Oxidative injury is enhanced by inflammatory mediators (interleukins and TNF-α) as it provokes the activity of NADPH oxidase. by Mahmood Rasool (284425)

Image_9_Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson’s Disease.TIF by Mei-Fang Liu (5966561)

“…The results from animal experiments demonstrated that orexin-A attenuated the loss of dopaminergic neurons and the decrease of tyrosine hydroxylase (TH) expression in the substantia nigra, normalized the striatal dopaminergic fibers, and prevented the depletion of dopamine and its metabolites in the striatum. …”

Data_Sheet_1_The Response Patterns of Arbuscular Mycorrhizal and Ectomycorrhizal Symbionts Under Elevated CO2: A Meta-Analysis.docx by Yuling Dong (5364053)

“…The addition of N increased plant growth but decreased mycorrhizal fungal abundance, and P addition increased total plant biomass and extraradical hyphal length, but shoot biomass largely increased in low P conditions. …”

Cesarean section on a rise—Does advanced maternal age explain the increase? A population register-based study by Eva Rydahl (6260771)

“…Given the lack of impact of demographic and health risks on the relationship between maternal age and cesarean section, the authors suggest obstetric culture could be added to the list of risk factors for a cesarean. Future research on obstetric culture is recommended as are studies on a possible age-related decrease in the ability to maintain the progression of labor.…”

Shaped inputs required to eliminate residual oscillations from the linearized cart-pendulum system (Eqs 4–5), for different movement durations. by Salah Bazzi (11851767)

“…<p>It was assumed that the controller has a precise internal model of the system’s dynamics. …”

<i>Bcl2l10</i>, a new <i>Tpx2</i> binding partner, is a master regulator of <i>Aurora kinase A</i> in mouse oocytes by Su-Yeon Lee (378438)

“…<p>Previously, we demonstrated that <i>Bcl-2-like 10</i> (<i>Bcl2l10</i>) is associated with meiotic spindle assembly and that the gene that is most strongly down-regulated by <i>Bcl2l10</i> RNAi is <i>targeting protein for Xklp2</i> (<i>Tpx2</i>). <i>Tpx2</i> is a well-known cofactor that controls the activity and localization of <i>Aurora kinase A</i> (<i>Aurka</i>) during mitotic spindle assembly. …”

Results for four illustrative latent topics specified by a 50-topic CGC LDA model estimated from a corpus with 5,225 documents and a vocabulary of 28,971 words by DM Blei (19075)

“…CGC-based topic labels are a subset of the 50 × 500 topic annotation words that are unique to a topic and are words from the CGC vocabulary; these labels are ordered according to decreasing values. …”

image_4_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

image_2_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

image_3_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

image_5_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

image_7_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

image_6_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

image_1_The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling.pdf by Melissa N. van Tok (3190323)

“…Prophylactic treatment with anti-IL23R completely protected against the development of both spondylitis and arthritis, while vehicle-treated controls did develop spondylitis and arthritis. In a therapeutic study, anti-IL23R treatment failed to reduce the incidence or decrease the severity of experimental SpA. …”

Illustration of pri-miR-133a (A), pri-let7a (B) and pri-miR-29c (C) secondary structure changes caused by genetic variations. by Wei Zhang (405)

“…Three typical pri-miRNAs secondary structures (parts of them) were found to display increased (ΔΔG = −1.6 kcal/mol), unchanged (ΔΔG = 0 kcal/mol) and decreased stability of hairpin structures (ΔΔG = 1.6 kcal/mol) as a result of the genetic variations.…”

DataSheet1_Solar wind magnetosonic mach number as a control variable for energy dissipation during magnetic storms.pdf by Fatemeh Bagheri (6619298)

“…On the other hand, the dayside merging rate and the potential become sensitive to the solar wind density. This should result in a correlation between the intensity of the auroral electrojets and the solar wind density. …”

Characterization of <i>gprK</i> Encoding a Putative Hybrid G-Protein-Coupled Receptor in <i>Aspergillus fumigatus</i> by Mun-Gu Jung (3095184)

“…Notably, the absence of <i>gprK</i> results in reduced tolerance to oxidative stress and significantly lowered mRNA levels of the stress-response associated genes <i>sakA</i> and <i>atfA</i>. Activities of catalases and SODs are severely decreased in the Δ<i>gprK</i> mutant, indicating that GprK may function in proper activation of general stress response. …”

Image 1_Osteopontin as a diagnostic and NTZ-response biomarker of multiple sclerosis: a systematic review and meta-analysis.jpeg by Adela González-Jiménez (14607152)

“…Furthermore, the observed decrease of OPN levels after Natalizumab (NTZ) treatment evidenced its potential as a biomarker of its efficacy. …”

Table 1_Osteopontin as a diagnostic and NTZ-response biomarker of multiple sclerosis: a systematic review and meta-analysis.docx by Adela González-Jiménez (14607152)

“…Furthermore, the observed decrease of OPN levels after Natalizumab (NTZ) treatment evidenced its potential as a biomarker of its efficacy. …”

Table 2_Osteopontin as a diagnostic and NTZ-response biomarker of multiple sclerosis: a systematic review and meta-analysis.docx by Adela González-Jiménez (14607152)

“…Furthermore, the observed decrease of OPN levels after Natalizumab (NTZ) treatment evidenced its potential as a biomarker of its efficacy. …”