Decreased β-cell mass in Hq mutant mice. by Fabienne T. Schulthess (13268705)

The influence of leucettines as DYRK1A inhibitors on insulin, C-peptide, and glucagon production by MIN6 cells. by Barbara Pucelik (2988795)

Subjects:

ATXN3 depletion decreases PNKP’s 3’-phosphatase activity. by Arpita Chatterjee (529752)

WT1 (+KTS) decreases basal and GnRH-stimulated LHβ promoter activity. by Debalina Bagchi (686046)

Osr1 heterozygous mice experienced decreased bile acid synthesis in the liver. by Ernest C. Lynch (12769954)

“…<p>(A). Osr1 male mice had a decreased trend of hepatic bile acid compared to WT mice. …”

Prolonged exposure to oxidized LDL particles decreases Cx36 levels in β-cells. by Jacques-Antoine Haefliger (134116)

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…<b>C.</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Fig 5 - by P. R. Hut (12152350)

Subjects:

Cellular stress decreases TDP-43 levels in patient neurons with the TDP-43 A90V mutation. by Zhijun Zhang (315079)

Subjects:

Sodium chlorate and heparinase treatment decreases cell fusion. by Mary M. Melia (623496)

Spatial training decreases endogenous PTEN ubiquitination and <i>Pten</i> cKO mice show impaired spatial learning and memory. by Wei-Lun Hsu (1756123)

“…Endogenous PTEN ubiquitination level is decreased in Nedd4 siRNA-transfected rats (t_1,6 = 5.92, <i>p</i> = 0.001). …”

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)

Fig 6 - by P. R. Hut (12152350)

Subjects:

Absence of adaptive immunity decreases tumor cell damage in MDR1A deficiency. by Eva Maria Hennenberg (4234018)

KRAP−/− Mice Showed Decreased Weight-Gain and Decreased Adiposity. by Takahiro Fujimoto (268158)

p35 siRNA knockdown decreased Cdk5 activity, diminished WT1 expression and viable cell numbers, but did not affect a cell apoptosis marker as detected by WB. by Ya-Li Zheng (454837)

“…C. p35 siRNA reduced Cdk5 activity. D. Western blotting analysis showed a decline of WT1 expression in p35 siRNA podocytes (upper panel, lane 2 compared to lane 1, p = 0,048), but did not affect cleaved caspase 3 expression (middle panel, lane 2 compare with lane 1). …”

Dexamethasone decreases CRTC1 and CRTC2 nuclear localization. by Jill A. Rahnert (2872766)

“…<p>Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased (A) total CRTC1 (p = 0.004 and CRTC2 protein (p = 0.0007). n = 9/treatment from 3 experiments. …”

LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

Absence of LFA-1 results in decreased numbers of NKT cells within the regenerating liver. by Ann-Kathrin Jörger (3559358)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA_A-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”