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Genes whose expression was decreased by 100 nM ouabain by more than 1.3-fold.
Published 2019“…<p>Genes whose expression was decreased by 100 nM ouabain by more than 1.3-fold.</p>…”
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Genes whose expression was decreased by 1 mM ouabain by more than 2-fold.
Published 2019“…<p>Genes whose expression was decreased by 1 mM ouabain by more than 2-fold.</p>…”
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Repetitive stress induces a decrease in sound-evoked activity.
Published 2025“…These mice exhibited a minimal change in noise-evoked PPy activity when comparing the first and second week of imaging (2-way ANOVA, F = 1.79, <i>p</i> = 0.11, post hoc baseline w1 50 dB: baseline w2 50 dB <i>p</i> = 1 Bonferroni corrected, nested ANOVA (mouse nested within session) F = 1.76, <i>p</i> = 0.12, mean ± SE). …”
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AMPs are increased in lesional HS, but DCD and other sweat-gland associated proteins are decreased.
Published 2019“…Genes represented in red are upregulated by >2-fold in HS lesional skin (p-adj < 0.05). Genes represented in blue are downregulated by >2-fold in HS lesional skin (p-adj < 0.05). …”
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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The decrease or inhibition of Hsp90 induced REST degradation.
Published 2019“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”
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Decreased myofibroblasts in the peritumoral region and high expression of MMP-7 in Pan02 S.C. tumor of <i>S100a4-Cre; Ext1</i><sup><i>f/f</i></sup> mice.
Published 2023“…Scale bar = 50 μm. (D) Microarray analysis of Pan02 S.C. tumor of <i>S100a4-Cre; Ext1</i><sup><i>f/f</i></sup> and control mice (N = 4 for each cohort). …”