Image_4_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIFF by Jian Wu (41301)

“…<p>A comprehensive understanding of the dynamic changes in interleukin-6 (IL-6) levels is essential for monitoring and treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). …”

Image_1_Striate Artery Infarct After Bilateral Carotid Artery Ligation (BCAL) in a Dog: A Multimodal MRI Study.TIFF by Lukas Komornik (9394952)

“…Multimodal brain MRI including morphologic sequences, MR angiography, diffusion- and perfusion-weighted images were performed. MRI revealed a well-defined intra-axial lesion of the left caudate nucleus, with increased T2 and decreased T1 signal intensity and moderate heterogeneous peripheral contrast enhancement. …”

Adherence to treatment guideline recommendations for Parkinson’s disease in Japan: A longitudinal analysis of a nationwide medical claims database between 2008 and 2016 by Masahiko Suzuki (355352)

“…Combination therapy with L-dopa, non-ergot DA, and monoamine oxidase-B inhibitors was gradually increased at a later stage.</p><p>Conclusion</p><p>These results highlight that the state of PD treatment in Japan adheres to most of the recommendations in the 2011 national guidelines, but also precedes the 2018 guidelines.…”

Table_1_FAM53A Affects Breast Cancer Cell Proliferation, Migration, and Invasion in a p53-Dependent Manner.docx by Jie Zhang (64655)

“…In the p53 wild-type breast cancer cell line MCF-7, FAM53A overexpression inhibited cell migration, invasion, and proliferation, downregulated the expression of Snail, cyclin D1, RhoA, RhoC, and MMP9, and decreased mitogen-activated protein kinase kinase (MEK) and extracellular-signal regulated kinase (ERK) phosphorylation. …”

Coordinated Transcriptome and Metabolome Analyses of a Barley <i>hvhggt</i> Mutant Reveal a Critical Role of Tocotrienols in Endosperm Starch Accumulation by Zhanghui Zeng (3571331)

“…Previously, we generated a tocotrienol-deficient <i>hvhggt</i> mutant with shrunken barley grains. …”

Audio_8_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

“…Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. …”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

“…Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p<0.01); and decreased EphA2 mRNA and protein expression levels (p<0.01), as well as ERK1 and SRF protein expression levels (p<0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). …”

Audio_5_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

“…Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. …”

An Intron Mutation in the <em>ACVRL1</em> May Be Associated with a Transcriptional Regulation Defect in a Chinese Family with Hereditary Hemorrhagic Telangiectasia by Qian Yu (127062)

“…<div><p>Purpose</p><p>To identify a novel pathogenic gene mutation present in a Chinese family with hereditary hemorrhagic telangiectasia (HHT) and to determine if an intron mutation may influence the transcriptional activity of the <i>ACVRL1</i> gene.…”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

“…Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p<0.01); and decreased EphA2 mRNA and protein expression levels (p<0.01), as well as ERK1 and SRF protein expression levels (p<0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). …”

DataSheet_1_AKR1B10 as a Potential Novel Serum Biomarker for Breast Cancer: A Pilot Study.pdf by Zhe Cao (688109)

“…After surgical removal of primary tumors, the serum AKR1B10 was rapidly decreased within 3 days and plateaued at a level similar to that of healthy controls in most patients. …”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

“…Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p<0.01); and decreased EphA2 mRNA and protein expression levels (p<0.01), as well as ERK1 and SRF protein expression levels (p<0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). …”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

“…Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p<0.01); and decreased EphA2 mRNA and protein expression levels (p<0.01), as well as ERK1 and SRF protein expression levels (p<0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). …”

Audio_2_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

“…Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. …”

Audio_7_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

“…Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. …”

Audio_4_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

“…Song complexity appeared to follow the trend of song progression; songs became more complex as they evolved over the months in 2018 and decreased in complexity between the years, returning to a more simplified song in 2019. …”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

“…Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p<0.01); and decreased EphA2 mRNA and protein expression levels (p<0.01), as well as ERK1 and SRF protein expression levels (p<0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). …”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

“…Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p<0.01); and decreased EphA2 mRNA and protein expression levels (p<0.01), as well as ERK1 and SRF protein expression levels (p<0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). …”

A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort by Yong-Hong Zhang (102903)

“…<div><p>Objective</p><p>Human Immunodeficiency Virus (HIV) and Hepatitis C virus (HCV) co-infection is recognized as a major cause of morbidity and mortality among HIV-1 infected patients. …”

Image_2_FAM53A Affects Breast Cancer Cell Proliferation, Migration, and Invasion in a p53-Dependent Manner.JPEG by Jie Zhang (64655)

“…In the p53 wild-type breast cancer cell line MCF-7, FAM53A overexpression inhibited cell migration, invasion, and proliferation, downregulated the expression of Snail, cyclin D1, RhoA, RhoC, and MMP9, and decreased mitogen-activated protein kinase kinase (MEK) and extracellular-signal regulated kinase (ERK) phosphorylation. …”