Image_3_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.TIF by Zhen Tang (2977569)

“…Therefore, our results explain one underlying mechanism of increasing the sensitivity of osteosarcoma to chemotherapy and suggest that Sestrin2 is a promising gene target.</p>…”

Data Sheet 5_Novel idebenone derivatives attenuated oxidative stress injury and myocardial damage.zip by Yuwei Peng (17203933)

“…Our results demonstrated that IDE derivatives could be a new research direction for the treatment of cardiovascular diseases associated with oxidative stress.…”

Data Sheet 1_Abundance, occurrence, and degradation of airborne antibiotic resistance genes in coastal and marine atmospheres.docx by Shijie Jia (5749301)

“…Here, we report observations of ambient ARGs during a cruise over the marginal seas of the Bohai Sea and Yellow Sea and compare them with ARGs in the coastal atmosphere. …”

TolB is crucial for <i>P. aeruginosa</i> resistance and persistence. by Alessandra Lo Sciuto (610616)

“…<p>(A) Growth of PAO1 (circles) and PAO1 <i>tolB</i> conditional mutant (diamonds) at 37°C in MH broth at 200 rpm in flasks after two successive subcultures in the presence (filled symbols) or in the absence (open symbols) of 0.2% arabinose. …”

Image_1_Bidirectional modulation of synaptic transmission by insulin-like growth factor-I.tif by José Antonio Noriega-Prieto (18781546)

“…<p>Insulin-like growth factor-I (IGF-I) plays a key role in the modulation of synaptic plasticity and is an essential factor in learning and memory processes. …”

Table_1_MicroRNA 3′ ends shorten during adolescent brain maturation.XLSX by Kristen T. Thomas (15288109)

“…We conclude that age-associated miRNA 3′ shortening is a well-conserved feature of postnatal brain maturation.…”

image1_Soluble Epoxide Hydrolase Inhibition Prevents Experimental Type 4 Cardiorenal Syndrome.tiff by Mouad Hamzaoui (10287428)

“…Thus, inhibition of sEH holds a therapeutic potential in preventing type 4 cardiorenal syndrome.…”

Kaplan-Meier Survival Curves Comparing Patient Marital Status among patients who did not undergo cancer-directed surgery. by Michael Baine (349875)

“…<p>A Kaplan-Meier survival curve comparing survival based on marital status among all patients diagnosed with pancreatic ductal adenocarcinoma (PC) between 1998 and 2003 with known marital status who <i>did not undergo</i> cancer-directed surgery. …”

Video_1_Clinical advantages and neuroprotective effects of monitor guided fang’s capillary fascia preservation right RLN dissection technique.mp4 by Qian Shi (28174)

“…</p>Conclusions<p>F-R-RLN dissection is a thorough dissection technique that is effective at preventing an electrical signal amplitude decrease in the RLN, and at preventing RLN paralysis by preserving its blood supply.…”

Data - Climate change impacts on Lactuca sativa.xlsx by Nicholas Yos (21507818)

“…Climate change-induced shifts in these environmental conditions have the potential to significantly affect nearly all terrestrial plants. A number of studies have explored the impacts of changing one or two of the conditions listed above, but few have examined the combined effects of all three. …”

DataSheet1_Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem—implications for channelopathies.pdf by Salma Allam (16836396)

“…Interestingly, fast-inactivating channels, including Familial Hemiplegic Migraine mutants, are more potently inhibited than WT channels, while slow-inactivating channels, such as those expressed with the Cavβ_2a auxiliary subunit, are spared. We found similar results in L-type channels, and, remarkably, Timothy Syndrome mutant channels were insensitive to Gem inhibition. …”

Image_3_Microbial communities are thermally more sensitive in warm-climate lizards compared with their cold-climate counterparts.TIF by Xia-Ming Zhu (8601639)

“…To elucidate the role of gut microbiota in thermal adaptation, we designed a 2 species × 3 temperatures experiment, whereby we acclimated adult males of two agamid lizard species (warm-climate Leiolepis reevesii and cold-climate Phrynocephalus przewalskii) to 20, 28, and 36°C for 2 weeks and then collected their fecal and small-intestinal samples to analyze and compare the microbiota using 16S rRNA gene amplicon sequencing technology. …”

DataSheet1_Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.ZIP by Zimengwei Ye (13757419)

“…These effects may be linked to the stimulation of GLUT4 expression and translocation via regulating AMPKα/SIRT1/PGC-1α signaling pathway. The results may offer a novel explanation of JTSHF to prevent against diabetes and IR-related metabolic diseases.…”

Whole-brain Functional Networks in Cognitively Normal, Mild Cognitive Impairment, and Alzheimer’s Disease by Eun Hyun Seo (106201)

“…In contrast, individual parameters of the network were altered with the following patterns of changes: local clustering of networks was lower in both MCI and AD compared to CN, while path length was not different among the three groups. Then, MCI had a lower level of local clustering than AD. Subgroup analyses for AD also revealed that very mild AD had lower local clustering and shorter path length compared to mild AD. …”

Data_Sheet_1_Communication Mechanism and Optimization Strategies of Short Fitness-Based Videos on TikTok During COVID-19 Epidemic Period in China.PDF by Jinlong Shi (495868)

“…Through the communication channels mainly composed of texts, pictures, and audio, the communication subjects carry out multilevel interactive communication with the communication objects; (2) fitness preferences are mainly composed of dances, unarmed fitness, and fitness with equipment; (3) from the perspective of time, taking February 20 as the node, the daily number of released short videos shows a trend of “increase before decrease”; from the perspective of space, the distribution is significantly unbalanced across provinces, and the direction is not apparent; and (4) this article explores the communication mechanism and targeted optimization countermeasures of short fitness-based videos on TikTok in China's COVID-19 epidemic period.…”

Table_2_Antidiabetic effect of sciadonic acid on type 2 diabetic mice through activating the PI3K-AKT signaling pathway and altering intestinal flora.DOCX by Lin Chen (54305)

“…<p>Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by hyperglycemia. …”

<i>Drosophila</i> Mitf regulates the V-ATPase and the lysosomal-autophagic pathway by Valentina Bouché (842830)

“…Furthermore, we show Mitf-mediated clearance of cytosolic and nuclear expanded ATXN1 (ataxin 1) in a cellular model of spinocerebellar ataxia type 1 (SCA1). …”

Table_1_Roles of Gastric Emptying and Gastrointestinal Transit Following Ileal Interposition in Alleviating Diabetes in Goto-Kakizaki Rats.docx by Yanmin Wang (660089)

“…</p>Conclusions<p>Although IT inhibits the GI transit time, the earlier interaction between undigested nutrients and interpositioned ileum promotes gut hormone secretion and thus reduces body weight and alleviates hyperglycemia. A decrease of GI transit of IT rats exacerbates the antidiabetic effects.…”

Data_Sheet_1_Populus SVL Acts in Leaves to Modulate the Timing of Growth Cessation and Bud Set.PDF by Domenique André (12098645)

“…<p>SHORT VEGETATIVE PHASE (SVP) is an important regulator of FLOWERING LOCUS T (FT) in the thermosensory pathway of Arabidopsis. It is a negative regulator of flowering and represses FT transcription. …”

Table_1_The Aging Features of Thyrotoxicosis Mice: Malnutrition, Immunosenescence and Lipotoxicity.xlsx by Qin Feng (147009)

“…The results of routine blood tests and flow cytometry showed that immunosenescence occurred in thyrotoxicosis mice, which was characterized by a significant decrease in neutrophils, lymphocytes, CD4+/CD8+ and CD4+IFN-γ+ lymphocytes. …”