Wild type <i>Shigella</i> induce TEER decrease in Caco2 cell monolayers independent of MOIs. by Maria Fiorentino (320647)

JNJ26993135 + BML-111 decreases permeability and enhances ZO-1 and claudin-1 induced by PAF but does not change TEER. by Kameljit K. Kalsi (16496511)

IL-18 increases expression of MLCK and pMLC via ROCK, and decreases that of phosphorylated STAT-5. by Ossama Allam (5043434)

Transepithelial resistance of NHBE decreases significantly after PAA exposure. by Ellie S. Burns (21246537)

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

A decrease in the invasiveness of <i>Candida albicans</i> into Caco-2 cells parallels the differentiation of intestinal epithelial cells. by Marianne Goyer (2550589)

“…Caco-2 cell differentiation increased throughout the culture as highlighted by the increase in TEER measurements (Ω.cm²) (full line), which correlated with a decrease in <i>C</i>. …”

IL-18 induces death in HT-29 cells. by Ossama Allam (5043434)

HBMEC barrier function is not altered by THP-1/IE co-culture supernatants. by Janet Storm (37473)

The effect of HA digestion and HA replenishment alone or with CS on barrier function measured by TEER. by Charlotte J. van Ginkel (20790466)

Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function by Janet Storm (8266991)

“…</div><div><br></div><div>The files are as follows:</div><div><div><b>-Combined analysis data for fig 2_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig5_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig6_TEER_includes normalisation.csv</b></div><div><b>-Data for fig2A+B+C_TEER_EA cells+inhibitors+thrombin_3.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_1.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_2.csv</b></div><div><b>-Data for fig3_flow cytometry HBMEC.csv</b></div><div><b>-Data for fig4A_TEER_aPC+thrombin_all time points shown.csv</b></div><div><b>-Data for fig4B_TEER_RBC+IE+lysate_all time points shown.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#04-2+#91-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#91-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-1+#04-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-1.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-3.csv</b></div></div><div><br></div><div>The related publication investigated the hypothesis that the Thrombin-PAR1 coagulation/inflammation axis plays a significant role in barrier loss in cerebral malaria (CM), and that adjunct treatments targeting this might alleviate mortality or post-CM neurological sequelae in CM. …”

DENV2 but not WNV NS1 binding to endothelial cells induces endothelial barrier dysfunction. by Henry Puerta-Guardo (400106)

“…All DENV2 NS1 concentrations induce statistically significant decreases in TEER (p<0.0001).</p>…”

DENV2 NS1 increases the surface staining of syndecan-1 in the EGL of HPMEC. by Henry Puerta-Guardo (400106)

“…All concentrations of syndecan-1 induce significant decreases in TEER value (10 ng/ml: p <0.05; 20 ng/ml, 50 ng/ml: p<0.0001). …”

DENV NS1-induced effects on the EGL leading to endothelial hyperpermeability are similar across all four DENV serotypes. by Henry Puerta-Guardo (400106)

“…<p><b>(A)</b> TEER assay to evaluate the effect of NS1 proteins from DENV1-4 and WNV (5 μg/ml) on HPMEC endothelial permeability. …”