The ratio of APP localized in lipid rafts was decreased by reducing cholesterol levels using tebuconazole from CHO PS1 ΔE9 cells. by Yoon Young Cho (838272)

“…Cell lysates were used for discontinuous sucrose density gradient to fractionate into raft and non-raft fractions. (<b>a</b>) APP and caveolin levels from 12 fractions were measured using western blots. …”

Intravitreal ALF-186 decreased the IRI-induced capsase-3 and NF-κB mRNA expression and affected the heat-shock response differently. by Julia Stifter (4621033)

“…<p><b>(A)</b> Fold induction of caspase-3 mRNA expression after PBS, ALF-186, or iALF injection after IRI compared to GAPDH in relation to the corresponding non-ischemic contralateral retina analyzed by RT-PCR (n = 6; mean±SD; *** = p<0.001; *** = p<0.001). …”

Deficiency of G1 regulators P53, P21and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest-2 by Sharon Sheahan (38663)

“…As for all experiments the -null hepatocytes were obtained by infection at the time of plating of the hepatocytes of corresponding genotypes with adenovirus expressing Cre recombinase. (1) all deficient hepatocytes respond less well to inhibition of proliferation by TGFβ than control cells and deficient has the strongest effect. (2) and deficiency, singly or together have a similar effect on inhibition of proliferation by TGFβ. (3) deletion significantly reduces TGFβ-induced cell cycle arrest regardless of and status (compare control with ; - with with - and with TRPL). (4) double deficiency in and further decreases hepatocytes responses to TGFβ in term of regulation of proliferation, independently of status. (5) by contrast the effect of TGFβ on hepatocytes deficient in both and is not significantly different to that of null cells, and this is independent of status. …”

Increased NFKB2⁺ cells and decreased ACADM⁺ and ANGPTL4⁺ cells were observed in KIRC tissues. by Yu Zhang (12946)

“…<p>A. KIRC tissues from the local hospital showed increased NFKB2+ cells compared to paracarcinoma tissues. …”

Helminth infections are associated with decreased frequencies of mono- and multifunctional mycobacterial antigen-specific CD4⁺ Th17 cells in active TB. by Parakkal Jovvian George (517422)

Image_1_Donor Allospecific CD44high Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease.TIFF by Wei Huang (36889)

“…In this study, we sought to answer this question using a novel GVHD model induced by T cell receptor (TCR) transgenic OT-II T cells. …”

Helminth infections are associated with decreased frequencies of mono- and multifunctional mycobacterial antigen-specific CD4⁺ Th1 cells in active TB. by Parakkal Jovvian George (517422)

Dinaciclib decreases Mcl-1, Bcl-x_L and survivin levels, activates caspase-3 and induces apoptosis in thyroid cancer cells. by Shu-Fu Lin (126854)

image1_Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma.tif by Tingting Jia (770327)

A cluster-randomized crossover trial of organic diet impact on biomarkers of exposure to pesticides and biomarkers of oxidative stress/inflammation in primary school children by Konstantinos C. Makris (684176)

“…An initial increase was followed by a countervailing decrease over time in the organic period for OSI biomarkers 8-iso-PGF2a and MDA. …”

Synthesis, Characterization, and Catalase Activity of a Water-Soluble diMn^III Complex of a Sulphonato-Substituted Schiff Base Ligand: An Efficient Catalyst for H<sub>2</... by Claudia Palopoli (2168305)

“…Complex <b>1</b> is highly efficient to disproportionate H₂O₂ in an aqueous solution of pH ≥ 8.5 or in DMF, with only a slight decrease of activity. Electrospray ionization mass spectrometry, EPR, and UV–vis spectroscopy used to monitor the H₂O₂ disproportionation in buffered basic medium, suggest that the major active form of the catalyst during cycling occurs in the Mn^III₂ oxidation state and that the starting complex retains the dinuclearity and composition during catalysis, with the acetate that moves from bridging to terminal ligand. …”

Paf1, but not Ski8, depletion leads to strong accumulation of PolII downstream of the TSS of genes with up-regulated intronic APA. by Yan Yang (33204)

“…<p><b>(A)</b> The average enrichment profiles of PolII after depletion of Paf1 or Ski8. …”

A funnel plot shows the number of studies reporting a change in gut bacteria abundance in patients with an RTI compared to healthy participants. by Claire A. Woodall (10724917)

“…There were 5/5 reports of an ‘increase’ in <i>Enterococcus</i>, 5/5 reports of a ‘decrease’ in Ruminococcaceae and 6/6 reports of a ‘decrease’ in both Lachnospiraceae and <i>Ruminococcus</i> in patients with an RTI compared to healthy participants. …”

Reduction Pathway of End-On Terminally Coordinated Dinitrogen. IV. Geometric, Electronic, and Vibrational Structure of a W(IV) Dialkylhydrazido Complex and Its Two-Electron-Reduced... by Kay H. Horn (2684512)

“…In <b>B</b>^W, the N−N force constant decreases to 6.4 mdyn/Å, which is between the values found for the Mo/W NNH₃ and NNH₂ complexes. …”

The effect of NAC on decreased ERK1/2 Tyr-204 phosphorylation caused by arecoline during myogenic differentiation in C2C12 cells. by Yi-Xuan Li (6633845)

Decreased numbers of cells positive for Ki67 and BrdU in nodules of MB allograft treated with AAV-<i>Tis21</i> viral particles. by Dario Presutti (828288)

Decreased expression of Nrf2 related genes and stemness markers in Nrf2 knocked down resistant Huh7 cells treated with siRNA. by Luping Gao (4269754)

PHA increased anti-oxidant gene expression and decreased NADPH oxidase and phospho-NF-kB p65⁺ microglia/macrophages. by Zhenying Han (621634)

Quantification of <i>ATP5B</i> mRNA and β-F1-ATPase protein expression shows decreased protein translation in obesity. by Lee Tran (2106961)

CRP decreases histone H4-enhanced IAV aggregation, as well as IAV neutralizing activity and increased neutrophil uptake of IAV caused by H4. by I-Ni Hsieh (4971679)