O-GlcNAcylation and ubiquitination of A20 modulate its expression. by Gautam V. Shrikhande (227350)

“…(F) WB analysis of total and phospho-A20 in SMC cultured in 5, 15 and 30 mM D-Glu and treated with TNF for 6 h demonstrated that relative phosphorylation levels of A20 (pA20) were not decreased by high glucose, despite decreased TNF-mediated upregulation of A20 protein in cells cultured in high glucose. …”

Domain architecture of DLAR and PTP99A RPTPs. by Lalima L. Madan (205695)

“…While the D2 domain of DLAR decreases the activity of its D1 domain, the D2 domain of PTP99A causes an apparent increase in the activity of its D1 domain.…”

Induction of IL-17A production during <i>C. neoformans</i> strain H99γ infection requires IFN-γR expression. by Karen L. Wozniak (229721)

“…A. Asterisks (*) indicate where significant decreases in CFU were observed in IFN-γR ^−/− mice compared to wild-type BALB/c mice (<i>P</i><0.01). …”

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes by Fatih Abasiyanik (4721253)

Disruptions of telomere function in the G9a-KD and the SUV-KD cells. by Yutaka Kondo (35816)

“…C, Expression level of hTERT was measured by real-time PCR. hTERT expression is decreased in the G9a-KD cells compared to those in the control PC3 and the SUV-KD cells. …”

Effect of let-7a on tumorigenicity in xenograft models. by Qingchuan Dong (250327)

“…(<b>B</b>) Western blotting showed that the expression of E2F2 and CCND2 decreased dramatically in tumors excised from PC3-let-7a-GFP-tumor-bearin mice compared to those with PC3-GFP tumors. β-actin was used as an internal control. …”

Characteristics of hub genes. A- Expression of hub genes. by Sarah Djebali (189529)

“…</i>, hubs, non-hubs, and all RACEd genes), the proportion of genes having a detected ortholog in each eukaryotic species represented on the X axis (ordered by decreasing phylogenetic distance from human) is reported on the Y axis. …”

IFN-γ counter-regulates hepatic fetuin-A expression. by Wei Li (7081)

“…<p><b>A</b>). <i>IFN-γ decreased fetuin-A expression levels in hepatocytes</i>. …”

Mutational analysis of GBV-C 152–167 NS5A peptide. by Jinhua Xiang (93812)

“…HIV replication was significantly decreased in Jurkat cell lines expressing full-length NS5A (1–414), the 152–167 peptide, and the S158E mutant (*) compared to all other cell lines on days 5, 6, and 7 days post-infection (panel C). …”

Id2 down regulation drives Neuro2a AD cells towards the AI phenotype. by Lina Chakrabarti (501389)

“…<p>(<b>A, B</b>) BrdU incorporation assay demonstrated that transfection of AD cells with Id2-siRNA reduced the rate of proliferation. …”

Knockdown of CN-A attenuate the protein synthesis inhibition under ER stress. by Mariana Bollo (244365)

“…Note that CN is decreased by the CN-A morpholinos treatment only after ER stress (lane M-tg 6). …”

Voltage in the steady state of the membrane system as a function of higher concentration for configurations A (black) and B (red). by Sławomir Grzegorczyn (12035398)

LTP modulates steady-state inactivation of A-type K⁺ currents. by Sung-Cherl Jung (261358)

“…Scale bars, 200 pA, 50 ms. The A-current available for activation at −60 mV was significantly decreased only in the neurons receiving paired stimulation 10 min after conditioning stimulation (a red arrow). …”

Regulation of bta-miRNA29d-3p on lipid accumulation via GPAM in dairy cow mammary epithelial cells by Dawei Yao (14003604)

“…Increasing evidence has identified that miR-29 is a key regulator of cholesterol and fatty acid synthesis. …”

Proposed model of miR-199a-5p profibrotic function in lung fibrogenesis. by Christian Lacks Lino Cardenas (282070)

“…The clathrin-coated pit pathway (red arrows) increases TGFβ signal transduction leading to the activation of lung fibroblasts and ultimately lung fibrosis whereas the CAV1 lipid raft pathway (green arrows) mediates TGFβ/TGFβR complex degradation, thus decreasing TGFβ signaling and preventing lung fibrosis <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003291#pgen.1003291-Rosenbloom1" target="_blank">[73]</a>. …”

Supporting data for thesis “Therapeutic Effects of Ganoderma and Its Active Ingredients on Microglial Activation and Polarization in Multiple Sclerosis Treatment” by Lu Zhang (9067643)

“…<p dir="ltr">Supporting data for thesis “Therapeutic Effects of Ganoderma and Its Active Ingredients on Microglial Activation and Polarization in Multiple Sclerosis Treatment”</p><p dir="ltr">Multiple Sclerosis (MS), a neurodegenerative disease infecting the central nervous system (CNS), without an effective therapeutic strategy currently. …”

Supplementary Material for: The Release of Cyclophilin A from Rapamycin-Stimulated Vascular Smooth Muscle Cells Mediated by Myosin II Activation: Involvement of Apoptosis but Not A... by Su Z. (3222573)

“…<b><i>Introduction:</i></b> The exocytosis of cyclophilin A (CyPA) by a vesicular pathway in response to reactive oxygen species has been determined. …”

Binding of PregOBP56a to <i>N</i>-phenyl-1-naphthylamine (1-NPN) and potential ligands derived from chicken meat. by Yuko Ishida (104789)

“…F, Binding of PregOBP56a to various ligands at pH 5. The binding affinity of stearic acid decreased to same level as decanoic acid, palmityl acetate, and cholesterol. …”

A Multifactorial Weight Reduction Programme for Children with Overweight and Asthma: A Randomized Controlled Trial by Maartje Willeboordse (473349)

“…Analyses were performed with linear mixed models for longitudinal analyses.</p><p>Results</p><p>After 18 months, the body mass index-standard deviation score decreased by -0.14±0.29 points (p<0.01) in the intervention group and -0.12±0.34 points (p<0.01) in the control group. …”

NFAT does not appear to be involved in latent HIV transcription in 5A8 cells. by Jonathan K. Chan (586472)

“…<p><i>A,</i> immunoblotting analysis of RelA and NFAT knockdowns in 5A8 cells. …”