Data_Sheet_1_Iron-Deficiency Anemia Results in Transcriptional and Metabolic Remodeling in the Heart Toward a Glycolytic Phenotype.docx by Yu Jin Chung (10013939)

“…Our results show that iron-deficiency anemia results in a metabolic remodeling toward a glycolytic, lactic acid-producing phenotype, a hallmark of hypoxia.…”

Phosphatidylinositol 3-Kinase Plays a Vital Role in Regulation of Rice Seed Vigor via Altering NADPH Oxidase Activity by Jian Liu (33711)

“…Furthermore, the western blot analysis of OsRac-1 demonstrated that the translocation of Rac-1 from cytoplasm to plasma membrane, which was known as a key factor in the assembly of NADPH oxidase, was suppressed by treatment with PI3K inhibitors, resulting in the decreased activity of NADPH oxidase. …”

Impact of Cu(II) Binding on Structures and Dynamics of Aβ₄₂ Monomer and Dimer: Molecular Dynamics Study by Pham Dinh Quoc Huy (2944638)

“…The simulation of dimers was conducted with the Cu­(II)/Aβ stoichiometric ratios of 1:1 and 1:2. For the 1:1 ratio Cu­(II) delays the Aβ dimerization process as observed in a number of experiments. …”

Supplementary file 1_Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study.docx by Carlos A. R. Sánchez (21288050)

Data_Sheet_1_The Epidemiology of Ground Glass Opacity Lung Adenocarcinoma: A Network-Based Cumulative Meta-Analysis.docx by Xiongfei Li (9147545)

“…</p><p>Methods: We retrieved all solitary GGO adenocarcinoma lung cancer (ADLC) on the PubMed, Cochrane Library, and Embase databases until January 1, 2019 and extracted the general information to perform the meta-analysis, mainly focusing on age, gender, and smoking status.</p><p>Results: A total of 8,793 solitary GGO ADLC patients from 53 studies were included in this analysis. …”

Table_1_Percutaneous stent implantation for occluded central shunts in adults: A case report and review of current evidence.DOCX by Yaser Jenab (14146713)

“…We also reported the case of a 33-year-old man with cyanotic CHD and a occluded central aorto-pulmonary shunt, who was successfully treated with percutaneous balloon dilatation and subsequently stent implantation at our institution.…”

Repeated elicitations of <i>N. attenuata</i> leaves at the scale of a feeding, early-instar <i>M. sexta</i>. by William Stork (374001)

“…Conjugation requires both <i>Na</i>TD and <i>Na</i>JAR4; silencing <i>Na</i>JAR4 and <i>Na</i>TD transcript accumulation decreases TPI activity <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004697#pone.0004697-Wang1" target="_blank">[25]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004697#pone.0004697-Kang1" target="_blank">[30]</a>. …”

Data_Sheet_1_Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System.zip by Sarah E. Mann (8692515)

“…This allows for the combination of multiple T-hybridoma lines within a single reaction. Sensitivity to stimulation is not decreased by adding fluorescent proteins or multiplexing T cells. …”

Table_1_A Cost-Effectiveness and Quality of Life Analysis of Different Approaches to the Management and Treatment of Localized Prostate Cancer.DOCX by Aleksandra Harat (813785)

“…Microsimulations of radical prostatectomy, 3D-conformal radiotherapy, or active monitoring were performed using Medicare reimbursement schedules and clinical trial results for a target population of men aged 50–69 years with newly diagnosed localized prostate cancer (T1-T2, NX, M0) over a time horizon of 10 years. …”

Impact of Cu(II) Binding on Structures and Dynamics of Aβ₄₂ Monomer and Dimer: Molecular Dynamics Study by Pham Dinh Quoc Huy (2944638)

“…The simulation of dimers was conducted with the Cu­(II)/Aβ stoichiometric ratios of 1:1 and 1:2. For the 1:1 ratio Cu­(II) delays the Aβ dimerization process as observed in a number of experiments. …”

Data_Sheet_1_Assessing the association between age at first sexual intercourse and migraine: a Mendelian randomization study.docx by Guoliang Zhu (4726623)

“…Stratified analyses provided suggestive evidence of the causal relationship between delayed AFS and a decreased risk of migraine for both males (OR = 0.71, 95% CI [0.59 to 0.84]) and females (OR = 0.73, 95% CI [0.61 to 0.89]). …”

Data_Sheet_1_Impact of a combination sound therapy on tinnitus distress: an exploratory one-year longitudinal study.docx by Dina Lelic (11051240)

“…The degrees of improvement in THI, TFI and tinnitus annoyance were correlated with daily hours of sound-therapy use but not with daily hours of amplification-only or total device use.</p>Conclusions<p>A combination sound therapy consisting of therapy sounds, amplification as needed, and counseling was associated with a reduction in tinnitus-related distress. …”

Video_4_Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model.MP4 by Sepideh Mostafavi (11561719)

“…Remodeling of mitochondria and metabolism, with the shift from glycolysis to oxidative phosphorylation (OXPHOS), plays a fundamental role in maintaining pluripotency and stem cell fate. …”

DataSheet1_A framework for computer-aided high performance titanium alloy design based on machine learning.pdf by Suyang An (18371967)

“…However, traditional material design methods encounter numerous calculations and experimental trial-and-error processes, leading to increased costs and decreased efficiency in material design. The data-driven model presents an intriguing alternative to traditional material design methods by offering a novel approach to expedite the materials design process. …”

PPA1 Regulates Systemic Insulin Sensitivity by Maintaining Adipocyte Mitochondria Function as a Novel PPARγ Target Gene by Ye Yin (420350)

“…<a>Downregulation of mitochondrial function in adipose tissue is considered as one important driver for the development of obesity-associated metabolic disorders. …”

Table_3_ΔFosB is part of a homeostatic mechanism that protects the epileptic brain from further deterioration.DOCX by Jerome Clasadonte (17777424)

“…Furthermore, prolonged inhibition of ΔFosB using a ΔJunD construct to block ΔFosB signaling in a mouse model of Alzheimer’s disease, that exhibits spontaneous recurrent seizures, led to similar findings, with increased neuroinflammation and decreased NPY expression in mossy fibers. …”

Table4_Global Burden of Inflammatory Bowel Disease Among Children and Adolescents: A Comprehensive Analysis (1990–2019).XLSX by Xuejie Chen (1408159)

“…During the same period, the DALY numbers decreased by 53.5%, from 243,081.06 to 113,119.86, with all SDI regions experiencing a clear drop in DALYs except high SDI regions. …”

Interferon alpha-inducible protein 27 (IFI27) is a prognostic marker for pancreatic cancer based on comprehensive bioinformatics analysis by Shu Huang (1817500)

“…Analysis of infiltrating immune cells displayed that higher expression of IFI27 expression correlates with decreased CD8 + T cells and increased M2 macrophages in the tumor immune microenvironment (TIME), then biochemical analyses of a mouse model and immunohistochemical (IHC) staining verified that glycolytic enzymes and M2 macrophages increased significantly in pancreatic cancer tissues. …”

DataSheet_1_Increased Adaptive Variation Despite Reduced Overall Genetic Diversity in a Rapidly Adapting Invader.docx by Daniel Selechnik (6930500)

“…Nonetheless, toads encounter novel environmental challenges in Australia, and the transition between genetic clusters occurs at a point along the invasion transect where temperature rises and rainfall decreases. …”

Functional Assays and Metagenomic Analyses Reveals Differences between the Microbial Communities Inhabiting the Soil Horizons of a Norway Spruce Plantation by Stéphane Uroz (281637)

“…In this context, the long-term differentiation of the forest soils into horizons may impact the assembly and the functions of the soil microbial communities. To gain a more comprehensive understanding of the ecology and functional potentials of these microbial communities, a suite of analyses including comparative metagenomics was applied on independent soil samples from a spruce plantation (Breuil-Chenue, France). …”