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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. Male and female KO and WT mice were fed a HF diet (45% kcal fat) for 16 weeks. …”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. Our findings suggest that direct activation of GLP-1R by Ex-4 reduces OA-induced steatosis in HepG2 cells by reducing fatty acid uptake and transport via FABP1 downregulation.…”
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The Aftermath Of COVID-19 on Grade 9 and 12 Biology Classes in Lebanon
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masterThesis -
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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The new accounting standard IFRS 9 and its impact on how banks should provision for credit losses
Published 2019“…The dissertation is based on qualitative approach where set of interviews with finance and corporate teams of banks and other entities have been contacted. Using semi-structured interviews, respondents were asked to answer the study questions and how banks should provision for expected credit losses under new accounting rule IFRS 9. …”
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Genetic engineering to enhance microalgal-based produced water treatment with emphasis on CRISPR/Cas9: A review
Published 2023“…Bioremediation using microalgae has received increased interest as a method for produced water treatment for removing not only major contaminants such as nitrogen and phosphorus, but also heavy metals and hydrocarbons. …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…Logistic regression was used to determine the risk of stroke associated with PCI among patients with LVT, and a p-value<0.05 indicated statistical significance.…”
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…The problem is modelled using a mixed integer program (MIP) in which the charging time of an EB is pertinent to the battery’s state-of-charge level. To be able to solve large problem instances corresponding to real-world applications of the model, a metaheuristic approach is investigated. …”
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Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases
Published 2006“…Oxaliplatin was associated with sinusoidal dilation compared with no chemotherapy (18.9% v 1.9%, respectively; P < .001; odds ratio [OR] = 8.3; 95% CI, 2.9 to 23.6). …”
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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome
Published 2020“…Lung metastasis assay in mice was used to determine the physiological significance of G9a.…”
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Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods
Published 2025Get full text
doctoralThesis -
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
Published 2013Get full text
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masterThesis -
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