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742 a » 72 a (Expand Search)
marked decrease » marked increase (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
742 a » 72 a (Expand Search)
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(A) Auxiliary marking points to ensure complete and accurate seating of the prosthesis.
Published 2025Subjects: -
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Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement
Published 2025“…Decreasing lipophilicity led to the discovery of <b>NP3-742</b>, demonstrating a favorable overall profile including diminished hERG inhibition and in vivo efficacy in a mouse peritonitis model.…”
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Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement
Published 2025“…Decreasing lipophilicity led to the discovery of <b>NP3-742</b>, demonstrating a favorable overall profile including diminished hERG inhibition and in vivo efficacy in a mouse peritonitis model.…”
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Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement
Published 2025“…Decreasing lipophilicity led to the discovery of <b>NP3-742</b>, demonstrating a favorable overall profile including diminished hERG inhibition and in vivo efficacy in a mouse peritonitis model.…”
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S1 File -
Published 2025“…Following the overexpression of miRNA 221 in myocardium, there was a marked alleviation of myocardial injury and cardiomyocyte apoptosis and necrosis, significant enhancement of left ventricular systolic function, and marked decrease in the levels of PLB, p-PLB (Ser16), p-PLB (Thr17), caspase 3 and Cyt C, as well as a significant decrease in total calcium levels in myocardium.…”