Blocking the A_2B adenosine receptor alleviates myocardial damage by inhibiting spleen-derived MDSC mobilisation after acute myocardial infarction by Zongying Yu (10052796)

“…In AMI model mice, the percentage of MDSCs was increased in the circulation and infarcted heart and decreased in the spleen. MRS-1754-mediated A_2BAR inhibition decreased the MDSC ratio in the circulation and infarcted heart and prevented the decrease in MDSC number in the spleens of mice with AMI. …”

Comparing the 5-year risk of CVD under no intervention (observed risk) and simulated (g-form risk) for A) HbA1C-SD and B) FPG-SD model. by Khadije Maajani (10125692)

Primary data from SGA screens with <i>yhp1-13A yox1-9A</i> and <i>yhp1Δ yox1Δ</i>. by Michelle M. Conti (13514386)

Linear Metal−Metal-Bonded Tetranuclear M−Mo−Mo−M Complexes (M = Ir and Rh):  Oxidative Metal−Metal Bond Formation in a Tetrametallic System and 1,4-Addition Reaction of Alkyl Halid... by Masato Ohashi (1328496)

“…Reaction of Mo₂(pyphos)₄ (<b>1</b>) with [MCl(CO)₂]₂ (M = Ir and Rh) afforded linear tetranuclear complexes of a formula Mo₂M₂(CO)₂(Cl)₂(pyphos)₄ (<b>2</b>, M = Ir; <b>3</b>, M = Rh). …”

Functional analysis of a <i>kh</i>^<i>w</i> mutant mosquitoes. by Si Yu Zhao (19544793)

Percentual change in retinal thicknesses as a function of age for the 3 mm radius circular macular region. by David Romero-Bascones (14265633)

Functional Sites Induce Long-Range Evolutionary Constraints in Enzymes by Benjamin R. Jack (2637040)

“…Here, we report pervasive conservation gradients toward catalytic residues in a dataset of 524 distinct enzymes: evolutionary conservation decreases approximately linearly with increasing distance to the nearest catalytic residue in the protein structure. …”

LiCl administered via 0.5% LiCl food pellets for 8 wks decreases GFAP levels in surviving <i>Gfap</i>-R236H/+ mice. by Christine M. LaPash Daniels (796881)

“…<p>(A) 81.8% (9/11) +/+ mice and 54.5% (6/11) R236H/+ mice survived 8 wks of LiCl treatment. …”

LiCl administered via 0.5% LiCl food pellets for 4 wks decreases GFAP levels in <i>Gfap</i>-R236H/+ mice. by Christine M. LaPash Daniels (796881)

“…<p>(A) Survival analysis for mice treated with 0.5% LiCl in food pellets for 4 wks. 94.7% (36/38) R236H/+ mice survived LiCl treatment while 100% of mice in other groups survived. …”

Induction of RoxS leads to decreased <i>ppnKB</i> mRNA levels. Northern blot showing decreased <i>ppnKB</i> mRNA levels upon RoxS induction. by Sylvain Durand (67030)

Discovery of a Novel Class of d‑Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform by Haifeng Tang (488592)

“…d-Serine is a coagonist of the <i>N</i>-methyl d-aspartate (NMDA) receptor, a key excitatory neurotransmitter receptor. …”

13C-NMR fitting of M0 (a), M1 (b), M2 (c). by Shufeng Zhao (12820875)

vFLIP maintains intestinal barrier integrity in a short term model <i>in vivo</i>. by Barbara Ruder (8379354)

Discovery of a Novel Class of d‑Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform by Haifeng Tang (488592)

“…d-Serine is a coagonist of the <i>N</i>-methyl d-aspartate (NMDA) receptor, a key excitatory neurotransmitter receptor. …”

Composition (%) and gross chemical content (g/kg as fed) of the piglets experimental diets^a. by M. Girard (8501361)

Estimating Missing Unit Process Data in Life Cycle Assessment Using a Similarity-Based Approach by Ping Hou (17213)

“…., meter readings, operation logs/journals) is often costly and time-consuming. We propose a new computational approach to estimate missing unit process data solely relying on limited known data based on a similarity-based link prediction method. …”

Oral L-Arg and D-Arg increased arginase protein expression in the liver, but L-Arg decreased it in the upper small intestine (Sm. Intes.), whereas L-Arg decreased arginase activity... by Dain (Raina) Kim (16726470)

Meta-analysis for ever smoking and risk of A) all-cause dementia, B) Alzheimer’s disease and C) vascular dementia. by Guochao Zhong (701289)

Smoking Is Associated with an Increased Risk of Dementia: A Meta-Analysis of Prospective Cohort Studies with Investigation of Potential Effect Modifiers by Guochao Zhong (701289)

“…<div><p>Background</p><p>Previous studies showed inconsistent results on the association of smoking with all-cause dementia and vascular dementia (VaD), and are limited by inclusion of a small number of studies and unexplained heterogeneity. …”

Meta-analysis for former smoking and risk of A) all-cause dementia, B) Alzheimer’s disease and C) vascular dementia. by Guochao Zhong (701289)