Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells by Alshwyeh, Hussah Abdullah

“…Furthermore, the extract exhibited higher toxicity towards NCI-H292 cells, followed by A549 and normal MRC-5 cells in decreasing order of potency. …”
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Table S2. Summary of proteins indentified in the secretome of WT and ∆pldA strains from The outer membrane phospholipase A is essential for membrane integrity and type III secretio... by Xia Wang (36364)

“…Furthermore, the <i>ΔpldA</i> mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. …”

HtrA1 suppresses the growth of pancreatic cancer cells by modulating Notch-1 expression by Hao Cheng (103394)

“…Consistently, HtrA1 levels were also decreased in two human pancreatic cancer cell lines, PANC-1 and BXPC-3. …”

Table S4. Differential expression analysis of the transcriptome of WT and ΔpldA strains from The outer membrane phospholipase A is essential for membrane integrity and type III sec... by Xia Wang (36364)

“…Furthermore, the <i>ΔpldA</i> mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. …”

Table S5. Secretome of S. flexneri WT and related strains in the presence of Congo Red from The outer membrane phospholipase A is essential for membrane integrity and type III secr... by Xia Wang (36364)

“…Furthermore, the <i>ΔpldA</i> mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. …”

Table S3. OM profile of WT and ΔpldA strains from The outer membrane phospholipase A is essential for membrane integrity and type III secretion in <i>Shigella flexneri</i> by Xia Wang (36364)

“…Furthermore, the <i>ΔpldA</i> mutant strain showed decreased levels of type III secretion system expression, contributing to the reduced internalization efficiency in host cells. …”

A Model of Post-Infection Fatigue Is Associated with Increased TNF and 5-HT_2A Receptor Expression in Mice by Yvonne Couch (766341)

“…At 24 hours post-injection mice exhibit no overt changes in locomotor behaviour, but do show increased immobility in a forced swim test, as well as decreased sucrose preference and reduced marble burying activity, indicating a depressive-like state. …”

Supplementary Material for: CD4+CD25+ Regulatory T Cells Inhibit Natural Killer Cell Hepatocytotoxicity of Hepatitis B Virus Transgenic Mice via Membrane-Bound TGF-β and OX40 by Chen Y. (3114699)

“…In this study, using the NK cell-mediated oversensitive liver injury model of hepatitis B virus transgenic (HBs-Tg) mice triggered by a low dose of concanavalin A, it was observed that an increased number of CD4+CD25+Foxp3+ Tregs were accumulated in the liver, along with the recovery of liver injury. …”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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Image 2_Maternal benzo[a]pyrene exposure during critical gestational periods impairs offspring neurological development in rats: a mechanistic study of the Wnt/β-catenin signaling... by Nan Zhang (46264)

“…Introduction<p>Mid-gestation is a critical period for the development of the nervous system. …”

Image 1_Maternal benzo[a]pyrene exposure during critical gestational periods impairs offspring neurological development in rats: a mechanistic study of the Wnt/β-catenin signaling... by Nan Zhang (46264)

“…Introduction<p>Mid-gestation is a critical period for the development of the nervous system. …”

Inhibition of Wnt/β-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8 by Ismaïl Hendaoui (43729)

“…Here, using low concentrations of soluble FZC18 and Wnt3a, we show that they physically interact in a cell-free system. …”

Image 3_Maternal benzo[a]pyrene exposure during critical gestational periods impairs offspring neurological development in rats: a mechanistic study of the Wnt/β-catenin signaling... by Nan Zhang (46264)

“…Introduction<p>Mid-gestation is a critical period for the development of the nervous system. …”

Image 4_Maternal benzo[a]pyrene exposure during critical gestational periods impairs offspring neurological development in rats: a mechanistic study of the Wnt/β-catenin signaling... by Nan Zhang (46264)

“…Introduction<p>Mid-gestation is a critical period for the development of the nervous system. …”

Peanut (Arachis hypogaea) allergen powder-dnfp (Palforzia™) in peanut allergy: a profile of its use by Young-A Heo (5060039)

“…</p> <p> </p> <p><b>Authorship and conflict of interest</b> Young-A Heo, a salaried employee of Adis International Ltd/Springer Nature and an editor of <em>Drugs & Therapy Perspectives, was not involved in any publishing decisions for the manuscript and declares no </em>declare no relevant conflicts of interest. …”

Annexin A2 Is a Natural Extrahepatic Inhibitor of the PCSK9-Induced LDL Receptor Degradation by Nabil G. Seidah (148050)

“…Western blotting and immunohistochemistry of <em>AnxA2^−/−</em> tissues revealed that the LDLR was decreased by ∼50% in extrahepatic tissues, such as adrenals and colon. …”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx by Ningning Chen (509273)

“…We found that the upregulated hsa-miR-33a-5p repressed IGFBP5 translation by forming a silencing complex with Argonaute protein 2 (AGO2) in a real-ambient PM exposure system, which further led to the suppression of the ERK1/2-SOD2 signaling pathway and increased levels of ROS.…”

Protein Phosphatase 2A Controls Ethylene Biosynthesis by Differentially Regulating the Turnover of ACC Synthase Isoforms by Kyle R. Skottke (223882)

“…Surprisingly, <em>rcn1</em> plants exhibit decreased accumulation of the ACS5 protein, suggesting that a regulatory phosphorylation event leads to ACS5 destabilization. …”

Inhibition of Neuroblastoma Tumor Growth by Targeted Delivery of MicroRNA-34a Using Anti-Disialoganglioside GD₂ Coated Nanoparticles by Amanda Tivnan (163017)

“…These tumors express high levels of the cell surface antigen disialoganglioside GD2 (GD₂), providing a target for tumor-specific delivery.</p> <h3>Principal Findings</h3><p>Nanoparticles encapsulating miR-34a and conjugated to a GD₂ antibody facilitated tumor-specific delivery following systemic administration into tumor bearing mice, resulted in significantly decreased tumor growth, increased apoptosis and a reduction in vascularisation. …”