Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

“…<p>Endometrial cancer (EC) is a common and deadly cancer in women and novel therapeutic approaches are urgently needed. …”

SCD1 methylation in subcutaneous adipose tissue associated with menopausal age by S. Lu (728771)

“…In the rat study, the mRNA levels of SCD1 decreased (<i>P</i> < 0.001) and those of DNMT3A (<i>P</i> < 0.001) and DNMT3B increased (<i>P</i> < 0.001) after ERT.…”

Table_2_Dynamic Expression of m6A Regulators During Multiple Human Tissue Development and Cancers.XLSX by Ya Zhang (7980)

“…We found that m⁶A regulators globally exhibited decreased expression during development. …”

DataSheet1_Two-decade variability and trend of chlorophyll-a in the Arabian Sea and Persian Gulf based on reconstructed satellite data.docx by Mengmeng Yang (475288)

“…Rising SST anomalies (SST_A) correlated with reduced Chl-a anomalies (Chl-a_A) in the western AS, while increased wind anomalies (Wind_A) enhanced Chl-a_A in the western AS but decreased it in the southern PG. …”

Table_1_miR-26a Reverses Multidrug Resistance in Osteosarcoma by Targeting MCL1.XLSX by Ming Li (91180)

“…Mechanistically, miR-26a directly targets the pro-survival protein myeloid cell leukemia 1 (MCL1), and in turn, the enforced expression of MCL1 markedly antagonizes miR-26a-decreased MDR in osteosarcoma MDR cells, therefore demonstrating that miR-26a reverses MDR in osteosarcoma by targeting MCL1. …”

Table_1_Dynamic Expression of m6A Regulators During Multiple Human Tissue Development and Cancers.XLSX by Ya Zhang (7980)

“…We found that m⁶A regulators globally exhibited decreased expression during development. …”

Image_1_miR-26a Reverses Multidrug Resistance in Osteosarcoma by Targeting MCL1.TIF by Ming Li (91180)

“…Mechanistically, miR-26a directly targets the pro-survival protein myeloid cell leukemia 1 (MCL1), and in turn, the enforced expression of MCL1 markedly antagonizes miR-26a-decreased MDR in osteosarcoma MDR cells, therefore demonstrating that miR-26a reverses MDR in osteosarcoma by targeting MCL1. …”

Data_Sheet_1_Dynamic Expression of m6A Regulators During Multiple Human Tissue Development and Cancers.PDF by Ya Zhang (7980)

“…We found that m⁶A regulators globally exhibited decreased expression during development. …”

Induction of Noxa contributes to ISG12a-mediated apoptosis. by Darong Yang (340067)

“…(<b>C</b>) Silencing of ISG12a or overexpression of miR-942 decreased Noxa expression. …”

Image_2_miR-26a Reverses Multidrug Resistance in Osteosarcoma by Targeting MCL1.TIF by Ming Li (91180)

“…Mechanistically, miR-26a directly targets the pro-survival protein myeloid cell leukemia 1 (MCL1), and in turn, the enforced expression of MCL1 markedly antagonizes miR-26a-decreased MDR in osteosarcoma MDR cells, therefore demonstrating that miR-26a reverses MDR in osteosarcoma by targeting MCL1. …”

Particle size distribution curve (a) and XRD pattern (b) of standard siliceous sand. Particle size distribution of the standard siliceous sand was measured using a laser particle s... by Liang Xiong (1426411)

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

<i>Odorant binding protein 69a</i> connects social interaction to modulation of social responsiveness in <i>Drosophila</i> by Assa Bentzur (5076254)

“…Its expression is inversely regulated in male and female flies by social interactions: cVA exposure reduces its levels in male flies and increases its levels in female flies. Increasing or decreasing Obp69a levels by genetic means establishes a functional link between Obp69a levels and the extent of male aggression and female receptivity. …”

Stereotactic Aspiration versus Craniotomy for Primary Intracerebral Hemorrhage: A Meta-Analysis of Randomized Controlled Trials by Jia-Wei Wang (229070)

“…<div><p>Background</p><p>A wealth of evidence based on the randomized controlled trials (RCTs) has indicated that surgery may be a better choice in the management of primary intracerebral hemorrhage (ICH) compared to conservative treatment. …”

Perineural Dexmedetomidine as an Adjuvant Reduces the Median Effective Concentration of Lidocaine for Obturator Nerve Blocking: A Double-Blinded Randomized Controlled Trial by Yuechun Lu (3163686)

“…term=NCT02066727&rank=1" target="_blank">NCT02066727</a></p></div>…”

Table_1_Slc7a14 Is Indispensable in Zebrafish Retinas.pdf by You-Yuan Zhuang (8116280)

“…The immunostaining results revealed that the rod-specific protein zpr-3 and the retinal pigment epithelium-specific protein zpr-2 (decreased to 44.48%) were significantly suppressed in the slc7a14-silenced morphants. …”

Economic review of point-of-care EEG by Adam Green (14072544)

“…</p> <p><b>Limitations:</b> We conducted a narrative review, not a systematic review. The studies were observational and utilized one rapid circumferential headband system, which limited generalizability of the findings and indicated publication bias. …”

Shifts in Abundance and Diversity of Soil Ammonia-Oxidizing Bacteria and Archaea Associated with Land Restoration in a Semi-Arid Ecosystem by Zhu Chen (3106)

“…Nv6 which had possibly adapted to high concentrations of inorganic nitrogen, decreased on the restored land. Only a slight difference in the AOB communities was observed between the restored land with and without the shrub (<i>Caragana korshinskii</i> Kom.). …”