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6 we » 16 we (Expand Search), _ we (Expand Search), 6 e (Expand Search)
we decrease » nn decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
n decrease » nn decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decreased (Expand Search), _ decreases (Expand Search)
_ decrease » _ decreased (Expand Search)
6 we » 16 we (Expand Search), _ we (Expand Search), 6 e (Expand Search)
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Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction
Published 2015“…Conversely, the expression levels of liver detoxification enzymes, UGT2B4/7, SULT2A1, GSTA1-4, and GSTM1-4, were reduced by approximately 50% (p<0.05) in human obstructive cholestasis. …”
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miR-105 results in decreased Cdk6 expression at both the mRNA and protein levels.
Published 2013“…<p>(A–B) PC3 cells were transfected with 50 nM miR-105 or control mimics as described in materials and methods and relative levels of Cdk6 expression were assessed over time. …”
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Decrease in Vitamin D Status in the Greenlandic Adult Population from 1987–2010
Published 2014“…</p><p>Conclusion</p><p>We identified a remarkable decrease in vitamin D status from 1987 to 2005–2010 and a presently low vitamin D status among Inuit in Greenland. …”
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Loss of fenestrations and decreased VEGF production in <i>Cyp1b1-/-</i> LSEC.
Published 2018“…No significant difference was observed in the mRNA levels of VEGF. A significant decrease in the amounts of Bmp6 mRNA was observed in <i>Cyp1b1-/-</i> LSEC (***P< 0.001; n = 3). …”
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<i>Myotis rufoniger</i> genome sequence and analyses: <i>M</i>. <i>rufoniger’s</i> genomic feature and the decreasing effective population size of <i>Myotis</i> bats
Published 2017“…<i>rufoniger</i>’s red fur color and a general coloration in <i>Myotis</i>. <i>N6AMT1</i> gene, associated with arsenic resistance, showed a high degree of function alteration in <i>M</i>. …”
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Trial profile.
Published 2024“…Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”
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GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)
Published 2017“…Structure–activity relationship studies coupled with further structure-based design targeting the LPF shelf, BC loop, and KAc regions allowed us to significantly increase potency and selectivity, resulting in the identification of non-CNS penetrant <b>19</b> (GNE-781, TR-FRET IC<sub>50</sub> = 0.94 nM, BRET IC<sub>50</sub> = 6.2 nM; BRD4(1) IC<sub>50</sub> = 5100 nΜ) that maintained good in vivo PK properties in multiple species. …”
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Sarcopenia as an Independent Risk Factor for Decreased BMD in COPD Patients: Korean National Health and Nutrition Examination Surveys IV and V (2008-2011)
Published 2016“…<div><p>Background</p><p>A decrease in bone mineral density (BMD) is a systemic consequence of chronic obstructive pulmonary disease (COPD). …”
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A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension
Published 2014“…</p><p>The IC<sub>50</sub> values of ONO-8540506 for lysophospholipase D activity were 6.4–19 nM for recombinant autotaxin/ENPP2 proteins and 4.7–11.6 nM for plasma from various animal species. …”
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Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis
Published 2016“…NRTI TDR decreased (4.5% vs. 2.3%, p<0.0001). NNRTI TDR increase was associated mainly with K101E, K103N and G190A. …”
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Data_Sheet_1_Marathon Running Increases Synthesis and Decreases Catabolism of Joint Cartilage Type II Collagen Accompanied by High-Energy Demands and an Inflamatory Reaction.PDF
Published 2021“…Mean sC2C levels (220.83 ± 39.50 ng/ml) decreased post-race (188.67 ± 38.52 ng/ml) (p = 0.002). …”