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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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GSK343 decreased neuroblastoma viability, proliferation, and motility.
Published 2021“…<p>(A) SK-N-AS, SK-N-BE(2), SH-EP and WAC(2) cells (1.5 × 10<sup>3</sup> cells) were treated with increasing concentrations of GSK343 (0, 5, 15, 25 μM) for 24 hours and viability was measured using alamarBlue<sup>®</sup> assay. …”
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MMR mutants show decreased mating-type silencing.
Published 2020“…<i>sir1Δ</i> mutant was used as a positive control. <b>(D)</b> Cells of indicated strains were 10-fold serially diluted and then spotted onto SC (left), SD-Ura (middle) and SC+FOA(right) agar plates, the <i>sir1Δ</i> mutant served as a positive control. …”
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