Data - Climate change impacts on Lactuca sativa.xlsx by Nicholas Yos (21507818)

“…Climate change-induced shifts in these environmental conditions have the potential to significantly affect nearly all terrestrial plants. A number of studies have explored the impacts of changing one or two of the conditions listed above, but few have examined the combined effects of all three. …”

DataSheet1_Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem—implications for channelopathies.pdf by Salma Allam (16836396)

“…Interestingly, fast-inactivating channels, including Familial Hemiplegic Migraine mutants, are more potently inhibited than WT channels, while slow-inactivating channels, such as those expressed with the Cavβ_2a auxiliary subunit, are spared. We found similar results in L-type channels, and, remarkably, Timothy Syndrome mutant channels were insensitive to Gem inhibition. …”

Image_3_Microbial communities are thermally more sensitive in warm-climate lizards compared with their cold-climate counterparts.TIF by Xia-Ming Zhu (8601639)

“…To elucidate the role of gut microbiota in thermal adaptation, we designed a 2 species × 3 temperatures experiment, whereby we acclimated adult males of two agamid lizard species (warm-climate Leiolepis reevesii and cold-climate Phrynocephalus przewalskii) to 20, 28, and 36°C for 2 weeks and then collected their fecal and small-intestinal samples to analyze and compare the microbiota using 16S rRNA gene amplicon sequencing technology. …”

DataSheet1_Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.ZIP by Zimengwei Ye (13757419)

“…These effects may be linked to the stimulation of GLUT4 expression and translocation via regulating AMPKα/SIRT1/PGC-1α signaling pathway. The results may offer a novel explanation of JTSHF to prevent against diabetes and IR-related metabolic diseases.…”

Whole-brain Functional Networks in Cognitively Normal, Mild Cognitive Impairment, and Alzheimer’s Disease by Eun Hyun Seo (106201)

“…In contrast, individual parameters of the network were altered with the following patterns of changes: local clustering of networks was lower in both MCI and AD compared to CN, while path length was not different among the three groups. Then, MCI had a lower level of local clustering than AD. Subgroup analyses for AD also revealed that very mild AD had lower local clustering and shorter path length compared to mild AD. …”

Results of ablation experiments. by Haisong Xu (141729)

“…First, an efficient channel attention mechanism (ECA) is inserted in the layer before the SPPF in the backbone network, which realizes efficient computation of channel attention and reduces redundant computation while decreasing the model complication. Second, using the Content-Aware ReAssembly of Features (CARAFE) module instead of the original nearest-neighbor up-sampling module achieves light weighting while allowing for better aggregation of contextual information within a larger sensory field, which effectively improves the diversity and effectiveness of the model. …”

Data_Sheet_1_Communication Mechanism and Optimization Strategies of Short Fitness-Based Videos on TikTok During COVID-19 Epidemic Period in China.PDF by Jinlong Shi (495868)

“…Through the communication channels mainly composed of texts, pictures, and audio, the communication subjects carry out multilevel interactive communication with the communication objects; (2) fitness preferences are mainly composed of dances, unarmed fitness, and fitness with equipment; (3) from the perspective of time, taking February 20 as the node, the daily number of released short videos shows a trend of “increase before decrease”; from the perspective of space, the distribution is significantly unbalanced across provinces, and the direction is not apparent; and (4) this article explores the communication mechanism and targeted optimization countermeasures of short fitness-based videos on TikTok in China's COVID-19 epidemic period.…”

Table_2_Antidiabetic effect of sciadonic acid on type 2 diabetic mice through activating the PI3K-AKT signaling pathway and altering intestinal flora.DOCX by Lin Chen (54305)

“…<p>Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by hyperglycemia. …”

<i>Drosophila</i> Mitf regulates the V-ATPase and the lysosomal-autophagic pathway by Valentina Bouché (842830)

“…Furthermore, we show Mitf-mediated clearance of cytosolic and nuclear expanded ATXN1 (ataxin 1) in a cellular model of spinocerebellar ataxia type 1 (SCA1). …”

Table_1_Roles of Gastric Emptying and Gastrointestinal Transit Following Ileal Interposition in Alleviating Diabetes in Goto-Kakizaki Rats.docx by Yanmin Wang (660089)

“…</p>Conclusions<p>Although IT inhibits the GI transit time, the earlier interaction between undigested nutrients and interpositioned ileum promotes gut hormone secretion and thus reduces body weight and alleviates hyperglycemia. A decrease of GI transit of IT rats exacerbates the antidiabetic effects.…”

Data_Sheet_1_Populus SVL Acts in Leaves to Modulate the Timing of Growth Cessation and Bud Set.PDF by Domenique André (12098645)

“…<p>SHORT VEGETATIVE PHASE (SVP) is an important regulator of FLOWERING LOCUS T (FT) in the thermosensory pathway of Arabidopsis. It is a negative regulator of flowering and represses FT transcription. …”

Table_1_The Aging Features of Thyrotoxicosis Mice: Malnutrition, Immunosenescence and Lipotoxicity.xlsx by Qin Feng (147009)

“…The results of routine blood tests and flow cytometry showed that immunosenescence occurred in thyrotoxicosis mice, which was characterized by a significant decrease in neutrophils, lymphocytes, CD4+/CD8+ and CD4+IFN-γ+ lymphocytes. …”

Table_1_Identifying and validating subtypes of Parkinson's disease based on multimodal MRI data via hierarchical clustering analysis.docx by Kaiqiang Cao (9348026)

“…The “mild subtype” was characterized by increased ALFF in the frontal lobe, temporal lobe, and sensorimotor cortex, and a slight decrease in GMV with mild impairment of motor function and cognitive function.…”

Expression of Sox2, Sox10, Gata3, Prox1 and Peripherin during primary auditory neuron development and maturation. by Koji Nishimura (2077804)

“…Downward and upward inflections indicate the corresponding decrease and increase in expression, respectively. …”

Whole worm lipid quantification in LIU1 and LIU2 strains alone or crossed with either tub-1 or tub-2 knockout strains. by Andrew S. Clark (16510496)

“…LIU1 crosses, in which a GFP fusion protein localizes to lipid droplets in the intestine, shows no difference in fluorescence across controls or mutants (One-way ANOVA with Tukey’s post-hoc, n = 90, 93, 93 respectively. …”

Pedogenesis of high-mountain soils from Serra da Mantiqueira, Brazil by Rafael Cipriano da Silva (4617679)

“…The variation in the isotopic signature of δ13C indicates a drier past condition, with mixed vegetation, with gradual change of vegetation with predominant C3 photosynthetic pathway. …”

Data_Sheet_6_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

“…Therefore, our results explain one underlying mechanism of increasing the sensitivity of osteosarcoma to chemotherapy and suggest that Sestrin2 is a promising gene target.</p>…”

Submicroscopic malaria in pregnancy (sMiP) over the 4 years from 2012 to 2015. by Mary Ellen Gilder (8919374)

“…<p>There was a substantial decrease in the weighted proportion of sMiP for all species from the 4th quarter 2012 to the 4th quarter of 2015. …”

DataSheet_2_Methylome changes in Lolium perenne associated with long-term colonisation by the endophytic fungus Epichloë sp. LpTG-3 strain AR37.zip by Flavia Pilar Forte (6831152)

“…Our results showed that the presence of the endophyte leads to a decrease in DNA methylation across genomic features, with differentially methylated regions primarily located in intergenic regions and CHH contexts. …”

Image_4_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.TIF by Zhen Tang (2977569)

“…Therefore, our results explain one underlying mechanism of increasing the sensitivity of osteosarcoma to chemotherapy and suggest that Sestrin2 is a promising gene target.</p>…”