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51741
Table_3_Targeting metabolic pathways: a novel therapeutic direction for type 2 diabetes.docx
Published 2023“…</p>Results<p>Our findings revealed a reduction in both the species diversity and abundance of intestinal flora in T2DM mice, with significantly decreased levels of beneficial bacteria such as Lactobacillus and significantly increased levels of harmful bacteria such as Helicobacter pylori. …”
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51742
Image_8_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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51743
Amino Acid Substitutions of MagA in <em>Klebsiella pneumoniae</em> Affect the Biosynthesis of the Capsular Polysaccharide
Published 2012“…The G334A mutant remained mucoid with decreased CPS production, but its virulence was significantly reduced <em>in vivo</em>. …”
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51744
Denitrifying Bacterial Communities Affect Current Production and Nitrous Oxide Accumulation in a Microbial Fuel Cell
Published 2013“…Current production decreased from 15.0 A·m<sup>−3</sup> NCC (Net Cathodic Compartment), when nitrate was used as an electron acceptor, to 14.1 A·m<sup>−3</sup> NCC in the case of nitrite. …”
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51745
<i>CCHa2</i> is a selective nutrient-sensitive hormone derived from peripheral tissues.
Published 2015“…<p>(A) RT-qPCR was performed on RNA extracted from larval tissues. …”
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51746
Table 1_Sex disparities in the risk of intracranial aneurysm rupture: a case–control study.docx
Published 2024“…Compared with males, females had a higher risk of ruptured IA [odds ratio, 1.72 (95% confidence interval, 1.38–2.14)]. …”
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51747
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury
Published 2024“…Mitogen-activated protein kinase-interacting protein kinases (MNKs) and phosphorylate eukaryotic initiation factor 4E (p-eIF4E) play a critical role in regulating mRNA translation and protein synthesis associated with the development of cancer, metabolism, and inflammation. …”
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51748
Image_1_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF
Published 2024“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”
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51749
Data_Sheet_2_The mirror mechanism in schizophrenia: A systematic review and qualitative meta-analysis.pdf
Published 2022“…Previous studies report its malfunction in autism, opening doors to investigate the underlying pathophysiology of the disorder in a more elaborate way and coming up with new rehabilitation methods. …”
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51750
Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics
Published 2019“…Moreover, immunoprecipitation assays verified a direct interaction between USP9X and NFX1-123. …”
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51751
Data_Sheet_2_Autonomic Nervous System Function in Anorexia Nervosa: A Systematic Review.docx
Published 2021“…The current review aimed to synthesize the evidence of basal ANS function in individuals with a current diagnosis of AN and those with a previous diagnosis who had achieved weight restoration, as compared to controls.…”
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51752
Chirality Transfer of Stereogenic Boron Centers Enabled by a S<sub>N</sub>2‑Type Mechanism
Published 2024“…For other cases, decreased or inverse enantioselectivity was rationalized by a solvent-assisted pathway.…”
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51753
Dendritic spine density is reduced exclusively at dystrophic, soluble Aβ and hyperphosphorylated tau accumulating dendrites.
Published 2010“…<p>(A, B) Time-lapse images of dystrophic and non-dystrophic dendrites over 60 days. …”
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51754
Image_2_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.TIFF
Published 2019“…<p>Postoperative delirium is a frequent and debilitating complication, especially amongst high risk procedures such as orthopedic surgery, and its pathogenesis remains unclear. …”
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51755
Simulation-based validation of spatial capture-recapture models: A case study using mountain lions
Published 2019“…Model results were sensitive to the quantity of available information: density estimates based on low search effort were biased high and imprecise, whereas estimates based on high search effort were unbiased and precise. A correlation between search effort and animal density resulted in a positive bias in density estimates, though the bias decreased with increasingly informative datasets. …”
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51756
Fitness landscape under a random genetic code ensemble incorporating the amino acid frequency in the genomes.
Published 2023“…Principal component analysis and k-means clustering were performed using the sampled data with a cost value of <i>cost</i> < 2.9 + Δ. (B) Fitness landscape visualized by piling up the scatterplot on the PC1-PC2 plane, with costs decreasing on the vertical axis (left panel). …”
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51757
Ca<sup>2+</sup> signalling and mitochondrial physiology defects in cells lacking anxA6.
Published 2013“…In response to oligomycin, ΔΨm increased in <i>AnxA6</i><sup>+/+</sup> cells but decreases in the <i>AnxA6</i><sup>−/−</sup> cells, suggesting that ΔΨm is maintained by a reversal of the F1-FoATPsynthase. …”
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51758
Cognitive Bias Modification versus CBT in Reducing Adolescent Social Anxiety: A Randomized Controlled Trial
Published 2013“…<div><p></p><p>Social anxiety is a common mental disorder among adolescents and is associated with detrimental long term outcomes. …”
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51759
The relationship between bile acids levels and the prognosis of patients with diabetes on maintenance hemodialysis: a retrospective study
Published 2023“…The multivariate Cox regression analysis demonstrated that patients with DM on MHD with higher BAs were associated independently with a decreased risk of all-cause death (HR =0.55; 95% CI, 0.35–0.81, <i>p</i> = 0.01) compared to those with lower BAs levels.…”
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51760
Alterations in gut microbiota and plasma metabolites in patients with generalized anxiety disorder: a multi-omics study
Published 2025“…Notably, microbiome–metabolome combined analysis revealed a significant correlation between intestinal flora disorders and changes in the plasma metabolic profile. …”