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Fold change in humoral and cellular response magnitudes from RV305 week 2 to week 26.
Published 2023Subjects: -
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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…<p>(<b>A</b>) Genome-wide expression of 5′ splice sites, 3′ splice sites, and introns are increased relative to exons upon treatment of HeLa cells with isoginkgetin (30 µM, 18 hours), based on total RNA-Seq (dUTP method <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089673#pone.0089673-Parkhomchuk1" target="_blank">[18]</a>, Illumina). …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”
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Demethylation of HPV16 LCR CpG sites decreases E6 and E7 expression.
Published 2015“…<p>Demethylation of the CpG sites induced by 0.5 μM 5-aza-dc for 96 h decreased E6 and E7 expression, which was detected by reverse transcription PCR <b>A)</b> and quantitative real-time PCR <b>B)</b>; E6 and E7 were clearly decreased in UM-SCC47 and CaSki cells, but there was no obvious change in SiHa cells. …”
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Delphinidin alters VEGF-A splicing to increase VEGF-A<sub>165</sub>b and decrease total VEGF-A expression.
Published 2019“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A<sub>165</sub>b relative to total VEGF-A<sub>165</sub> (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A<sub>165</sub>b before stripping and reprobing with panVEGF-A). …”
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Dox-inducible expression of HA-MAD1 in colon is sufficient to decrease p53 expression and cause chromosome missegregation.
Published 2024“…Large circles show mean of cells from 5 fields of view from a single animal. (D) Immunoblot showing p53 protein expression is decreased in colon tissue from 5-month old HA-MAD1 mice after 1 week of 6 mg/kg dox feed as compared to control. …”
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UVB irradiation decreased TM expression in HaCaT cells.
Published 2013“…<p>(A) HaCaT Cells were exposed to UVB irradiation in a dose-response (0, 1.5, 3, 4.5, 6 mJ/cm<sup>2</sup>) Cell viability was examined by trypan blue exclusion. …”