IOP and Medication Plots. by Hardik A. Parikh (2136592)

Correlation analysis of miR-27a/b-3p levels with disease severity and duration. by Soudabeh Fazeli (9623952)

“…<p><b>(A)</b> PBMCs derived miR-27a-3p level decreased along with the disease severity. …”

Inhibiting Gamma-secretase activity without interfering in Notch signaling: Decreasing the inflammatory response in patients with cutaneous leishmaniasis by Lucas Carvalho (3093042)

“…</b>Monocytes from HS (n= 5) were infected with <i>L. braziliensis</i>in stationary phase (ratio 5:1) and cultured in presence or absence of JLK6 (20µM) for 2, 48 and 72 hours. (A) Frequency of infected cells. (B) Number of <i>Leishmania </i>amastigotes/100 monocytes. …”

The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility by Magdalena H. Menhofer (659026)

“…On the signaling level, RhoA activity is decreased by Chondramide accompanied by reduced MLC-2 and the stretch induced guanine nucleotide exchange factor Vav2 activation. …”

Image_2_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

Table_1_Cardiotonic Pills Plus Recombinant Human Prourokinase Ameliorates Atherosclerotic Lesions in LDLR–/– Mice.DOCX by Jing-Na Deng (7363091)

“…No effect was observed for proUK alone on any endpoints tested. CP plus proUK induced a significantly reduction in the atherosclerotic lesions, along with decreased levels of total cholesterol, triglyceride in the plasma. …”

Image_3_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

Image_3_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

The roles of miRNA-23a and IL-8 in the radioresistance of NPC cells. by Xin-Hui Li (447760)

“…<p>(A) and (B). A representative clonogenic survival assay shows that transfection of miRNA-23a mimic decreased the radioresistance of NPC CNE2-IR cells. …”

Image_1_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

The phosphorylation state of the CII domain regulates the ADP fraction in the CI domain by changing the ADP release rate, but not its affinity. by Joris Paijmans (3838486)

“…<p>(A) Cartoon that illustrates why the experiments rule out the latter “affinity” scenario. …”

Image_1_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

Image_2_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

Functional profiles of constructs illustrating the major effects of the L272A mutation. by Nicolas Bertheleme (5658055)

“…<p>The L272A mutation alone decreases constitutive activity on its own (Rag23.26) but this effect is overcome by the dominant effect of the F79A (Rag23.22). …”

Pairwise variation (V) analysis of the candidate reference genes based on <i>geNorm</i>. by Chunxiao Yang (665744)

“…The value V6/7 is higher than V5/6; this is due to the inclusion of a relative unstable sixth gene. Increasing variation in this ratio corresponds to decreasing expression stability.…”

Downregulation of miR-196a suppressed PANC-1 cell migration. by Fengting Huang (519721)

“…(D) Representative western blot analysis revealed that mesenchymal-epithelial transition contributed to suppression of PANC-1 cell migration after silencing miR-196a. After silencing miR-196a, E-cadherin expression increased, as well as expression of N-cadherin and Vimentin decreased.…”

Data_Sheet_1_Evaluating the Use of Mindfulness and Yoga Training on Forensic Inpatients: A Pilot Study.docx by Christina Spinelli (9752738)

“…Repeated measure ANOVAs found a significant increase in the describe facet of mindfulness (p = 0.03) with a large effect size (η_p² = 0.26) and a significant decrease in stress (p = 0.003) with a large effect size (η_p² = 0.39). …”

Differential expression of <i>gdf9</i> and <i>bmp15</i> at the primary oocyte and vitellogenic oocyte stages. by Guan-Chung Wu (841217)

“…<p><i>gdf9</i> and <i>bmp15</i> mRNA expression was detected by <i>in situ</i> hybridization (ISH) (A and B) and qPCR (C). Expression of <i>gdf9</i> was high at the primary oocyte stage and then gradually decreased as oocytes entered the secondary oocyte stage (A). …”

Protein Acylation Affects the Artificial Biosynthetic Pathway for Pinosylvin Production in Engineered <i>E. coli</i> by Jun-Yu Xu (2628595)

“…Oversupply of malonyl-CoA leads to an increase in malonylation level of global proteome as well as the enzymes in the artificial pathway, thereby decreasing yield of pinosylvin. …”

Table_1_miR-27a Downregulation Promotes Cutaneous Squamous Cell Carcinoma Progression via Targeting EGFR.XLSX by Yinghui Wang (581066)

“…It was found that miR-27a expression was significantly decreased in cSCC cells and tissues. in vitro and in vivo experiments showed that miR-27a inhibited cell proliferation and invasion of cSCC cells. …”