A potential therapeutic agent for sickle cell anaemia by Nature Research (16552612)

“…<p>Sickle cell anaemia is an inherited disease in which red blood cells become rigid and change from the normal disc shape characteristic of these cells into a sickle-like shape. These abnormally shaped cells stack together and can obstruct small blood vessels, leading to severe pain and tissue damage. …”

Cure of Hookworm Infection with a Cysteine Protease Inhibitor by Jon J. Vermeire (154661)

“…Consistent with its mechanism of action, K11777 decreased by >95% the resident CP activity in parasites harvested from hamsters 8 h post-treatment with a single 100 mg/kg oral dose.…”

Replication and Active Partition of Integrative and Conjugative Elements (ICEs) of the SXT/R391 Family: The Line between ICEs and Conjugative Plasmids Is Getting Thinner by Nicolas Carraro (650366)

“…However, deletion of either the relaxase-encoding gene <i>traI</i> or the origin of transfer (<i>oriT</i>) led to a dramatic increase of R391 loss correlated with a copy number decrease of its plasmid-like form. …”

The relationship between ratings of perceived exertion (RPE) and relative strength for a fatiguing dynamic upper extremity task: A consideration of multiple cycles and conditions by Zahra Vahedi (10838733)

“…For the first 45-min period, there were no significantly different correlations between RPE and relative strength across conditions (average r = −0.62 (standard deviation = 0.38); <i>p</i> = 0.57). There was a significant decrease in average correlation for the second work period (r = −0.39 (0.53)). …”

Genetic context and molecular phylogenetic analysis of SrpM. by Nicolas Carraro (650366)

Endothelial cell development impaired in miR-24 knockdown embryoid bodies. by Lynn Roy (687524)

“…The decrease in class 4 sprouts observed in miR-24 knockdown clones, 24–1, and 24–6B compared to RW4, and SCR shRNA control clones is significant with a P value <0.002. …”

Image1_Case report: Clinical, genetic and immunological characterization of a novel XK variant in a patient with McLeod syndrome.JPEG by Christine Anna Dambietz (19455118)

“…KEL gene expression was examined by RNA sequencing.</p><p>Results: A novel hemizygous frameshift deletion in the XK gene resulting in premature termination of the amino acid chain was identified in a 46-year old male presenting with decrease in physical performance and persisting fatigue after COVID-19 infection. …”

Supplementary file 1_Early life predictors of child development at kindergarten: a structural equation model using a longitudinal cohort.docx by Sarah E. Turner (8478309)

“…Higher SES was related to a-0.26 (p-value =0.01) standardized decrease of EDI vulnerability, and this link was partially mediated through family stress at 3 years (10.6% mediated). …”

Table1_Case report: Clinical, genetic and immunological characterization of a novel XK variant in a patient with McLeod syndrome.XLSX by Christine Anna Dambietz (19455118)

“…KEL gene expression was examined by RNA sequencing.</p><p>Results: A novel hemizygous frameshift deletion in the XK gene resulting in premature termination of the amino acid chain was identified in a 46-year old male presenting with decrease in physical performance and persisting fatigue after COVID-19 infection. …”

DataSheet1_A century of anthropogenic river alterations in a highly diverse river coastal basin: Effects on fish assemblages.docx by Diego Moraga (13798645)

“…Studies in the northern hemisphere have shown that the effects of urbanization on fish assemblages include decrease and/or loss of diversity and abundance of native species, and a proliferation of tolerant exotic species. …”

Data_Sheet_1_Temporary Salt Lakes: Ecosystem Services Shift in a Ramsar Site Over a 50-Year Period.DOCX by Ioanna Ioannidou (11034120)

“…This study examines spatiotemporal LULC changes in a Ramsar coastal temporary wetland (Larnaca Salt Lake) on the island of Cyprus between 1963 and 2015. …”

Identification of Cellular Targets of MicroRNA-181a in HepG2 Cells: A New Approach for Functional Analysis of MicroRNAs by Jane Yi Lin Tan (728488)

“…<i>In vivo</i> luciferase assay further confirmed the positive miR-181a:mRNA bindings, where a significant decrease in luciferase activity was detected when HepG2 cells were co-transfected with the 3’UTR-containing reporter plasmids and miR-181a. …”

Antihypertensive treatment and blood pressure trends among South African adults: A repeated cross-sectional analysis of a population panel survey by Annibale Cois (3229185)

“…<div><p>Background</p><p>Recent findings suggest a decline in mean blood pressure and prevalence of uncontrolled hypertension in the South African adult population in the last decade, in contrast with the increase previously observed. …”

Table_1_Early post-surgical rehabilitation and functional outcomes of a traumatic ulnar nerve injury: a pediatric case report.DOCX by Federica Fulceri (6020525)

“…Of considerable interest, the patient regained a complete functional recovery with satisfactory handgrip and pinch functions in addition with a decrease of disability in activities of daily living.…”

DataSheet_1_A critical analysis of the current TNM classification for differentiated thyroid carcinoma in young patients: Time for a change?.zip by Wenlong Wang (501114)

“…Moreover, Kaplan–Meier survival analysis showed that the 10-year CSS of stage II disease in younger patients with DTC showed a sharp decrease compared with that in older patients with DTC (74.47% vs. 98.43%, P < 0.001). …”

DataSheet1_A century of anthropogenic river alterations in a highly diverse river coastal basin: Effects on fish assemblages.docx by Diego Moraga (13798645)

“…Studies in the northern hemisphere have shown that the effects of urbanization on fish assemblages include decrease and/or loss of diversity and abundance of native species, and a proliferation of tolerant exotic species. …”

DataSheet1_The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model.docx by Hanne Van Spaendonk (11017887)

“…The serine protease inhibitor UAMC-00050 ameliorated both the inflammatory parameters and the intestinal barrier function. Furthermore, a decrease in colonic mRNA expression of Tbet and PAR4 was observed in colitis mice after UAMC-00050 treatment.…”

Impact of a Partial Smoke-Free Legislation on Myocardial Infarction Incidence, Mortality and Case-Fatality in a Population-Based Registry: The REGICOR Study by Fernando Agüero (276046)

“…</p> <h3>Conclusions</h3><p>The 2006 Spanish partial smoke-free legislation was associated with a decrease in population AMI incidence and mortality, particularly in women, in people aged 65–74 years, and in passive smokers. …”

Quantitatively describing the downstream effects of an abrupt land cover transition: buffering effects of a forest remnant on a stream impacted by cattle grazing by Rafael Feijó-Lima (5666879)

“…A decrease in fine sediment size started 386  m below the transition. …”

Table_2_Combining an Ecological Experiment and a Genome Scan Show Idiosyncratic Responses to Salinity Stress in Local Populations of a Seaweed.xlsx by Alexandra Kinnby (6801212)

“…Furthermore, populations responded very differently to a salinity decrease of four practical salinity units (psu) corresponding to projected future salinity. …”