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145781
TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth
Published 2016“…<p>We previously reported that aberrant TGF-β/Smad2/3 signaling in endometrial cancer (ECA) leads to continuous ubiquitylation of p27<sup>kip1</sup>(p27) by the E3 ligase SCF-Skp2/Cks1 causing its degradation, as a putative mechanism involved in the pathogenesis of this cancer. …”
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145782
Presentation_1_Pregnancy Gestation Impacts on HIV-1-Specific Granzyme B Response and Central Memory CD4 T Cells.pdf
Published 2020“…Longitudinal analysis of pregnant participants demonstrated transient increases in Gag granzyme B response and in the central memory CD4 T-cell subset frequency during their second trimester, with a decrease in CD4 effector memory T cells from their second to third trimester. …”
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145783
Image_6_Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice.tif
Published 2022“…<p>Temporal lobe epilepsy, a chronic disease of the brain characterized by degeneration of the hippocampus, has impaired risk assessment. …”
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145784
Data_Sheet_1_Stochastic partial budget analysis of strategies to reduce the prevalence of lung lesions in finishing pigs at slaughter.PDF
Published 2022“…A partial budget analysis was then performed in which the baseline farm was compared with two hypothetical strategies aimed at reducing the occurrence and spread of respiratory diseases during pig production: (S1) avoiding mixing of litters after weaning and (S2) keeping purchased pregnant gilts separated from sows during gestation, farrowing and lactation. …”
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145785
Table_2_The Micro-RNA Cargo of Extracellular Vesicles Released by Human Adipose Tissue-Derived Mesenchymal Stem Cells Is Modified by Obesity.xlsx
Published 2021“…<p>Obesity is a chronic disease that interferes with normal repair processes, including adipose mesenchymal stem/stromal cells (ASCs) function. …”
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145786
Data_Sheet_4_Low Oxygen Levels Induce Early Luteinization Associated Changes in Bovine Granulosa Cells.xlsx
Published 2018“…<p>During follicle maturation, oxygen levels continuously decrease in the follicular fluid and reach lowest levels in the preovulatory follicle. …”
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145787
Table_1_The spatial and temporal distribution of China’s forest carbon.DOCX
Published 2023“…Introduction<p>China’s forests have sequestrated a significant amount of carbon over the past two decades. …”
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145788
Image_2_Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice.tif
Published 2022“…<p>Temporal lobe epilepsy, a chronic disease of the brain characterized by degeneration of the hippocampus, has impaired risk assessment. …”
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145789
Asymptomatic fluid overload predicts survival and cardiovascular event in incident Chinese peritoneal dialysis patients
Published 2018“…</p><p>Methods</p><p>We performed a single-center study on 311 incident PD patients. …”
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145790
Table15_BuShen HuoXue decoction improves fertility through intestinal hsp-16.2-mediated heat-shock signaling pathway in Caenorhabditis elegans.DOCX
Published 2023“…</p><p>Methods: Bisphenol A (BPA, 175 μg/mL) was used to establish a fertility-defective C. elegans model. …”
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145791
Data Sheet 1_Global burden of chronic kidney disease due to hypertension attributable to dietary risks in adults aged 25 years and older: findings from the global burden of disease...
Published 2025“…Background<p>Suboptimal diet remains a major threat to chronic kidney diseases (CKD) and hypertension, however, the burden of diet-attributable CKD due to hypertension (HCKD) has been poorly quantified and reported. …”
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145792
Data_Sheet_1_Epidemiological Characteristics of Infectious Diseases Among Travelers Between China and Foreign Countries Before and During the Early Stage of the COVID-19 Pandemic.Z...
Published 2021“…<p>Background: International travel during the Coronavirus disease 2019 (COVID-19) pandemic carries a certain magnitude of infection risk both to travelers and their destination, which may be difficult to assess in the early stage. …”
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145793
Data_Sheet_1_Response Mechanism of Endogenous Hormones of Potential Storage Root to Phosphorus and Its Relationship With Yield and Appearance Quality of Sweetpotato.ZIP
Published 2022“…Moreover, a significant decrease in the expression of AAO and concentration of ABA was observed from 10 to 30 days after planting, and a significant increase was observed after 40 days of planting. …”
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145794
Data Sheet 1_Unraveling microbial shifts and plant growth responses in Chrysanthemum ‘Merlino’ due to artificial root exudates in horticultural substrates.pdf
Published 2025“…The relative abundance of certain fungi increased in treatments with artificial root exudates, particularly those capable of metabolizing hexose or pentose sugars. That lead to a decrease in overall fungal diversity. Although bacterial diversity was not affected, the addition of artificial root exudates enhanced their metabolic diversity. …”
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145795
Early <i>BCR-ABL1</i> Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia
Published 2017“…In conclusion, early treatment response analysis defines a biologically distinct patient subgroup with inferior long-term outcomes.…”
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145796
Table_2_Long-Term Outcome After Out-of-Hospital Cardiac Arrest: An Utstein-Based Analysis.DOCX
Published 2021“…Pre-hospital data, survival, and cerebral performance category score (CPC) at 1, 6, and 12 months and then every year up to 5 years after the event were analyzed for each patient.</p><p>Results: A decrease in survival was observed during the follow-up in all the Utstein categories. …”
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145797
Supplementary Material for: Close Relations between Podocyte Injuries and Membranous Proliferative Glomerulonephritis in Autoimmune Murine Models
Published 2013“…Furthermore, both MPGN models showed a decrease in immune-positive areas of nephrin, podocin and synaptopodin in the glomerulus, and in the mRNA expression of <i>Nphs1</i>, <i>Nphs2</i>, <i>Synpo</i>, <i>Actn4</i>, <i>Cd2ap</i>, and <i>Podxl </i>in the isolated glomerulus. …”
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145798
Image 3_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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145799
Table 2_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci...
Published 2025“…Nevertheless, there was an impact (p < 0.05) from training status (but not HMB/PLA) on FM (kg; slight increases in UTR) and TBW (slight decreases in UTR).</p>Discussion<p>The individually adjusted high HMB dose did not change body mass and composition in trained or untrained individuals during a three-week exclusive supplementation or three-week supplementation in combination with additional HIFT stimuli. …”
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145800
Supplementary Material for: Microarray Profiling of TGF-β1-Induced Long Non-Coding RNA Expression Patterns in Human Lung Bronchial Epithelial BEAS-2B Cells
Published 2018“…<b><i>Methods:</i></b> To reveal new molecules of regulatory functions in this process, lncRNA microarray was performed to profile both lncRNA and mRNA expression patterns in human lung bronchial epithelial BEAS-2B cells treated with TGF-β1 at a concentration measured in the medium conditioned by directly irradiated BEAS-2B cells. …”