Interactions of CdiA-CT/CysK and CdiI studied using ITC and SPR. by Soni Kaundal (3148707)

“…(B) SPR data also suggests high affinity as a consequence of decreased dissociation rate. Both raw sensograms (black line) and fitted curves (red line) are shown in the figure. …”

The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice by Yoshinobu Yokoyama (836840)

“…HBV genotype C is the most common genotype in Japan, although the incidence of HBV genotype A is increasing. The reason underlying the differences in viral multiplication of the HBV genotypes is unclear, especially <i>in vivo</i>. …”

Effects of 5-Aza-dc and alcohol on DNMTs and Ntf3/TrkC expressions in the mPFC. by Xiaomeng Qiao (3139755)

“…<p>Fig 5A shows representative immunoblots and total protein image. 5-Aza-dc decreased the protein level of DNMT1 (B), whereas it reversed the alcohol-induced overexpression of DNMT3A (C) and DNMT3B (D). 5-Aza-dc prevented the Ntf3 reduction induced by chronic alcohol exposure (E) but had no effect on TrkC (F). …”

Amplitude of low-frequency fluctuation (ALFF) maps showing significant differences between the botulism patients and the healthy controls. by Ge-Fei Li (6019223)

“…<p>a) ALFF maps of each group were obtained using one-sample <i>t</i>-tests (p < 0.001 and FWE-corrected to p < 0.02 at the cluster level). …”

Proposed model for the dual role of CysK in UPEC536 mediated CDI. by Soni Kaundal (3148707)

“…Binding of CysK to CdiA-CT stabilizes CdiA-CT/CdiI immunity complex, primarily by decreasing dissociation rate, to prevent autoinhibition in UPEC536 inhibitor cells.…”

Morphological, functional and epistatic effects of <i>ninl</i> and <i>dzank1</i> knockdown in zebrafish retina. by Margo Dona (816015)

“…(h) Quantification of Outer Segment length, shown as a scatter graph where each datapoint represents the mean OS length in one larva, revealed a significantly decreased length of outer segments in <i>ninl</i> (2ng/nl), <i>dzank1</i> (6ng/nl) and <i>ninl/dzank1</i> double morphants as compared to controls. …”

Genetic perturbation analysis of the stoichiometry control system. by Koji Ishikawa (703501)

“…<p>(<b>A</b>) Protein-level dosage compensation predominantly targets subunits of multiprotein complexes. …”

Likelihood (log odds) of having malnutrition (SGA 4&5 vs 7) with respect to various BIA parameters. by Hyunjin Ryu (834646)

“…On the contrary, log odds decreased with PhA_LE increased. BIA; bioelectrical impedance analysis, ECW/TBW_WB; ratio of extracellular water to total body water of whole-body, ECW/TBW_TR; ratio of extracellular water to total body water of trunk, ECW/TBW_LE; ratio of extracellular water to total body water of lower extremities, PhA_LE; Phase angle of lower extremities, SGA; subjective global assessment.…”

Regional homogeneity (ReHo) maps showing significant differences between the botulism patients and the healthy controls. by Ge-Fei Li (6019223)

“…<p>A) ReHo maps of each group were obtained using one-sample <i>t</i>-tests (p < 0.001 and FWE-corrected to p < 0.02 at the cluster level). …”

Effect of anti-epileptic drugs on the survival of patients with glioblastoma multiforme: A retrospective, single-center study by Jae Yeoul Ryu (8066999)

“…Some antiepileptic drugs (AEDs) exhibit antitumor effects and could decrease the mortality of patients with GBM. …”

RhoA signaling contributed to the JNK-regulated cell differentiation and migratory polarity formation. by Jiao Luo (156722)

“…(C) After 10 h with SP600125 treatment, cell immunofluorescence of GM130 for the cells along the scratch line were analyzed, and RhoA Q63L could partly rescue SP600125-regulated decreased of mDPCs polarity formation. …”

Stability of Afsup. by Gabriele Sass (335744)

“…<p>A: Mixtures (25%) of freshly prepared 10AFsup in RPMI were kept at 4°C, or heated to 56°C or 90°C for 30 minutes, or subjected to 3 freeze-thaw cycles. …”

Confirmation of miRNA level by RT-qPCR. by Qin-Min Ge (3838885)

“…<p>Relative expression of each miRNA was normalized to hsa-miR-423-5p level. miR-142-5p, miR-22-3p, miR-191-5p, miR-23a-3p and miR-4456 were significantly decreased in both the sepsis-induced AKI and sepsis-non AKI groups compared with the healthy controls. miR-4270, miR-4321 and miR-3165 were obviously increased in the sepsis-induced AKI, and miR-3165 also was obviously increased in sepsis-non AKI group compared with the healthy controls. …”

KDM2A-SF and KDM2B-SF bind to the repressed axin 2 and cyclin D1 promoter regions. by Dijana Lađinović (9565428)

“…</b> The levels of H3K4me3 on the <i>AXIN2</i> promoter rose after the treatment with BIO and then decreased in the presence of the KDM2A isoforms. <b>D.…”

Edited P19 cells exhibited higher β-catenin/TCF transcription, as well as increased survivin/BIRC5 expression. by Masaya Ono (233238)

“…<p>A. Edited P19 cells exhibited significantly higher β-catenin/TCF transcription compared with wild type (WT) cells under basal conditions, as assessed by Topflash/Fopflash (TOP/FOP) activity. n = 3, *p < 0.05. …”

Comparative Proteomics Analysis of Bacillus amyloliquefaciens SQR9 Revealed the Key Proteins Involved in in Situ Root Colonization by Meihua Qiu (1710367)

“…The proteins that were closely affiliated with the root colonization belonged to the functional categories of biocontrol, detoxification, biofilm formation, cell motility and chemotaxis, transport, and degradation of plant polysaccharides. A two-component system protein ResE was increased 100-fold when compared to the planktonic status; impairment of the <i>resE</i> gene postponed the formation of cell biofilm and decreased the root colonization capability, which may be regulated through the <i>spo0A</i>-<i>sinI</i>-<i>yqxM</i> pathway. …”

miR-126-3p overexpression inhibits cellular proliferation, and colony and spheroid formation. by Yin Xiong (342546)

“…<p><b>(A–C)</b> Thyroid cancer cell line proliferation with miR-126-3p overexpression. …”

La₂Co₂Se₂O₃: A Quasi-Two-Dimensional Mott Insulator with Unusual Cobalt Spin State and Possible Orbital Ordering by Cao Wang (1500691)

“…The as-prepared sample shows insulating behavior with room-temperature resistivity of ∼10⁷ Ω cm, which decreases by 4 orders of magnitude under a pressure of 7 GPa. …”

Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling by Heejin Ahn (3173670)

“…On the contrary, depletion of LDH-A or LDH-B subunit suppressed both glycolytic and mitochondrial metabolism, resulting in reduced mature osteoclast formation via decreased osteoclast precursor fusion and down-regulation of the osteoclastogenic critical transcription factor NFATc1 and its target genes. …”

5-Aza-2’-deoxycytidine in the medial prefrontal cortex regulates alcohol-related behavior and Ntf3-TrkC expression in rats by Xiaomeng Qiao (3139755)

“…Moreover, both of the mRNA and protein levels of DNA Methyltransferase 3A (DNMT3A) and DNMT3B in the mPFC were upregulated after 35 days of alcohol exposure and this upregulation could be reversed by 5-Aza-dc treatment. …”