A Novel Form of Progressive Retinal Atrophy in Swedish Vallhund Dogs by Ann E. Cooper (627197)

“…The screening of the pure-bred dog population for new forms of PRA represents an important strategy to establish new large animal models. By examining 324 dogs of the Swedish vallhund breed in seven countries and across three continents, we were able to describe a new and unique form of PRA characterized by the multifocal appearance of red and brown discoloration of the tapetal fundus followed over time by thinning of the retina. …”

Effectiveness of theophylline administration in neonates with perinatal asphyxia: a meta-analysis by Ioannis Bellos (5432687)

“…</p> <p>The present findings suggest the effectiveness of theophylline in ameliorating renal function of asphyxiated neonates. Future large-scale trials should assess potential long-term adverse outcomes in clinical practice.Keynotes</p><p>Asphyxia is a major cause of acute kidney injury in neonates</p><p>Acute kidney injury is associated with adverse clinical outcomes in asphyxiated neonates.…”

G-code machines used for the growth of a P23 cell. by Frederic Zubler (446114)

“…During elongation the direction is chosen along the gradient of the layer specific signaling cue. The diameter decreases during elongation and at bifurcation, and is constantly assessed (with the primitive ‘morph’): as long as the diameter is large enough branching occurs further; when the diameter falls under a threshold, the growth cone removes itself and the elongation stops.…”

Treatment with vitamin D3 reduced the viability of cancer cell lines: <i>1A & 1B.</i> by Vidya G. Bettada (22208808)

“…Mouse EAC cells showed a decrease in cell viability starting from 250 µM at 24h of treatment. …”

Treatment of C6 cells with vitamin D3 reduced the number of cells in a time and dose dependent fashion. by Vidya G. Bettada (22208808)

The expression level of adipogenic gene. by Yunjun Liao (728631)

Pharmacokinetic interaction between peimine and paeoniflorin in rats and its potential mechanism by Qiangjun Chen (10306616)

“…Moreover, the transportation of paeoniflorin was also inhibited by peimine as the efflux ratio decreased from 3.06 to 1.63.</p> <p>Peimine increased the systemic exposure of paeoniflorin through inhibiting the activity of CYP3A4 and P-gp. …”

miR-204-5p is downregulated in glioma tissues. by Zhiqiang Xia (764303)

“…<p>A, Decreased levels of miR-204-5p were positively correlated with the status of pathology classification by qRT–PCR). **, <i>p</i>< 0.01 compared with the control group. …”

Data_Sheet_1_Case Report: Exome Sequencing Identified a Novel Frameshift Mutation of α-Actin 1 in a Chinese Family With Macrothrombocytopenia and Mild Bleeding.DOCX by Fang-Mei Luo (10990548)

“…<p>Inherited macrothrombocytopenia (IMTP) is a rare disorder characterized by a reduced platelet count and abnormally large platelets. …”

Data_Sheet_1_Long-Term Trends and Impact of SARS-CoV-2 COVID-19 Lockdown on the Primary Productivity of the North Indian Ocean.docx by N. Sunanda (11354325)

“…The interannual variability of NPP reveals a decreasing trend in NPP, which is interlinked with the increasing trend in SST and AOD. …”

Resource availability alters breeding strategies in a small mammal community by Ryan Stephens (10929405)

“…<p>Following a resource pulse, animals may finance reproduction by consuming concurrently available resources (income breeding) or by storing resources for future reproduction (capital breeding). …”

Notional schemes and diagrams for catalysis by K13A PTEN, wild-type PTEN, and PTEN-L. by Sean B. Johnston (685153)

“…Increasing salt concentration leads to decreasing affinity for PIP₂ and a greater fraction of the enzyme being in the T state. …”

Knocking out COL5A1 from smooth muscle does not impact chronic hypoxia-induced pulmonary hypertension by Laura Gonzalez bosc (758309)

“…We found no significant differences in PH indexes</p> <p>between the control and SMC-col5a1 KO mice, while col V seems to be decreased in pulmonary arteries</p> <p>validating the mouse model. …”

miR-204-5p inhibits glioma cell growth <i>in vitro</i>. by Zhiqiang Xia (764303)

“…<p>A, More than 200-fold increase in the expression of miR-204-5p was observed in Lv-miR-204-5p-LN229 cells and Lv-miR-204-5p-U87 cells compared to the LEV group by qRT-PCR. …”

Table_1_LMNA mutation leads to cardiac sodium channel dysfunction in the Emery-Dreifuss muscular dystrophy patient.docx by Kseniya Perepelina (13138890)

“…Induced pluripotent stem cell-derived cardiomyocytes with LMNA p.R249Q genetic variant showed a decreased sodium current density and an impaired sodium current kinetics alongside with changes in transcription levels of cardiac-specific genes. …”

Data_Sheet_1_Algometer Assessment of Pressure Pain Threshold After Onabotulinumtoxin-A and Physical Therapy Treatments in Patients With Chronic Migraine: An Observational Study.DOC... by Manuela Deodato (11135016)

“…As regards headache parameters, frequency and duration of the attacks were decreased significantly in all three treatment groups, whereas in pain intensity, the reduction was statistically significant in the combined treatment group and the onabotulinumtoxin-A therapy. …”

Table_1_Algometer Assessment of Pressure Pain Threshold After Onabotulinumtoxin-A and Physical Therapy Treatments in Patients With Chronic Migraine: An Observational Study.docx by Manuela Deodato (11135016)

“…As regards headache parameters, frequency and duration of the attacks were decreased significantly in all three treatment groups, whereas in pain intensity, the reduction was statistically significant in the combined treatment group and the onabotulinumtoxin-A therapy. …”

Data_Sheet_2_Algometer Assessment of Pressure Pain Threshold After Onabotulinumtoxin-A and Physical Therapy Treatments in Patients With Chronic Migraine: An Observational Study.ZIP by Manuela Deodato (11135016)

“…As regards headache parameters, frequency and duration of the attacks were decreased significantly in all three treatment groups, whereas in pain intensity, the reduction was statistically significant in the combined treatment group and the onabotulinumtoxin-A therapy. …”

Modeling of intercellular coupling mechanisms in a population of simulated SCN cells. by Caroline H. Ko (240081)

“…In the limit of a large number of molecules, the results of the stochastic simulations (blue) agreed with the deterministic simulations (red) when the same parameter values were used. …”

Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway by Stéphanie Duhamel (2699008)

“…Reduction of Aurora A levels by RNA interference or pharmacological inhibition of MEK1/2 reverts the defect in cytokinesis and decreases the frequency of abnormal cell divisions induced by oncogenic H-Ras^V12. …”