells were pre-treated with P6 at a final concentration of 2.5 or 5 µM for 24 h and infected with H1N1 influenza virus at 1.0 MOI (based on MDCK cells). …”
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243
Inflammation is not sufficient to account for decreased relative bacterial numbers in higher dose infection.
Published 2012“…D) CCR2 KO animals exhibited a significant decrease in the number of recruited Ly6c+/CD11b+/CD11c+ monocytes at day 9 PI in high dose infection. …”
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Disruption of bacterial K<sup>+</sup> homeostasis decreases Mtb colonization of macrophages.
Published 2019“…Data are shown as means ± SD from 5–6 wells, representative of 3–4 independent experiments. …”
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247
GFRα2 expression was dramatically decreased in Runx1 knockout mice.
Published 2013“…*<i>p</i><0.05; t-test. <b>C</b>) Five days after sciatic nerve axotomy, Runx1 expression decreased in ipsilateral DRG (<b><i>C<sup>/</sup></i></b>) relative to contralateral DRG (<b><i>C</i></b>). …”
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GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…(B) Animals treated with GSK had significantly decreased relative tumor growth compared to those treated with vehicle. …”
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Treatment with anti-JAM-C antibody decreases the severity of antigen-induced arthritis
Published 2011“…Results shown represent the mean ± SEM for anti-JAM-C antibody-treated (= 5 on day 4, = 6 on day 8, black columns) and isotype-matched control antibody-treated (= 5 at both time points, open columns) mice. …”
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253
METH decreased basal pERK1/2 levels and potentiated ERK1/2 phosphorylation induced by 6-OHDA.
Published 2013“…METH decreased activation of ERK 1/2 in a concentration-dependent manner (0, 0.5, and 1 mM at the 24 hr time point) and enhanced the activation of ERK1/2 after 6-OHDA exposure. …”
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Decrease of galectin-3 positive cells in bleomycin-injured lung tissue upon administration of hUC-MSC.
Published 2018“…<p>Macrophage infiltration in mouse lungs at days 8 (<b>A-D</b>) and 21 (<b>E-H</b>) after endotracheal injection of sterile saline (saline) (<b>A, E</b>) or bleomycin (bleomycin) (<b>B, F</b>), the latter also followed by intravenous infusion of hUC-MSC (bleomycin+hUC-MSC) (<b>D, H</b>) or sterile saline (bleomycin+saline) (<b>C, G</b>). …”
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256
Dox-inducible expression of HA-MAD1 in colon is sufficient to decrease p53 expression and cause chromosome missegregation.
Published 2024“…Large circles show mean of cells from 5 fields of view from a single animal. (D) Immunoblot showing p53 protein expression is decreased in colon tissue from 5-month old HA-MAD1 mice after 1 week of 6 mg/kg dox feed as compared to control. …”
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