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51621
Supplementary Information Files for Development of a hollow fibre-based renal module for active transport studies
Published 2021“…Finally, bidirectional assays have shown that cells grown in the RM were able to reabsorb albumin with a higher efciency compared to Transwell cell cultures while efux of the P-gp-specifc substrates Hoechst and Rhodamine 123 was decreased. …”
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51622
GEF-H1 mediates RhoA activation during <i>S. flexneri</i> cell invasion.
Published 2013“…Expression of GEF-H1 (Y395A) decreased baseline activation and prevented the rapid activation of RhoA during <i>Shigella</i> invasion of HEK293 cells. …”
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51623
Image_1_Schlafen family is a prognostic biomarker and corresponds with immune infiltration in gastric cancer.tif
Published 2022“…We isolated three samples of peripheral blood mononuclear cell (PBMC) and activated T cells; the results showed the expression of SLFN family members decreased significantly when T cell active. In conclusion, the SLFN family of proteins may act as a prognostic indicator of GC and is associated with immune cell infiltration and immune checkpoint expression in GC. …”
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51624
Crop residue harvest for bioenergy production and its implications on soil functioning and plant growth: A review
Published 2018“…<div><p>ABSTRACT: The use of crop residues as a bioenergy feedstock is considered a potential strategy to mitigate greenhouse gas (GHG) emissions. …”
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51625
Table_3_Corticosteroids for Treating Sepsis in Adult Patients: A Systematic Review and Meta-Analysis.doc
Published 2021“…Objective<p>Corticosteroids are a common option used in sepsis treatment. However, the efficacy and potential risk of corticosteroids in septic patients have not been well assessed. …”
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51626
Image_5_The IAG-Switch and Further Transcriptomic Insights Into Sexual Differentiation of a Protandric Shrimp.TIF
Published 2020“…<p>The insulin-like androgenic gland hormone (IAG) secreted from the androgenic gland (AG) is a unique endocrine controller (the IAG-switch) of crustacean sexual differentiation. …”
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51627
Table_1_Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.XLSX
Published 2020“…</p><p>Methods: Whole exome sequencing was performed in a 37-years-old patient with a history of diarrhea since adolescence. …”
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51628
HIV Clinical Pathway: A New Approach to Combine Guidelines and Sustainability of Anti-Retroviral Treatment in Italy
Published 2016“…From an economic point of view, the CP implementation led to a substantial advantage: the mean total costs related to the management of the HIV disease (ART, hospital admission and laboratory tests) decreased (-8.60%) in the Post-CP phase (p-value < 0.0001). …”
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51629
Pharmacological Targeting of Native CatSper Channels Reveals a Required Role in Maintenance of Sperm Hyperactivation
Published 2009“…HC-056456 does not prevent activation of motility by HCO<sub>3</sub><sup>−</sup> but does prevent the development of hyperactivated motility by capacitating incubations, thus producing a phenocopy of the CatSper-null sperm. When applied to hyperactivated sperm, HC-056456 causes a rapid, reversible loss of flagellar waveform asymmetry, similar to the loss that occurs when Ca<sup>2+</sup> entry through the CatSper channel is terminated by removal of external Ca<sup>2+</sup>. …”
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51630
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
Published 2019“…<div><p>Introduction</p><p>Right ventricular (RV) myocardial dysfunction is a common feature in septic shock. It can worsen outcome, but the etiology is poorly understood. …”
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51631
Systematic analysis of <i>CDC73</i> as a suppressor of GCRs selected in the dGCR assay.
Published 2018“…Single mutations causing decreased telomere lengths are underlined [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007170#pgen.1007170.ref046" target="_blank">46</a>,<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007170#pgen.1007170.ref047" target="_blank">47</a>]. …”
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51632
Image_2_A Potential Mechanism of Sodium Channel Mediating the General Anesthesia Induced by Propofol.tif
Published 2020“…Mathematical simulation indicated that a left shift of Na<sub>V</sub> activation produced a Hopf bifurcation, leading to cell oscillations. …”
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51633
Image_3_The IAG-Switch and Further Transcriptomic Insights Into Sexual Differentiation of a Protandric Shrimp.TIF
Published 2020“…<p>The insulin-like androgenic gland hormone (IAG) secreted from the androgenic gland (AG) is a unique endocrine controller (the IAG-switch) of crustacean sexual differentiation. …”
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51634
Video_1_Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.MOV
Published 2021“…<p>Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. …”
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51635
Video_1_Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.MOV
Published 2021“…<p>Epilepsy surgery is a common therapeutic option in humans with drug-resistant epilepsy. …”
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51636
Does dexmedetomidine have an antiarrhythmic effect on cardiac patients? A meta-analysis of randomized controlled trials
Published 2018“…Dexmedetomidine (DEX) is a popular medicine used for sedation in the ICU, and its other pharmacological characteristics are gradually being uncovered.…”
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51637
Data_Sheet_1_Hopium or empowering hope? A meta-analysis of hope and climate engagement.docx
Published 2023“…<p>Researchers are increasingly examining whether hope can motivate action on climate change, or conversely, whether it might demotivate such action. We present a meta-analysis (k = 46) of quantitative studies examining the relationships between measures and manipulations of hope with climate engagement. …”
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51638
RhoB Acts as a Tumor Suppressor That Inhibits Malignancy of Clear Cell Renal Cell Carcinoma
Published 2016“…These findings show that RhoB may play a tumor suppressive role in ccRCC cells, raising its potential value in futural therapeutic target for the patients of ccRCC.…”
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51639
Natural Form of Noncytolytic Flexible Human Fc as a Long-Acting Carrier of Agonistic Ligand, Erythropoietin
Published 2011“…<div><p>Human IgG1 Fc has been widely used as a bioconjugate, but exhibits shortcomings, such as antibody- and complement-mediated cytotoxicity as well as decreased bioactivity, when applied to agonistic proteins. …”
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51640
Data_Sheet_1_Extracutaneous features and complications of the Ehlers-Danlos syndromes: A systematic review.docx
Published 2023“…Introduction<p>The Ehlers-Danlos syndromes (EDS) comprise a group of inherited connective tissue disorders presenting with variable fragility to skin, soft tissue, and certain internal organs, which can cause significant complications, particularly arterial rupture, bowel perforation and joint difficulties. …”