Table2_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.DOCX by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Table_1_Tourism experiences reduce the risk of cognitive impairment in the Chinese older adult: a prospective cohort study.DOCX by Qian Li (114642)

“…Cox regression showed that tourism decreased the risk of cognitive impairment (aHR = 0.69, 95% CI: 0.41–0.62) when adjusted for behavioral covariates and characteristics. …”

Table_4_Inflammatory cytokines and stroke and its subtypes: a genetic correlation and two-sample Mendelian randomization study.XLSX by Yu Guo (102701)

“…Our findings suggest that decreased IL-17 levels could potentially be linked to a higher likelihood of intracerebral hemorrhage (ICH) (OR = 0.51, 95% CI: 0.28–0.93, p = 0.028). …”

Image1_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.JPEG by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Table2_Risk of drug-induced angioedema: a pharmacovigilance study of FDA adverse event reporting system database.xlsx by Maoxia Fan (16914033)

“…After categorizing the drugs, the strongest positive signal was observed in the antithrombotic agents [ROR (95% CI): 22.53 (21.16–23.99)], following that, cardiovascular drugs [ROR (95% CI): 9.17 (8.87–9.48)], antibiotics [ROR (95% CI): 6.42 (5.91–6.96)], immunosuppressors [ROR (95% CI): 5.95 (5.55–6.39)], anti-inflammatory analgesics [ROR (95% CI): 4.65 (4.45–4.86)], antiallergic drugs [ROR (95% CI): 4.47 (3.99–5)], antiasthmatics [ROR (95% CI): 2.49 (2.14–2.89)], blood sugar control drugs [ROR (95% CI): 1.65 (1.38–1.97)], and digestive system drugs [ROR (95% CI): 1.59 (1.45–1.74)] exhibited progressively decreasing ROR values.</p>Conclusion<p>Many medications are associated with a high risk of angioedema. …”

Datasheet3_Assessing disparities through missing race and ethnicity data: results from a juvenile arthritis registry.pdf by Katelyn M. Banschbach (19204348)

“…Black patients had a significantly higher odds ratio of having a clinical juvenile arthritis disease activity score (cJADAS10) of ≥5 at first follow-up compared with White patients. …”

Table3_Ureteropelvic junction obstruction in infants: Open or minimally invasive surgery? A systematic review and meta-analysis.doc by Valentina Cascini (14162511)

“…Minimally invasive surgery (MIS) procedures, including laparoscopic pyeloplasty (LP) and robot-assisted laparoscopic pyeloplasty (RALP), have been reported to achieve better outcomes (i.e., decreased morbidity, reduced postoperative pain, superior esthetic results, and shortened length of hospital stay, LOS), with a success rate similar to OP. …”

Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx by Zewudu Andualem (8602434)

“…</p>Results<p>A total of 21 studies with 10,785 participants were included, the pooled prevalence of chronic respiratory health was 39% (95% CI: 31–48%). …”

Table_2_Investigation of the causal association between Parkinson’s disease and autoimmune disorders: a bidirectional Mendelian randomization study.docx by Junyi Yang (602557)

“…</p>Results<p>Our MR findings suggested that genetically predicted higher liability to PD was causally associated with a decreased risk of irritable bowel syndrome (OR = 0.98; 95% CI: 0.96-0.99; P = 0.032). …”

7SL-sRNA can be detected by directly from serum using a one-step RT-qPCR. by Stephen M. Chiweshe (6377585)

“…<p>A) Serum samples from a <i>T</i>. <i>brucei</i> infected cow (animal 6632, <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0007189#pntd.0007189.g004" target="_blank">Fig 4</a>) were directly applied to a one-step RT-qPCR reaction, and the results compared to the two-step RT-qPCR reaction and parasitaemia scoring by microscopy. …”

Table 1_Efficacy and safety of levetiracetam in preventing postoperative seizures in adult patients with brain tumors: a meta-analysis.docx by Yongyi Zhang (1800337)

“…In addition, levetiracetam induced only minor adverse effects, with a lower occurrence rate of adverse reactions than phenytion sodium and valproate. …”

DataSheet_1_A Novel Tree Shrew Model of Chronic Experimental Autoimmune Uveitis and Its Disruptive Application.pdf by Kaijiao Hu (8978402)

“…RGS4 inhibition and dihydroartemisinin could significantly alleviate the retinal pathological injuries of IRBP_1197-1211-induced EAU by decreasing the expression of CD4 T-cells.</p>Conclusion<p>Our study provides a novel chronic EAU in tree shrews elicited by bovine R14 and tree shrew IRBP_1197-1211 characterized by retinal degeneration, retinal damage with subretinal Aβ deposits and microglia/macrophage infiltration, and T-cell response, probably by altering important pathways and genes related to bacterial invasion, inflammatory pain, microglial phagocytosis, and lipid and glucose metabolism. …”

Table1_Bifidobacterium Strains Present Distinct Effects on the Control of Alveolar Bone Loss in a Periodontitis Experimental Model.pdf by Natali Shimabukuro (11475286)

“…Administration of both bifidobacteria resulted in serum IL-10 decreased levels. Our data indicated that the beneficial effect of Bifidobacterium is not a common trait of this genus, since B. breve 110^1A induced an inflammatory profile in gingival tissues and did not prevent alveolar bone loss. …”

Table_1_Enhanced Recovery Care vs. Traditional Care in Laparoscopic Hepatectomy: A Systematic Review and Meta-Analysis.DOCX by Xueyin Zhou (12271712)

“…</p>Aim<p>We aimed to perform a meta-analysis to evaluate the safety and efficacy of enhanced recovery after a surgery program in laparoscopic hepatectomy.…”

Data Sheet 1_Efficacy and safety of topical minocycline preparations for papulopustular rosacea: a systematic review and meta-analysis.pdf by Awadh Alamri (20970752)

“…Background<p>Rosacea is a chronic inflammatory skin condition. Papulopustular rosacea (PPR), one of the subtypes of rosacea, presents with papules and pustules (Pelle, 2008). …”

Apparent Anti-Woodward–Hoffmann Addition to a Nickel Bis(dithiolene) Complex: The Reaction Mechanism Involves Reduced, Dimetallic Intermediates by Li Dang (1393051)

“…Recent studies of the ligand-based reactions of Ni­(tfd)₂ (tfd = S₂C₂(CF₃)₂) and its anion [Ni­(tfd)₂]⁻ with alkenes (ethylene and 1-hexene) showed that in the absence of the anion, the reaction proceeds most rapidly to form the intraligand adduct, which decomposes by releasing a substituted dihydrodithiin. However, the presence of the anion increases the rate of formation of the stable <i>cis</i>-interligand adduct, and decreases the rate of dihydrodithiin formation and decomposition. …”

DataSheet_1_The prolonged effect of film mulch and P application on lucerne forage yield in a semiarid environment.docx by Meng Kong (1287318)

“…</p>Methods<p>This study conducted a 9-year field experiment on the semiarid Loess Plateau to investigate how film mulch and P application affect lucerne forage yield, soil water content, and soil fertility. …”

Table1_Clinical and laboratory features of childhood-onset primary Sjögren's syndrome: A retrospective study from China.docx by Chenxi Liu (286325)

“…We aimed to improve the diagnosis and evaluation of C-pSS by summarizing its clinical and laboratory features.</p>Methods<p>A total of 49 patients with C-pSS between July 2015 and August 2022 in the Department of Rheumatology and Immunology of Shanghai Children's Medical Centre were enrolled in this study. …”

Crystal Structure, Charge-Transfer-Induced Spin Transition, and Photoreversible Magnetism in a Cyano-Bridged Cobalt−Tungstate Bimetallic Assembly by Shin-ichi Ohkoshi (1396678)

“…However, <b>2</b> did not exhibit such a phase transition. When the LT phase of <b>1</b> was irradiated by 840 nm light, ferromagnetism with a Curie temperature of 40 K and magnetic coercive field of 12 kOe were observed. …”

Table 1_Evaluation of microsatellite instability patterns in mismatch repair deficiency: a retrospective analysis of 285 endometrial cancers.docx by Cheng Wang (102692)

“…However, based on the minimal shifting criteria, 13 cases with MSI-L were reassessed as MSI-H because of the occurrence of minimal microsatellite shifts, and the inconsistency rate between MMR-IHC and MSI-PCR decreased to 7.7% (22/285). Additionally, discordant cases showed a higher frequency (91%, 20/22 cases) of minimal shift involving the mononucleotide locus. …”