Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and Bioassays by Antonio Lavecchia (1264989)

“…Here, we report findings that frataxin is degraded via the ubiquitin–proteasomal pathway and that it is ubiquitinated at residue K¹⁴⁷ in Calu-6 cells. A theoretical model of the frataxin-K¹⁴⁷/Ub complex, constructed by combining bioinformatics interface predictions with information-driven docking, revealed a hitherto unnoticed, potential ubiquitin-binding domain in frataxin. …”

The Populus MYB transcription factor <i>PSAR1</i> negatively regulates salt stress and is a repressor of ABA signaling by Qing Fang (254280)

“…Whereas by higher ABA (5.0 μM) treatment a delayed blooming was viewed in the OeLAs seedlings. …”

Table_1_Oral Microbiota Profile in a Group of Anti-AChR Antibody–Positive Myasthenia Gravis Patients.XLSX by Chao Huang (109404)

Intestinal NF-κB and STAT signalling is important for uptake and clearance in a <i>Drosophila-Herpetomonas</i> interaction model by Lihui Wang (437861)

“…This network of signalling may represent a general mechanism with which dipteran respond to trypanosomatids.…”

Resistance to Streptozotocin-Induced Autoimmune Diabetes in Absence of Complement C3: Myeloid-Derived Suppressor Cells Play a Role by Xiaogang Gao (423327)

“…We hypothesize that myeloid-derived suppressor cells (MDSC), which act as regulators in autoimmunity, play a role in resistance to diabetes in absence of complement C3. …”

Two-parameter distributions show a more confined distribution of the Class IV parameter sets than the Class III sets. by Xiangyu Yao (3203703)

“…As the mean degradation rate, <i>k</i>_dgrd, decreases, fewer Class IV parameter sets are found in a more confined region.…”

DataSheet1_Drastic Ce3+ Insertion Enhancement in YAG Garnet Nanocrystals Through a Solvothermal Route.pdf by Alexandra Cantarano (9611916)

“…The internal quantum yield reaches 40 ± 5% before decreasing due to concentration quenching. The nanocrystal brightness, which combines the internal quantum yield and the cerium concentration, has been found optimal for a doping of 2 mol.% Ce³⁺.…”

Supplementary file 1_The role of mental accounting in risk-taking and spending: a meta-analysis of the house-money effect.docx by Kasumi Dan (21661496)

“…Introduction<p>This study systematically analyzes the house-money effect, a phenomenon in which people become more financially risk-taking and wasteful after receiving unexpected income. …”

Effects of spinal stabilization exercises delivered using telerehabilitation on outcomes in patients with chronic neck pain: a randomized controlled trial by Dilara Onan (14826612)

“…Patients performed SSE 3 days a week, for 8 weeks. The TRG was instructed remotely while the CG was instructed in the clinic.…”

Table1_4′-phosphopantetheine acts as a potential antioxidant to limit atherosclerotic plaque formation by inhibiting ROS generation.DOCX by Taiyu Zhai (13991868)

“…In the study, a plasma metabolite, 4′-Phosphopantetheine (4-PPanSH), which was discovered by HPLC-MS/MS, as peripheral blood 4-PPanSH decreases, the degree of coronary blockage gradually aggravates. …”

Two-parameter distributions show a more confined distribution of the Class I parameter sets than the Class II sets. by Xiangyu Yao (3203703)

“…As the mean degradation rate, <i>k</i>_dgrd, decreases, fewer Class I parameter sets are found in a more confined region.…”

A General Model for Toxin-Antitoxin Module Dynamics Can Explain Persister Cell Formation in <i>E. coli</i> by Lendert Gelens (451747)

“…Finally, increases in the antitoxin degradation rate and decreases in the bacterial growth rate cause a rise in the amount of persisters during nutritional stress.…”

Some mRNA species are more susceptible to oxidative damage in SOD1^G93A mice. by Yueming Chang (62156)

“…These oxidized mRNA species are significantly decreased in vitamin E treated SOD1^G93A mice (<i>G93A+vitE</i>). …”

Sternocleidomastoid muscle activation following inspiratory muscle training in patients with chronic obstructive pulmonary disease: a randomized clinical trial by Diogo Fanfa Bordin (10420682)

“…People with COPD participating in a lung rehabilitation program were allocated to a control or inspiratory muscle training (IMT) group. …”

Table1_Strategies for Improving Postpartum Contraception Compared With Routine Maternal Care: A Systematic Review and Meta-Analysis.PDF by Denghui Hu (15215188)

“…<p>Objectives: This study aimed to systematically review the effectiveness of service interventions for improving postpartum contraception, including contraceptive use, prevention of repeat pregnancies and induced abortions.</p><p>Methods: A systematic literature search was conducted in three databases until June 2022 (PROSPERO registration CRD42022328349). …”

Table_1_Causal association between gut microbiota and hyperemesis gravidarum: a two-sample Mendelian randomization study.docx by Dinglin Xu (18293845)

“…Additionally, the genus Coprococcus2 was related to a decreased risk of HG. Sensitivity studies validated the strength and reliability of the link between the composition of the GM and HG. …”

Effects of hNGFP61S/R100E on Aβ plaque load revealed by immunohistochemistry, Thioflavin S staining and ELISA. by Simona Capsoni (161132)

“…(<b>C,F</b>) The intranasal administration of 540 ng/kg of hNGFP61S/R100E decreases the plaque load. (<b>G,H</b>) The treatment with hNGFP61S/R100E determined a shift from fibrillar (<b>G</b>) to more compact morphology of the remaining plaques (<b>H</b>). …”

Synergistic Effect of Adsorption and Enzymatic Conversion in the Bisphenol-A Removal by Laccase Immobilized on Poly(glycidyl methacrylate-co-ethyleneglycol dimethacrylate) by Claudinei F. Melo (4648084)

“…The immobilized laccase was used for removal of bisphenol-A (BPA) from aqueous solution. The temperature effect was significant on activity, but insignificant on BPA removal by the immobilized laccase. …”

Table 1_Can digital technology use enhance livelihood capital for mining farmers? A moderated mediation model.xlsx by Xuesong He (292081)

“…Collective action plays a mediating role in the relationship of this impact path. …”

Supplementary Material for: Leber hereditary optic neuropathy “plus” with the m.14487 T>C mutation as the causality of hemidystonia: A Case Report by Takano F. (20180505)

“…Introduction: LHON complicated with extraocular symptoms is called LHON plus. We describe a case of Leber hereditary optic neuropathy (LHON) plus with a rare mutation, that also caused dystonia. …”