Section A represents a randomised trial of IL6RA therapy with both normal IL-6 signalling and the effect of intervention. by Fergus W. Hamilton (10724401)

Proteinuria increases in proportion to podocyte number per glomerular tuft and podocyte density decrease. by Larysa Wickman (3169548)

“…<p><b>Panel A:</b> Urine PCR shown on a linear scale in relation to podocyte density demonstrating that as podocyte density decreases below approximately 100 per 10⁶ um³ the level of proteinuria exponentially increases. …”

Dnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma by Staci L. Haney (3186831)

“…Interestingly, transcriptomes of <i>Dnmt3a</i>^<i>+/-</i> and <i>Dnmt3a</i>^<i>Δ/Δ</i> lymphomas were largely conserved and significantly overlapped with those of human tumors. …”

Heatmaps depicting the dynamics over time of the distribution of cellulose polymer degrees of polymerization (DP) for a default microfibril. by Eric Behle (11426692)

Data_Sheet_1_Ultra-processed food consumption is associated with increase in fat mass and decrease in lean mass in Brazilian women: A cohort study.pdf by Lívia Carolina Sobrinho Rudakoff (12829580)

“…There was an association between ultra-processed food consumption and increase in body mass index, body fat percentage, fat mass index, android fat and gynoid fat and decrease in lean mass percentage, only in women.</p>Conclusion<p>A high ultra-processed food consumption is associated with a long-term increase in fat mass and a decrease in lean mass in adult women.…”

FBA-TPQ preferentially decreases cell viability and growth of A2780 and OVCAR-3 cells but not normal IOSE-144 cells. by Tao Chen (75911)

Subjects:

Mechanism study on a plague outbreak driven by the construction of a large reservoir in southwest china (surveillance from 2000-2015) by Xin Wang (91924)

“…</p><p>Methodology/Principal findings</p><p>We studied a plague outbreak caused by the construction of a large reservoir in southwest China followed 16-years’ surveillance.…”

The Effect on Mental Health of a Large Scale Psychosocial Intervention for Survivors of Mass Violence: A Quasi-Experimental Study in Rwanda by Willem F. Scholte (210542)

“…We studied the effect on mental health of a large scale psychosocial intervention primarily aimed at social bonding in post-genocide Rwanda. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Additionally, we found that a large concentration of negative charge at the surface of the POPA-based membrane greatly increased the number of contacts with lipid molecules and significantly decreased the exposure of intracellular NKG2A ITIM regions to water molecules, thus likely halting the signal transduction process. …”

Changes in optic nerve head blood flow following eye drop administration in a representative case. by Nana Takahashi (9999164)

“…In the brinzolamide and brimonidine fixed combination (BBFC) group, a suppression of diurnal fluctuation-induced decreases in optic nerve head blood flow was observed 6 hours after administration compared to the baseline.…”

<i>USP28</i> protein level was decreased by hypoxia signaling via both protein degradation and transcriptional repression in A549 cells. by Qin Li (36669)

“…After treatment, cells were lysed and 50 µg of whole cell lysate was analyzed by Western blotting. (C) Hypoxia decreased <i>USP28</i> mRNA levels in A549 cells. A549 cells were cultured in 1% O₂ for 24 hr. …”

Loss of TPD3 Leads to a Decreased Serine/Threonine Phosphatase Activity and Altered Substrate Specificity of the PP2A C Subunit by Hans Hombauer (75199)

A systematic review into the: effect of feeding food rich in cyp2a6 and glutathione enzymes on decreasing nicotine level in the body of smokers by Dani Nasirul Haqi (14159056)

Reduced RAB27A expression in melanocytes significantly decreases the melanin content in the epidermis, resulting in a lighter skin surface color of HSS. by Yasuko Yoshida-Amano (314746)

Subjects:

(A-C) Force versus drill depth and torque versus drill depth. by Marsel Ganeyev (21453399)

FL sublines exhibit greater cell growth potential than parental cells on low-binding cultures. by Tomoyuki Nakano (169130)

“…Note that H441 cells actually showed a slight decrease in DNA during the 7 days in a detachment culture. …”

Associations between location and decreasing CRF tertiles and increasing MRS tertiles. by Kayne McCarthy (793339)

Associations of short-term exposures to downward temperature shifts (temperature variability) with (A) total MI, (B) STEMI, and (C) NSTEMI hospital admissions at lag 0–6 days. by Wenli Ni (5720498)

Associations of short-term exposures to upward temperature shifts (temperature variability) with (A) total MI, (B) STEMI, and (C) NSTEMI hospital admissions at lag 0–6 days. by Wenli Ni (5720498)

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction by Jin Chai (183630)

“…</p><p>Conclusions</p><p>The levels of hepatic detoxification enzymes were significantly decreased in human obstructive cholestasis, and these decreases were positively associated with a marked reduction of FXR levels. …”