Myelin decreases ⁵⁵Fe uptake by MDMs. by Veela Mehta (390027)

Real-time PCR confirmation of randomly selected genes whose expression levels were either increased (red) or decreased (green) by a specific endoxifen concentration. by John R. Hawse (227611)

Representative case from ex vivo experiments with core specimens of breast tissue included in the microcalcification group (case #2). by Ga Ram Kim (621106)

The effects of purified cardiac leiomodin2 on actin assembly dynamics. by Dávid Szatmári (4510156)

Comparison of pre-treatment and post-treatment fluorescence imaging in orthotopic LS174T mouse models. by Hannah M. Hollandsworth (8992103)

K13 shows an increased association with the mitochondria post DHA pulse. by Nina F. Gnädig (8735760)

The <i>P</i>. <i>falciparum</i> artemisinin resistance determinant K13 localizes to the parasite ER and intracellular vesicles. by Nina F. Gnädig (8735760)

Induction of Cell Death by Ternary Copper(II) Complexes of l-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity by Sethu Ramakrishnan (2081944)

“…All of the complexes display a ligand field band in the visible region (600−700 nm) in Tris−HCl/NaCl buffer (5:50 mM) at pH 7.2 and also axial EPR spectra in acetonitrile at 77 K with <i>g</i>_∥ > <i>g</i>_⊥ indicating a d<i>_x</i>_{²−<i>y</i>²} ground state. …”

NGAL-R mediates apical-to-basolateral transcytosis of PC3, MT and Tf in confluent Caco-2 BBE cell monolayers. by Christian Langelueddecke (441233)

Apyrase treatment removes extracellular ATP. by Isabel R. Orriss (432214)

“…<p>(<b>A</b>) Within one minute of 0.5U/ml apyrase treatment, a rapid decrease in ATP levels was observed; by 2 minutes and for the remainder of the experiment (10 minutes) ATP levels were negligible. …”

The CCDC66 depletion disrupts normal tissue organization and signaling in 3D and 2D cultures. by Jovana Deretic (13113617)

“…Mean cilia percentage is 59.78 for shControl and 53.80 for shCcdc66, with a fold change decrease of 0.90. …”

Data_Sheet_2_Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.pd... by Zsófia Onódi (839184)

“…</p><p>Results: The highest band intensities of EV markers Alix, Tsg101 and CD81 were detected by Western blot in F6 of small-scale DGUC (61.5 ± 10.4%; 48.1 ± 5.8%; 41.9 ± 3.8%, respectively) at a density of 1.128–1.174 g/mL, where the presence of vesicles with a mean diameter of 38 ± 2 nm was confirmed by EM and DLS. …”

Data_Sheet_1_Isolation of High-Purity Extracellular Vesicles by the Combination of Iodixanol Density Gradient Ultracentrifugation and Bind-Elute Chromatography From Blood Plasma.pd... by Zsófia Onódi (839184)

“…</p><p>Results: The highest band intensities of EV markers Alix, Tsg101 and CD81 were detected by Western blot in F6 of small-scale DGUC (61.5 ± 10.4%; 48.1 ± 5.8%; 41.9 ± 3.8%, respectively) at a density of 1.128–1.174 g/mL, where the presence of vesicles with a mean diameter of 38 ± 2 nm was confirmed by EM and DLS. …”

An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing by Raymond W. Wong (8463498)

“…<div><p>The ability of HIV-1 to evolve resistance to combined antiretroviral therapies (cARTs) has stimulated research into alternative means of controlling this infection. We assayed >60 modulators of RNA alternative splicing (AS) to identify new inhibitors of HIV-1 RNA processing—a segment of the viral lifecycle not targeted by current drugs—and discovered compound N-[4-chloro-3-(trifluoromethyl)phenyl]-7-nitro-2,1,3-benzoxadiazol-4-amine (5342191) as a potent inhibitor of both wild-type (<i>Ba-L</i>, <i>NL4-3</i>, <i>LAI</i>, <i>IIIB</i>, and <i>N54</i>) and drug-resistant strains of HIV-1 (IC₅₀: ~700 nM) with no significant effect on cell viability at doses tested. 5342191 blocks expression of four essential HIV-1 structural and regulatory proteins (Gag, Env, Tat, and Rev) without affecting total protein synthesis of the cell. …”