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51681
Table_4_Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner.docx
Published 2019“…Microglia responded to the obesogenic conditions by a shift of substrate utilization with decreased glutamate and glucose metabolism in the active period of the animals, and an overall increase of lipid metabolism, as indicated by gene expression evaluation. …”
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51682
Image_3_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.tiff
Published 2021“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”
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51683
Table_1_Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner.docx
Published 2019“…Microglia responded to the obesogenic conditions by a shift of substrate utilization with decreased glutamate and glucose metabolism in the active period of the animals, and an overall increase of lipid metabolism, as indicated by gene expression evaluation. …”
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51684
Table1_Does sacubitril/valsartan work in children with heart failure?—a pilot study.pdf
Published 2023“…Its safety and efficacy in pediatric HF patients with cardiomyopathy or congenital heart disease are poorly understood. A pilot study was conducted to assess the clinical response, efficacy and safety of sacubitril/valsartan in this population at a tertiary care hospital in China.…”
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51685
Image_7_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.jpeg
Published 2021“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”
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51686
DataSheet_2_A Mendelian analysis of the relationships between immune cells and breast cancer.pdf
Published 2024“…</p>Results<p>According to the Bonferroni correction, no immune trait was identified with a decreased or increased risk of overall breast cancer risk. …”
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51687
IFNγ and CXCL10 has a key role in CD20-TCB T cell recruitment.
Published 2021“…<p>a-b) Top: Representative histological staining of WSU DLCL2 tumors 24h post second treatment (0.5 mg/kg CD20-TCB or suitable vehicle i.v.). …”
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51688
Table 1_Case report: Clinical and immunohistochemical manifestations of suspected Sjogren's disease in a dog.xlsx
Published 2024“…Sjogren's-like disease has been reported in a domestic shorthair cat and golden retriever dog. …”
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51689
A Pilot Trial Assessing Urinary Gene Expression Profiling with an mRNA Array for Diabetic Nephropathy
Published 2012“…Quantification of mRNA expression in urinary sediment has emerged as a novel strategy for studying renal diseases. Considering the numerous molecules involved in DN development, a high-throughput platform with parallel detection of multiple mRNAs is needed. …”
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51690
Image_5_Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis.tiff
Published 2021“…Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. …”
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51691
DataSheet1_Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor.docx
Published 2022“…<p>The autotaxin-lysophosphatidic acid (ATX-LPA) signaling pathway plays a role in a variety of autoimmune diseases, such as rheumatoid arthritis or neurodegeneration. …”
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51692
Measuring mean promoter activity and cell-to-cell variability for a library of Zap1 target promoters.
Published 2013“…<p>(<i>A</i>) The transcription factor Zap1 is induced by decreasing the concentration of zinc in the growth medium. …”
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51693
Table_2_Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner.docx
Published 2019“…Microglia responded to the obesogenic conditions by a shift of substrate utilization with decreased glutamate and glucose metabolism in the active period of the animals, and an overall increase of lipid metabolism, as indicated by gene expression evaluation. …”
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51694
Non-Alcoholic Fatty Pancreas Disease Pathogenesis: A Role for Developmental Programming and Altered Circadian Rhythms
Published 2014“…Analyses of CCG expression demonstrated a phase shift in CLOCK (−4.818, p<0.01), REV-ERB-α (−1.4,p<0.05) and Per2 (3.27,p<0.05) in association with decreased amplitude in BMAL-1 (−0.914,p<0.05) and PER2 (1.18,p<0.005) in Ob_Ob compared to Con_Con. 2-way ANOVA revealed significant interaction between MO and post-weaning OD in expression of CLOCK (p<0.005), PER1 (p<0.005) and PER2 (p<0.05) whilst MO alone influenced the observed rhythmic variance in expression of all 5 measured CCG.…”
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51695
Table_3_Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner.docx
Published 2019“…Microglia responded to the obesogenic conditions by a shift of substrate utilization with decreased glutamate and glucose metabolism in the active period of the animals, and an overall increase of lipid metabolism, as indicated by gene expression evaluation. …”
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51696
Data_Sheet_1_Prevention of Neural Tube Defects in Europe: A Public Health Failure.pdf
Published 2021“…<p>Objective: Thirty years ago it was demonstrated that folic acid taken before pregnancy and in early pregnancy reduced the risk of a neural tube defect (NTD). Despite Public Health Initiatives across Europe recommending that women take 0.4 mg folic acid before becoming pregnant and during the first trimester, the prevalence of NTD pregnancies has not materially decreased in the EU since 1998, in contrast to the dramatic fall observed in the USA. …”
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51697
Table_2_Causal effects of fatty acids on atopic dermatitis: A Mendelian randomization study.XLSX
Published 2023“…The single-SNP analyses revealed that n-3 fatty acids are likely linked to a decreased risk of AD through FADS cluster, highlighting the significance of the FADS gene in the fatty acids synthesis pathway in the development of AD.…”
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51698
Conversion from Tacrolimus to Cyclosporine A Improves Glucose Tolerance in HCV-Positive Renal Transplant Recipients
Published 2016“…</p><p>Results</p><p>After conversion, both fasting and challenged glucose levels decreased significantly. This was mainly attributable to a significant amelioration of post-prandial dynamic glucose sensitivity as measured by the oral glucose sensitivity-index OGIS [422.17 (370.82–441.92) vs. 468.80 (414.27–488.57) mL/min/m2, p = 0.005), which also resulted in significant improvements of the disposition index (p = 0.017) and adaptation index (p = 0.017) as markers of overall glucose tolerance and beta-cell function. …”
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51699
Development of a multivariable prediction model for identification of patients at risk for medication transfer errors at ICU discharge
Published 2019“…<div><p>Introduction</p><p>Discharge from the intensive care unit (ICU) is a high-risk process, leading to numerous potentially harmful medication transfer errors (PH-MTE). …”
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51700
Reappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes: A Meta-Analysis of Randomised Controlled Trials
Published 2012“…We cannot exclude a 33% reduction or a 64% increase in cardiovascular mortality. …”