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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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2
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …"
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3
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
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4
Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers
منشور في 2022"…The modified converter contains mainly-one diode, two capacitors, and Coupled Inductor (CI). …"
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5
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
منشور في 2017"…The global increase in the number of adults with raised blood pressure is a net effect of increase due to population growth and ageing, and decrease due to declining age-specific prevalence. …"
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6
Coalition game theoretic P2P trading in a distribution network integrity-ensured local energy market
منشور في 2023"…This paper presents a peer-to-peer (P2P) trading-enabled local energy market (LEM) mechanism and analyses it in the Australian market context to verify its feasibility. …"
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7
Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor
منشور في 2024"…This study investigates carbon deposition during methane dry reforming over a nickel-based catalyst supported on alumina in a laboratory-scale fixed-bed reactor. …"
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8
Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…The rate of HAP-attributable DALYs was higher for males (1530·5, 1023·4–2263·6) than for females (1318·5, 866·1–1977·2). Approximately one-third of the HAP-attributable burden (518·1, 410·1–641·7) was mediated via short gestation and low birthweight. …"
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9
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
منشور في 2025"…ResultsThe base-case analysis projected that CVD in T2D would result in an estimated 2,096,536 PALYs (95 % confidence interval, 1,689,272–2,182,939), contributing US$225.46 (95 %CI, 1,689,272–2,182,939) billion to the country's GDP. …"
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10
Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…Salinity-normalized (to S = 40) total alkalinity (NTA) and dissolved inorganic carbon (NDIC) in surface seawater decrease as waters flow north from Hormuz. The slope suggests that removal of C as CaCO3, organic matter (CH2O) or gas exchange (FCO2) is occurring with a ratio of ΔCaCO3/(ΔCH2O or FCO2) = 1:2.86. …"
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11
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
منشور في 2025"…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …"
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12
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
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13
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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14
Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
منشور في 2023"…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. …"
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15
Ultra-low thermal conductivity in scheelite and A-deficient scheelite ceramics
منشور في 2021"…BaMoO ceramic has shown a decrease in thermal conductivity from 0.8 W m K to 0.65 W m K from 400 K to 650 K. …"
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16
Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture
منشور في 2018"…A series of photomagnetic coordination polymer core-shell heterostructures, based on the light-switchable RbaCob[Fe(CN)6]c·mH2O (RbCoFe-PBA) as core with the isostructural KjNik[Cr(CN)6]l·nH2O (KNiCr-PBA) as shell, are studied using temperature-dependent powder X-ray diffraction and SQUID magnetometry. …"
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17
Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
منشور في 2024"…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). …"
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18
Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
منشور في 2024"…Increasing asymptomatic treatment coverage among FSWs from 0 % to 50 % decreases prevalence from 8.2 % to 0.4 %, 0.6 % to 0.1 %, and 0.2 % to 0.0 %, respectively, with very low prevalence when coverage exceeds 50 %. …"
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Energy saving potential analysis applying factory scale energy audit – A case study of food production
منشور في 2023"…This has allowed a reduction in energy use of up to 18%. The CO2 harmful emissions were also decreased. Additionally, it is estimated that switching from the proposed motors to energy-efficient motors will cost less overall over time, saving around 3472.314 JD/month or 0.33576/year on average. …"
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20
Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach
منشور في 2023"…Microbial profiling of each successive stage revealed lower abundance of eukaryotic organisms, whereas bacterial abundance increased notably resulting in a significant decrease in Tetraselmis sp. abundance. …"
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