Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring by Ravi F. Sood (263139)

“…Of 2,146 SNPs tested, a rare missense variant in the <i>PTPN5</i> gene (rs56234898; minor allele frequency 1.5%) was significantly associated with decreased severity of post-burn HTS (<i>P</i> = 1.3×10⁻⁶). …”

Decreased responsivity to mechanical stimuli during DRN 5-HT neurons photostimulation. by Guillaume P. Dugué (620333)

Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice by Shohei Ishikawa (4583068)

“…MMP-2 and 9 activity levels in the infarcted myocardium were significantly lower in AIM^{<b>‒/‒</b>} mice than in WT mice.</p><p>Conclusions</p><p>These findings suggest that AIM depletion decreases the levels of M1 macrophages, which are a potent source of MMP-2 and 9, in the infarcted myocardium in the acute phase after MI by promoting macrophage apoptosis, and leads to a decrease in the incidence of cardiac rupture and improvements in survival rates.…”

H-MSCs^WT decrease myofibroblasts in peri-infarction region. by Panpan Chen (307628)

Diabetic wounds show increased amounts of vessel leakage and decreased pericyte coverage. by Uzoagu A. Okonkwo (8754933)

Top 50 genes whose expression is most decreased in PN11 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Top 50 genes whose expression is most decreased in PN56 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Increased endodiastolic volume and decreased ejection fraction in GJB4-deficient zebrafish. by Ryuji Okamoto (614374)

Tear stability is decreased in <i>Muc5ac</i>-deficient mice (KO) compared to wild-type mice (WT). by Anne M. Floyd (293362)

Deletion of TXNIP decreases thioredoxin levels under hyperoxic conditions. by Mohammed A. Abdelsaid (287140)

“…<p>WT and TKO mice were subjected to 5 days hyperoxia (p7–12). …”

Total RNAP II levels decrease during WT HSV-1 KOS infection. by Mark Ou (474248)

Decreased β-cell mass in Hq mutant mice. by Fabienne T. Schulthess (13268705)

ATXN3 depletion decreases PNKP’s 3’-phosphatase activity. by Arpita Chatterjee (529752)

WT1 (+KTS) decreases basal and GnRH-stimulated LHβ promoter activity. by Debalina Bagchi (686046)

Osr1 heterozygous mice experienced decreased bile acid synthesis in the liver. by Ernest C. Lynch (12769954)

“…<p>(A). Osr1 male mice had a decreased trend of hepatic bile acid compared to WT mice. …”

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…<b>C.</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Cellular stress decreases TDP-43 levels in patient neurons with the TDP-43 A90V mutation. by Zhijun Zhang (315079)

Subjects:

Sodium chlorate and heparinase treatment decreases cell fusion. by Mary M. Melia (623496)

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

“…Endogenous Beclin 1 ubiquitination level is decreased in Nedd4 siRNA-transfected rats (t_1,6 = 5.78, <i>p</i> = 0.001). …”

Decreased biofilm formation in the Δ<i>tad123</i> mutant cells. by Tra-My Duong-Nu (7300970)