Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx. by Orli Snir (18625811)

“…Mean ± SE, <i>n</i> = 3. <i>p</i> > 0.05, Student’s <i>t</i> test. <b>(M)</b> Median fold-change (ether/ctrl) of protein levels in the following subsets of Hsp90 clients (left to right): All clients (<i>n</i> = 280), Hsp90 w/o Trx or Ubx targets (<i>n</i> = 197), Hsp90 and Trx but not Ubx targets (<i>n</i> = 52), Hsp90 and Trx targets (<i>n</i> = 69), Hsp90 and Ubx targets (<i>n</i> = 31), Hsp90 and Trx and Ubx targets (<i>n</i> = 16). …”

Pre-treatment of IOZCAS-Spex-II cells with CPT and HCPT decreased Topo1 specific activity in a time-dependent manner. by Lan Zhang (90951)

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

The catalase enzyme response of <i>A</i>. <i>albopictus</i> larvae decreased (1.5-fold) in response to <i>M</i>. <i>robertsii</i>-derived copper nanoparticles. by Perumal Vivekanandhan (4863484)

Decreased circulating MAIT cell numbers in the peripheral blood of scrub typhus patients. by Seung-Ji Kang (299106)

Rhox5 decreases UNC5C expression. by Mayumi Sugimoto (151133)

Characterization of the optimized nanoparticles (These values are means of a minimum of 5 batches). by Anjuman Arora (750291)

Mutation of four arginine residues in P34 leads to a decrease in binding between P34 and L5. by Anyango D. Kamina (4034165)

3-HPA and the 10-fold diluted reuterin-containing supernatant significantly decreased the <i>S.</i> Typhimurium χ3339 population. by Rosemarie De Weirdt (320666)

DOM assembly monitored with temperature and pH reveals that, as either pH decreases or temperature increases, microgel equilibrium size and assembly rates decrease at a non-linear... by Chi-Shuo Chen (234719)

IFN-β mRNA induction but IFN protein decrease in all mammalian cells upon ONNV infection. by Susanne E. Biesold (194461)

PI+ total immune cells are decreased at days 2, 5, and 14 following IR, and PI+ neutrophils are increased at day 30. by Jordan A. Gunning (18143970)

Subjects:

cDNA sequencing reveals missense point mutations in the UBA3 coding region of MLN4924-resistant K562 cells which decrease the sensitivity of NAE to MLN4924 in vitro. by G. Wei Xu (545673)

HFA decreased expression of osteoclastic markers in alveolar bone. by Mani Alikhani (5180768)

Dispersion-temperature of microgels decreases at lower pHs. by Chi-Shuo Chen (234719)

“…Dispersion temperature dropped ~2˚C with a 0.2 pH decrease. Each data point represents mean (+/−SD) of six measurements made in each of six replicate samples.…”

Mcl-1 protein expression is decreased by internal dsRNA and its modulation regulates beta cell apoptosis. by Maikel L. Colli (179059)

Distribution of miRs with a greater than two fold-change. by Stephanie L. Samani (17896610)

Subjects:

Conditional depletion of RPS0A significantly decreases translation initiation rates. by Tomáš Kouba (153719)

Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain. by Caio Maximino (100467)

“…A negative correlation is found between the decrease in serotonin turnover and the increase in time on white produced by a drug (r² = 0.5688, p = 0.0073).…”

The 5’SS motif decreases mRNA stability and promotes nuclear retention. by Eliza S. Lee (715538)

“…Note that the relative level of <i>c-ftz-Δi-V5-His</i> decreases over the first 60 min until 40–50% of the mRNA remains, after which point the ratio is stable. …”